22 Google Trending Breakout Blog Post Ideas – Updated on 2022-03-02

Find trends and resources for the highest search-volume keywords on Google in the last 24 hours below. This post was updated on 2022-03-02.

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Please note that everything on this page is automatically gathered and generated. Skim through blog post ideas until you find something you’re interested in writing about. Take the hard work out of finding and researching popular blog post ideas.

Post Idea #1: Bank of Canada – Banque du Canada

Related Articles – Summarized

Bank Of Canada

The Bank of Canada is a Crown corporation and Canada’s central bank.

The Bank of Canada headquarters are located at the Bank of Canada Building, 234 Wellington Street in Ottawa, Ontario.

The bank was chartered by and under the Bank of Canada Act on 3 July 1934, as a privately owned corporation, a move taken in order to ensure the bank would be free from partisan political influence.

On 11 March 1935, the Bank of Canada began operations, following the granting of royal assent to the Bank of Canada Act.

The mandate of the Bank of Canada is defined in the Bank of Canada Act preamble and it states,.

The Bank of Canada is the sole entity authorized to issue currency in the form of bank notes in Canada.

The Bank of Canada 2008 balance sheet expanded to $78.3 billion from $53.7 billion from the previous year, as the bank created new money to fund emergency loans to Canada’s major banks by purchasing their assets on a temporary basis.

Post Idea #2: Central bank

Related Articles – Summarized

Central Bank Definition

In modern economies, the central bank is usually responsible for the formulation of monetary policy and the regulation of member banks.

Finally, a central bank also acts as an emergency lender to distressed commercial banks and other institutions, and sometimes even a government.

QE essentially involves a central bank creating new money and using it to buy securities from the nation’s banks so as to pump liquidity into the economy and drive down long-term interest rates.

While the ECB was the first major central bank to experiment with negative interest rates, a number of central banks in Europe, including those of Sweden, Denmark, and Switzerland, have pushed their benchmark interest rates below the zero bound.

Central bank balance sheets are bloating: Large-scale asset purchases by the Federal Reserve, Bank of Japan, and the ECB are swelling balance sheets to record levels.

Shrinking these central bank balance sheets may have negative consequences down the road. In Japan and Europe, the central bank purchases included more than various non-government debt securities.

Currently, the Federal Reserve, the European Central Bank, and other major central banks are under pressure to reduce the balance sheets that ballooned during their recessionary buying spree.

Our Central Focus Is You

Whether that’s enjoying your family, going out with friends, or just reading a good book.

Central Bank’s online account opening makes that all possible with our quick, easy and secure process.

Central Bank

There is very strong consensus among economists that an independent central bank can run a more credible monetary policy, making market expectations more responsive to signals from the central bank.

Even the People’s Bank of China has been accorded great latitude, though in China the official role of the bank remains that of a national bank rather than a central bank, underlined by the official refusal toUnpegthe yuan or to revalue itUnder pressure“.

Evolving further partly in response to the European Central Bank, the People’s Bank of China had by 2000 become a modern central bank.

The role of a central bank was ended in the Bank War of the 1830s by President Andrew Jackson when he shut down the Second Bank as being too powerful and elitist.

There is no standard terminology for the name of a central bank, but many countries use theBank of [Country]” form-for example: Bank of Canada, Bank of Mexico, Bank of Thailand.

Some are styledNationalbanks, such as the Swiss National Bank, National Bank of Poland and National Bank of Ukraine, although the term national bank is also used for private commercial banks in some countries such as National Bank of Pakistan.

Some state-owned commercial banks have names suggestive of central banks, even if they are not: examples are the State Bank of India and Central Bank of India.

Post Idea #3: Fixed-rate mortgage

Related Articles – Summarized

Fixed-Rate Mortgage Definition

The termFixed-rate mortgagerefers to a home loan that has a fixed interest rate for the entire term of the loan.

So the interest rate in a fixed-rate mortgage stays the same regardless of where interest rates go-up or down.

Most mortgagors who purchase a home for the long term end up locking in an interest rate with a fixed-rate mortgage.

While the interest rate on the mortgage and the amounts of the monthly payments themselves don’t change, the way that your money is applied does.

Most amortized loans come with fixed interest rates, although there are cases where non-amortizing loans have fixed rates, too.

That’s because the interest rate in a fixed-rate mortgage doesn’t change for every installment payment.

These loans typically charge monthly interest based on a fixed rate.

Fixed-Rate Mortgage Loans And Rates At Bank Of America

A fixed-rate mortgage offers you consistency that can help make it easier for you to set a budget.

Your mortgage interest rate, and your total monthly payment of principal and interest, will stay the same for the entire term of the loan.

Think interest rates could rise in the next few years and you want to keep the current rate.

Prefer the stability of a fixed principal and interest payment that doesn’t change.

Today’s low ratesfor fixed-rate mortgagesOther types of mortgages.

Fixed-Rate Mortgages: A Guide

A fixed-rate mortgage has an interest rate that remains the same for the life of the loan.

Fixed-rate mortgages are the most popular type of financing because they offer predictability and stability you’ll never be surprised by the principal and interest charges in your monthly mortgage payment, because they’ll stay the same for the entire loan term.

FHA, VA, USDA FHA loans, VA loans and USDA loans have fixed rates and come with less strict requirements than conventional loans.

Amortizing The vast majority of fixed-rate mortgages are amortizing loans, which means that your monthly payments go toward both the principal and the interest charges.

For virtually the same monthly payment, Jill can borrow $88,000 more with a 30-year fixed loan.

Fixed-rate mortgages vs. adjustable-rate mortgages.

True to its name, the rate on an ARM adjusts as the market changes, but the loan comes with an introductory rate for a period of time.

Fixed-Rate Mortgage: What It Is And When To Use One – Forbes Advisor

A fixed-rate mortgage is a type of loan that is secured by real estate and has an interest rate that remains unchanged during the mortgage term.

These mortgages are ideal for borrowers who want to lock in their interest rate and always know what their monthly payment will be and how much interest they’ll pay over the life of their loan.

Fixed-rate mortgages are one of the most common types of real estate loans, along with adjustable-rate mortgages, which may see interest rate changes over time.

Fixed-rate loans charge the same interest rate throughout the loan term.

If a fixed-rate mortgage isn’t an option-or if you can qualify for a loan with a higher rate-then you may want to consider another type of mortgage.

These loans are never set-they fluctuate from month to month based on an underlying rate like the London Interbank Offered Rate or prime rate.

Fixed rates are often higher than introductory rates for ARMs. Loans are secured by your property, so you can lose the property if you default on payments.

Fixed-Rate Mortgage: What You Need To Know

A fixed-rate mortgage is a home loan with an interest rate that stays the same.

It’s the most common term for a fixed-rate purchase mortgage.

15-year: Most mortgage lenders offer a 15-year term.

Compared to a 30-year mortgage of the same amount, a 15-year loan has higher monthly payments, but lower interest charges over the life of the loan.

For a given loan amount, the monthly payments are more affordable than on a 15-year mortgage and less affordable than on a 30-year mortgage.

If mortgage rates rise after you get your home loan, you have the safeguard of an unchanging rate on your fixed-rate mortgage.

If interest rates fall after you get your home loan, the only way to take advantage of lower mortgage rates is to refinance.

March 2, 2022: Rates Down For Fixed-Rate Loans

On March 2, 2022, average mortgage rates were down for fixed rate options.

Check out today’s average rates below to see how they’re trending on fixed and adjustable rate loans as the month of March gets underway.

The average 20-year mortgage rate today is 3.794%, down 0.057% from yesterday’s average of 3.851%. You’d be looking at a principal and interest payment of $595 per $100,000 borrowed at today’s average rate.

The average 15-year mortgage rate today is 3.385%, down 0.027% from yesterday’s average of 3.412%. A mortgage loan at today’s average interest rate would cost you $709 per $100,000 borrowed.

You save a lot of money with this option over time, but your monthly payments are much higher so they can affect your budget flexibility during the years you’re working on paying down the loan.5/1 ARMs. The average 5/1 ARM rate is 3.432%, up 0.064% from yesterday’s average of 3.368%. This rate is guaranteed for the first five years, but can change once per year after that.

A mortgage rate lock guarantees you a certain interest rate for a specified period of time usually 30 days, but you may be able to secure your rate for up to 60 days.

A floating rate lock lets you secure a lower rate on your mortgage if rates fall prior to your closing, and while today’s rates are still quite low, we don’t know if rates will go up or down over the next few months.

Fixed-Rate Mortgage

A fixed-rate mortgage is a mortgage loan where the interest rate on the note remains the same through the term of the loan, as opposed to loans where the interest rate may adjust orFloat“.

In the United States, United States Federal Housing Administration helped develop and standardize the fixed rate mortgage as an alternative to the balloon payment mortgage by insuring them and by doing so helped the mortgage design garner usage.

The fixed-rate mortgage was the first mortgage loan that was fully amortized precluding successive loans, and had fixed interest rates and payments.

In Canada, the longest term for which a mortgage rate can be fixed is typically no more than ten years, while mortgage maturities are commonly 25 years.

A fixed rate mortgage in Singapore has the interest rate fixed for only the first three to five years of the loan, and it then becomes variable.

In Australia, “Honeymoonmortgages with introductory rates are common, but can last as short as a year, and may instead offer a fixed reduction in interest rate rather than a fixed rate itself.

The fixed monthly payment for a fixed rate mortgage is the amount paid by the borrower every month that ensures that the loan is paid off in full with interest at the end of its term.

Post Idea #4: Refinancing

Related Articles – Summarized

How Does Refinancing Work? How And When To Refi

Refinancing is when you replace an existing loan with a new loan.

Refinancing works by acquiring a new mortgage loan which is used to pay off and close the original loan.

If you refinance to a 30-year mortgage, it doesn’t matter how many years you paid on your original loan your payment cycle with the new loan will start over and continue for 30 years.

A good time to refinance is when you can qualify for a low enough interest rate to save money over the life of your loan, even after the cost of refinancing.

Home condition: Lenders may require an appraisal to assess your home’s value, which helps them determine how much money they’re willing to loan you.

Depending on how far along you are in your mortgage loan term, you may need a lower refinance interest rate to see the financial savings you were expecting.

If you request it, each lender can provide you with a Loan Estimate, which includes the terms of the loan, projected payments if you were to take out the loan and a summary of loan costs and fees.

Refinancing: What Is It?

Refinancing involves replacing an existing loan with a new loan that pays off the debt of the first one.

The finer details of a refinancing can vary depending on the type of loan and your lender.

Your collateral is always at risk unless you refinance a loan into a personal unsecured loan, which doesn’t use property as collateral.

You might want to refinance a 30-year home loan into a 15-year home loan that comes with higher monthly payments but a lower interest rate.

Federal student loans are more flexible than private student loans if you fall on hard times, offering deferment or forbearance plans that grant you a temporary reprieve from making payments.

Refinancing is like shopping for any other loan or mortgage.

It’s worthwhile to consider refinancing a loan in a few instances.

Refinance Definition

Common goals from refinancing are to lower one’s fixed interest rate to reduce payments over the life of the loan, to change the duration of the loan, or to switch from a fixed-rate mortgage to an adjustable-rate mortgage or vice versa.

Consumer loans typically considered for refinancing include mortgage loans, car loans, and student loans.

Rate-and-term refinancing occurs when the original loan is paid and replaced with a new loan agreement that requires lower interest payments.

Cash-in refinancing: A cash-in refinance allows the borrower to pay down some portion of the loan for a lower loan-to-value ratio or smaller loan payments.

Consolidation refinancing: In some cases, a consolidation loan may be an effective way to refinance.

If your loan term is reset to its original length, your total interest payment over the life of the loan may outweigh what you save at the lower rate.

Your monthly payment increases with a shorter loan term, and you have to pay closing costs on the refinance.

Current Refinance Rates

Some lenders provide their mortgage loan terms to Bankrate for advertising purposes and Bankrate receives compensation from those advertisers.

In the above table, an Advertiser listing can be identified and distinguished from other listings because it includes aNextbutton that can be used to click-through to the Advertiser’s own website or a phone number for the Advertiser.

Availability of Advertised Terms: Each Advertiser is responsible for the accuracy and availability of its own advertised terms.

Bankrate cannot guaranty the accuracy or availability of any loan term shown above.

Loan Terms for Bankrate.com Customers: Advertisers may have different loan terms on their own website from those advertised through Bankrate.com.

Loans Above $548,250 May Have Different Loan Terms: If you are seeking a loan for more than $548,250, lenders in certain locations may be able to provide terms that are different from those shown in the table above.

Consumer Satisfaction: If you have used Bankrate.com and have not received the advertised loan terms or otherwise been dissatisfied with your experience with any Advertiser, we want to hear from you.

Refinancing A Mortgage: How It Works

If you choose a different lender, that new lender pays off your current loan, ending your relationship with your old lender.

The rate lock period depends on a few factors like your location, loan type and lender.

During underwriting, your mortgage lender verifies your financial information and makes sure that everything you’ve submitted is accurate.

If you’re trying to lower your mortgage payment, then the value could impact whether you have enough home equity to get rid of private mortgage insurance or be eligible for a certain loan option.

A few days before closing, your lender will send you a document called a Closing Disclosure.

The closing is attended by the people on the loan and title and a representative from the lender or title company.

If your lender owes you money, you’ll receive the funds after closing.

Refinancing| How Does Refinancing Loans Work?

A borrower must evaluate his needs and then accordingly choose the type of refinancing loan.

3 Consolidation Refinancing This type of refinancing option is considered best for some cases and it can be taken into use when investors take-up a loan that is way lesser than their ongoing average rate of interest across all other credit goods and services.

Consolidation refinancing requires the individuals or companies to take up a loan at a low rate and then get rid of the ongoing debt with the same.

Car loans, student loans, mortgage loans, etc are types of customer loans that are mostly preferred for refinancing.

Commercial properties might always be chosen for refinancing by commercial investors and most of them would prefer to evaluate their company’s balance sheets for borrowing loans that are issued by the creditors for the purpose of deriving benefits as a result of improved credit profile or lower market rates.

Availing Fixed-Rate Loans Having an adjustable-rate loan can help the borrower save money in the short term but can be potentially dangerous if the payment rises all of a sudden as a result of the rate change.

Conclusion Refinancing occurs when a current loan undergoes modification with respect to the payment schedule, interest rate, etc.

Auto Loan Refinancing

Things may have changed since you bought your car, which means you might be in a better position to lower your car payment or your annual percentage rate-or both.

That could translate to immediate savings every month or long term over the life of your auto loan.

Pre-qualify to see real numbers without hurting your credit score.

Just ask the thousands of others we’ve helped refinance.

Pre-qualify with no impact to your credit score to see if an auto refinance could help your budget go further.

Post Idea #5: Respiratory syncytial virus

Related Articles – Summarized


Respiratory syncytial virus, or RSV, is a common respiratory virus that usually causes mild, cold-like symptoms.

Most people recover in a week or two, but RSV can be serious, especially for infants and older adults.

RSV is the most common cause of bronchiolitis and pneumonia in children younger than 1 year of age in the United States.

NIH: National Institute Of Allergy And Infectious Diseases

Respiratory syncytial virus, or RSV, is a respiratory virus that infects the lungs and breathing passages.

RSV can be serious, particularly for infants and the elderly.

RSV is the most common cause of bronchiolitis and pneumonia in children younger than 1 year of age in the United States.

In the United States, nearly all children become infected with RSV by age 2, with 75,000 to 125,000 of them hospitalized each year.

Globally, RSV affects an estimated 64 million people and causes 160,000 deaths each year.

NIAID conducts and supports basic research on RSV to improve our understanding of the virus and how it causes disease, as well as factors in animals and humans that affect susceptibility to RSV infection.

Scientists in NIAID labs and in universities and medical research centers across the United States work together to translate this knowledge into new, safe, and effective ways to treat and prevent RSV. Latest News Releases.

Respiratory Syncytial Virus

Respiratory syncytial virus causes infections of the lungs and respiratory tract.

RSV can cause severe infection in some people, including babies 12 months and younger, especially premature infants, older adults, people with heart and lung disease, or anyone with a weak immune system.

Signs and symptoms of respiratory syncytial virus infection most commonly appear about four to six days after exposure to the virus.

RSV infection can spread to the lower respiratory tract, causing pneumonia or bronchiolitis inflammation of the small airway passages entering the lungs.

Because RSV and coronavirus disease 2019 are both types of respiratory viruses, some symptoms of RSV and COVID-19 can be similar.

By age 2, most children will have been infected with respiratory syncytial virus, but they can get infected by RSV more than once.

There may be a link between severe RSV in children and the chance of developing asthma later in life.

Respiratory Syncytial Virus Infections

Respiratory syncytial virus, or RSV, is a common respiratory virus.

Who is at risk for respiratory syncytial virus infections?

What are the symptoms of respiratory syncytial virus infections?

How are respiratory syncytial virus infections diagnosed?

What are the treatments for respiratory syncytial virus infections?

Can respiratory syncytial virus infections be prevented?

Article: The 2018 annual cost burden for children under five years of…. Article: Early innate immune response triggered by the human respiratory syncytial virus…. Article: A comparative analysis of the epidemiology of influenza and respiratory syncytial…. Respiratory Syncytial Virus Infections see more articles.

Respiratory Syncytial Virus

RSV infection can present with a wide variety of signs and symptoms that range from mild upper respiratory tract infections to severe and potentially life-threatening lower respiratory tract infections requiring hospitalization and mechanical ventilation.

While RSV can cause respiratory tract infections in people of all ages and is among the most common childhood infections, its presentation often varies between age groups and immune status.

Most childhood RSV infections are fairly self-limited with typical upper respiratory tract signs and symptoms, such as nasal congestion, runny nose, cough, and low-grade fever.

Population Risk factors for progression to lower respiratory infection with RSV Children Prematurity.

This is synonymous with Human respiratory syncytial virus and is often shortened to just RSV. It belongs to the genus Orthopneumovirus, family Pneumoviridae, order Mononegavirales.

In the United States, RSV is responsible for up to 20% of acute respiratory infection hospitalizations in children under the age of 5.

RSV was first discovered in 1956 when researchers isolated a virus from a population of chimpanzees with respiratory illness.

Respiratory Syncytial Virus: From Pathogenesis To Potential Therapeutic Strategies

Wertz GW, Collins PL, Huang Y, Gruber C, Levine S, Ball LA. Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein.

Bukreyev A, Yang L, Fricke J, Cheng L, Ward JM, Murphy BR, Collins PL. The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes.

Lingemann M, McCarty T, Liu X, Buchholz UJ, Surman S, Martin SE, Collins PL, Munir S. The alpha-1 subunit of the Na+,K+-ATPase is required for macropinocytic entry of respiratory syncytial virus in human respiratory epithelial cells.

Brown G, Rixon HW, Steel J, McDonald TP, Pitt AR, Graham S, Sugrue RJ. Evidence for an association between heat shock protein 70 and the respiratory syncytial virus polymerase complex within lipid-raft membranes during virus infection.

Bermingham A, Collins PL. The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcription.

Van Erp EA, Lakerveld AJ, de Graaf E, Larsen MD, Schepp RM, Hipgrave Ederveen AL, Ahout IM, de Haan CA, Wuhrer M, Luytjes W, Ferwerda G, Vidarsson G, van Kasteren PB. Natural killer cell activation by respiratory syncytial virus-specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc-glycosylation.

Cunningham S, Piedra PA, Martinon-Torres F, Szymanski H, Brackeva B, Dombrecht E, Detalle L, Fleurinck C. Nebulised ALX-0171 for respiratory syncytial virus lower respiratory tract infection in hospitalised children: a double-blind, randomised, placebo-controlled, phase 2b trial.

Respiratory Syncytial Virus Infection In Adults

Human respiratory syncytial virus belongs to the recently defined Pneumoviridae family, Orthopneumovirus genus.

It is a negative sense, single stranded RNA virus that results in epidemics of respiratory infections that typically peak in the winter in temperate climates and during the rainy season in tropical climates.

Generally, one of the two genotypes predominates in a single season, alternating annually, although regional variation occurs.

RSV is a cause of disease and death in children, older people, and immunocompromised patients, and its clinical effect on adults admitted to hospital is clarified with expanded use of multiplex molecular assays.

Among adults, RSV produces a wide range of clinical symptoms including upper respiratory tract infections, severe lower respiratory tract infections, and exacerbations of underlying disease.

Here we discuss the latest evidence on the burden of RSV related disease in adults, especially in those with immunocompromise or other comorbidities.

We review current therapeutic and prevention options, as well as those in development.

Post Idea #6: Breakthrough therapy

Related Articles – Summarized

A Breakthrough In Therapy. Now What’S That Really Mean?

If you are in therapy, or have read about what happens in therapy, you have probably heard the wordBreakthrough.” Clients in therapy use it a lot, and so do therapists.

Generally, we think of a breakthrough a point in therapy when a client makes an important realization.

Opening up to your therapist about feelings can be a breakthrough in your therapy.

Of course, you may have another question about breakthroughs in therapy.

Keep in mind that a breakthrough in therapy may occur after what feels like a long time, weeks, months, of essentiallyTreading waterwhile you and your therapist work together to discuss and understand an issue that may be especially painful or complicated.

You may not even be aware that a breakthrough occurred until you find yourself thinking or behaving in a way that leads to more quality in your life and in your relationships.

So how’s your therapy going? Progress in therapy isn’t only measured in breakthroughs.

What Exactly Is A ‘Breakthrough’ In Therapy?

Understanding what a breakthrough looks like to you can help you notice if you’re progressing and the work, time and money you’re putting into therapy is actually paying off.

Though breakthroughs are often thought of as these huge, cinematic moments, both Rodriguez and Morton agree that they can be much more subtle like adopting a new, healthy coping skill, or making a small step toward a goal you’ve been trying to achieve in therapy for months.

Breakthroughs in therapy are, in the simplest of terms, small or large enlightening moments that mean you’re making progress.

Despite the misconception that a breakthrough in therapy is a destination, it is less like a finish line and more akin to the first day of training for a triathlon.

I have had several breakthrough moments in therapy From that moment comes a surge of courage to work through it,” said Achea Redd., a mental health advocate, author and the founder of Real Girls F.A.R.T. While it’s normal to plateau in therapy from time to time, there are things that can block you from having a breakthrough and from generally progressing in therapy.

All the tiny victories you have in therapy, the little heartaches, or seemingly small goals you reach can be breakthrough moments whether or not you realize it at the time.

In truth, there’s no recipe to having aBreakthroughin therapy.

Breakthrough Speech & Occupational Therapy Center – Davie, FL

Wii Habilitation The popular gaming system, Sony’s Wii, is the heart of Breakthrough Therapy ServicesWii Habilitation“, a fun-filled, alternative therapeutic tool and curriculum utilized by our Speech-Language Pathologists…. more on Alternative Therapy Autism.

If your child has been diagnosed with autism or you suspect other developmental problems alongThe spectrumorAutism spectrum disorders“, you might be frightened and stressed.

Or, you may be concerned by the social,…. more on Autism Occupational Therapy.

Occupational Therapists at Breakthrough Therapy services work collaboratively with your child and family to enhance your child’s ability to participate in daily activities…. more on Occupational Therapy Speech Therapy.

Speech Language Pathology is separated into three essential fields: 1) Voice, 2) Speech, & 3) Language Each field contains its own set of disorders and disabilities, which through committed and goal-specifi…. more on Speech Therapy.

FDA Grants BI 1015550 Breakthrough Therapy Designation For Idiopathic Pulmonary Fibrosis

PRNewswire/ Boehringer Ingelheim announced today that the U.S. Food and Drug Administration granted Breakthrough Therapy Designation to its novel investigational therapy, BI 1015550, for the treatment of idiopathic pulmonary fibrosis.

BI 1015550 is an oral, phosphodiesterase 4B inhibitor with the potential to address both pulmonary fibrosis an irreversible scarring of lung tissue that negatively impacts lung function and inflammation associated with progressive fibrosing interstitial lung diseases.

The accelerated development of BI 1015550 is part of Boehringer Ingelheim’s next wave of potential innovative treatments for interstitial lung diseases aimed at preserving lung function and improving the lives of patients,” said Thomas Seck, M.D., senior vice president, Medicine and Regulatory Affairs, Boehringer Ingelheim Pharmaceuticals, Inc.BI 1015550 represents the first molecule in the class of PDE4B inhibitors that is being studied for IPF and other progressive fibrosing ILDs. We have built on our heritage in pulmonary fibrosis and are acting on the breakthrough designation and clinical data with the goal that this potential novel medicine can reach patients as soon as possible.”

BI 1015550 was studied as a monotherapy or in combination with background antifibrotic therapy to assess the effectiveness of slowing the rate of lung function decline in patients with IPF. The efficacy, safety, and tolerability of BI 1015550 was studied in a Phase II randomized, double-blind, placebo-controlled trial of patients with IPF. The primary endpoint was change from baseline in Forced Vital Capacity a measure of lung function over a 12-week treatment period.

The FDA Breakthrough Therapy designation is supported by data collected to date.

The FDA established the Breakthrough Therapy Designation process to expedite the development and review of drugs for serious or life-threatening conditions where preliminary clinical evidence indicate that the therapy may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints.

ILDs encompass more than 200 disorders that can lead to pulmonary fibrosis an irreversible scarring of lung tissue that negatively impacts lung function and may become life-threatening.

Breakthrough Therapy

Breakthrough therapy is a United States Food and Drug Administration designation that expedites drug development that was created by Congress under Section 902 of the 9 July 2012 Food and Drug Administration Safety and Innovation Act.

The FDA’sBreakthrough therapydesignation is not intended to imply that a drug is actually aBreakthroughor that there is high-quality evidence of treatment efficacy for a particular condition; rather, it allows the FDA to grant priority review to drug candidates if preliminary clinical trials indicate that the therapy may offer substantial treatment advantages over existing options for patients with serious or life-threatening diseases.

The FDA has other mechanisms for expediting the review and approval process for promising drugs, including fast track designation, accelerated approval, and priority review.

A breakthrough therapy designation can be assigned to a drug if”it is a drug which is intended alone or in combination with one or more other drugs to treat a serious or life threatening disease or conditionand if the preliminary clinical evidence indicates that the drug may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints, such as substantial treatment effects observed early in clinical development.

Sponsors must apply for breakthrough status separately for each indication they intend to label the drug for.

The FDA works with the sponsor of the drug application to expedite the approval process.

Critics have said that the name is misleading and provides companies that obtain a breakthrough designation for a drug candidate with a marketing advantage that may be undeserved.

Post Idea #7: Goldman Sachs

Related Articles – Summarized

Goldman Sachs

In October 2016, Goldman Sachs Bank USA started offering no-fee unsecured personal loans under the brand Marcus by Goldman Sachs.

For charges brought for the same case in other countries, Goldman Sachs agreed in October of the same year to pay more than $2.9 billion, with over $2 billion going to fines imposed in the US. In August 2021, Goldman Sachs announced that it had agreed to acquire NN Investment Partners, which had US$335 billion in assets under management, for1.7 billion from NN Group.

Jim and Janet Baker, founders and together 50% owners of Dragon, filed a lawsuit against Goldman Sachs, alleging negligence, intentional and negligent misrepresentation, and breach of fiduciary duty since Goldman did not warn Dragon or the Bakers of the accounting problems of the acquirer, L&H. On January 23, 2013, a federal jury rejected the Bakersclaims and found Goldman Sachs not liable to the Bakers.

Goldman Sachs was charged for repeatedly issuing research reports with extremely inflated financial projections for Exodus Communications and Goldman Sachs was accused of giving Exodus its highest stock rating even though Goldman knew Exodus did not deserve such a rating.

Unlike many of the Abacus securities, 2007-AC1 did not have Goldman Sachs as a short seller Goldman Sachs lost money on the deal.

Critics of Goldman Sachs point out that Paulson went to Goldman Sachs after being turned down for ethical reasons by another investment bank, Bear Stearns who he had asked to build a CDO. Ira Wagner, the head of Bear Stearns’s CDO Group in 2007, told the Financial Crisis Inquiry Commission that having the short investors select the referenced collateral as a serious conflict of interest and the structure of the deal Paulson was proposing encouraged Paulson to pick the worst assets.

Former Goldman Sachs trader Matthew Marshall Taylor was convicted of hiding $8.3 billion worth of unauthorized trades involving derivatives on the S&P 500 index by makingMultiple false entriesinto a Goldman trading system, with the objective of protecting his year-end bonus of $1.5 million.

Goldman Sachs Group Inc. Sells 331,420 Shares Of Glatfelter Co.

Goldman Sachs Group Inc. lowered its stake in Glatfelter Co. by 83.4% during the 3rd quarter, according to the company in its most recent disclosure with the Securities & Exchange Commission.

Goldman Sachs Group Inc.’s holdings in Glatfelter were worth $931,000 at the end of the most recent reporting period.

Geode Capital Management LLC now owns 727,336 shares of the basic materials company’s stock valued at $10,160,000 after acquiring an additional 23,351 shares in the last quarter.

Metropolitan Life Insurance Co NY now owns 8,245 shares of the basic materials company’s stock valued at $115,000 after acquiring an additional 8,233 shares in the last quarter.

Invesco Ltd. now owns 268,036 shares of the basic materials company’s stock valued at $3,743,000 after acquiring an additional 33,905 shares in the last quarter.

Occudo Quantitative Strategies LP now owns 30,244 shares of the basic materials company’s stock valued at $423,000 after acquiring an additional 17,208 shares in the last quarter.

TheStreet cut shares of Glatfelter from abrating to ac+” rating in a report on Thursday, February 10th. StockNews.com cut shares of Glatfelter from aHoldrating to aSellrating in a report on Monday, February 14th. Shares of GLT stock opened at $12.96 on Wednesday.

Goldman Sachs Advances Further Into Embedded Finance With GM Partnership

Goldman Sachs is moving forward with its embedded finance strategy.

Goldman took over issuing the General MotorsMy GM Rewards card from Capital One; it converted the 3 million GM Rewards cardholders to its consumer business, Marcus, in late February.

There are some people that don’t want to go to their bank,” said Stephanie Cohen, global co-head of consumer and wealth management at Goldman Sachs.

The bank has been pursuing embedded finance since 2019, when Goldman and Apple launched the virtual Apple Card, which was designed for the iPhone and lives in the iPhone wallet.

GreenSky customers will become customers of Goldman Sachs Marcus.

We won’t have to acquire customers one at a time; they will be in Goldman Sachs Marcus,” Cohen said.

We can offer them the broader suite of Goldman Sachs Marcus products and help them better manage their financial life. And it’s a really attractive customer given they own a home and they’re investing in their home.”

Marcus By Goldman Sachs®

Rates of the selected banks reflect New York savings rates for similar products at the select banks with a minimum balance of $2,500.

Rates may vary by state and do not account for bonus, special or promotional APYs.

National Average is based on the APY average for high yield savings accounts with a minimum balance of at least $2,500 offered by the top 50 US banks.

Rates of selected banks and the National Average as reported by Informa Financial Intelligence, www.

Informa has obtained the data from the various financial institutions that it tracks and its accuracy cannot be guaranteed.

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