Consumer Financial Protection Bureau

An official website of the United States government.

We’re the Consumer Financial Protection Bureau, a U.S. government agency that makes sure banks, lenders, and other financial companies treat you fairly.

The content on this page provides general consumer information.

This information may include links or references to third-party resources or content.

We do not endorse the third-party or guarantee the accuracy of this third-party information.

There may be other resources that also serve your needs.

Debt Collection FAQs

The FTC enforces the Fair Debt Collection Practices Act, which makes it illegal for debt collectors to use abusive, unfair, or deceptive practices when they collect debts.

If you don’t recognize a debt, send the debt collector a letter, and ask for verification of the debt.

Once you get the validation information, if you don’t recognize a debt, or don’t think the debt is yours, send the debt collector a dispute letter saying you don’t owe some or all of the money, and ask for verification of the debt.

If a debt collector is trying to collect more than one debt from you, the collector must apply any payment you make to the debt you choose.

If you have an unpaid debt, a creditor or the debt collector it hires may get a court order to try to take money from your bank account to pay the debt.

Debt doesn’t usually go away, but debt collectors do have a limited amount of time to sue you to collect on a debt.

Before you make any payment to settle a debt, get a signed letter from the collector that says the amount you’re paying settles the entire debt – and you no longer owe anything for that debt.

What Is Debt Collection And How Does It Work?

Debt collection is the process of recovering old debt that the borrower has failed to repay.

Debt collection agencies will buy out the original debt for pennies on the dollar after you fail to pay back the debt to the original creditor – and then go after you.

If you don’t dispute the debt within 30 days, the agency considers your debt valid, and they can continue to contact you to collect a debt.

Because of the Fair Debt Collection Practices Act, or FDCPA, you as a consumer don’t have to stand for harassment and threats from debt collectors.

Debt collection agencies are required by the FDCPA to send you a debt validation letter before you pay anything.

A debt validation letter will also outline how much is owed, the type of debt owed, details about the creditor and other important information.

Collecting a past-due debt is a legal way for creditors and debt collection agencies to get money that’s owed to them.

The 5 Best Debt Collection Agencies Of 2022

Rocket Receivables, owned by Transworld Systems, Inc., is a debt collection agency specifically designed for small business owners.

It caters to the healthcare, education, residential, trade, and retail industries, offering simplified debt collection services.

Stage One For accounts that are not yet 120 days past due, stage one is an early intervention debt collection service.

Rocket Receivables guarantees that you’ll get double the money you invested in its stage one, fixed-fee collections program.

Stage Two For older accounts or more complicated cases, stage two includes more intensive debt collection practices, including skip tracing, calls and negotiation tactics, and legal action.

You can’t opt for that debt to be in the cheaper stage one.

For fixed-fee collections in stage one, Rocket Receivables also offers a guarantee: You’ll double the money you pay for the service or you’ll get your money back, minimizing your risk.

Debt Collection

The Debt Collection Center has provided debt collection services to customer agencies since it was established in 1995.

In May 2002, the United States Department of the Treasury designated the Program Support Center as a debt collection center.

This Treasury authority is certified through January 29, 2023.

Repayment Agreements and monthly billing statements.

Referrals of debts to: U.S. Department of Justice for enforced collection.

HHS’ Office of Inspector General for Medicare and Medicaid participation exclusion.

How To Pay Off Debt Collections

Your debt in collections can still be reported to the credit bureaus, and the debt collector still can file a lawsuit against you to recoup its money.

A federal law known as the Fair Debt Collections Practices Act governs how debt collectors interact with you.

Under the Fair Debt Collections Practices Act, a debt collector can’t be abusive, deceptive or unfair when it’s trying to collect money from you.

As we’ve gone over, the best ways to pay off debt that’s gone to collections are to negotiate a lump-sum payment or set up a payment plan.

Starting the process of paying off the debt is a big step toward saying goodbye to debt collectors and, eventually, to the debt.

Prioritizing the debt that’s in collections can help avoid further harm to your credit and can get rid of your debt collection headache.

Collection accounts can drag down your credit scores, but paying off or settling a debt that’s in collections may not necessarily improve your credit scores.

CFPB Examination Procedures Examination Procedures Debt Collection Debt Collection Exam Date: Exam ID No. Prepared By: Reviewer: Docket #: Entity Name: Event #: These examination procedures apply to larger participants in the consumer debt collection market defined by 12 CFR 1090.105 and other entities within the supervisory authority of the Consumer Financial Protection Bureau to the extent that they seek to collect debt from consumers.

b. If the entity falls within the general definition per step 1a above, determine whether the entity nevertheless falls into an exception from the definition of “Debt collector” to the extent that it is: i. Collecting the following types of debts if they are owed to another: A. Debts it originated(F)(ii ; B. Debts that were not in default when they were obtained(F)(iii ; C. Debts that were obtained as security for a commercial credit transaction(F)(iv ; D. Debts if the activity is incidental to a bona fide fiduciary relationship or escrow arrangement(F)(i ; ii.

A debt collector knows or should know that a time or place is inconvenient for a consumer if the consumer uses the word “Inconvenient” or if the facts and circumstances indicate that a time or place is inconvenient for the consumer even if the consumer does not specifically state to the debt collector that a time or place is “Inconvenient”(1)-1). Absent information to the contrary, debt collectors are to assume that calls between 9:00 p.m. and 8:00 a.m. in the consumer’s local time are inconvenient.

Threatening to furnish information to a consumer reporting agency that the debt collector does not actually intend to furnish(1)(v)]; e. Falsely representing or implying that the consumer has committed a crime or other conduct to disgrace the consumer(1)(iv)]; f. Threatening to communicate or communicating to any person credit information which is known or which should be known to be false, including not communicating disputed debts as such(2)]; g. Falsely representing or implying that accounts have been turned over to innocent purchasers for value(1)(vi)]; or h. Using any other false representation or deceptive means to collect or attempt to collect any debt or obtain information concerning a consumer].

Assess whether the debt collector has adequate policies and procedures to avoid disclosure of the existence of a debt to third parties, for example, how does the debt collector identify itself or leave messages with third parties? 17.

For furnishers who are FDCPA debt collectors, determine whether the furnisher engages in “Passive collections” by furnishing information about a debt to a consumer reporting agency before the collector: a. Speaks to the consumer about the debt in person or by telephone; or b. Sends a letter or electronic message to the consumer about the debt and waits a reasonable period of time to receive a notice of undeliverability.

If the debt collector accepts or solicits any postdated payment instruments, assess the following: a. If the debt collector accepts a check or other payment instrument that is postdated by more than five days, determine whether the debt collector provides written notice to the CFPB March 2022 Procedures 33 CFPB Examination Procedures Debt Collection consumer of its intention to deposit the check or instrument three to ten business days prior to depositing the check.

CASE STUDY: QUADRATURE BOOSTER Wilson Transformer Company has manufactured and delivered a Quadrature Booster to UK Power Networks for their Flexible Plug and Play project.

KEY FEATURES > Control the Flow of Real Power on 3-phase Networks > Ideal for Increasing Renewable Generation > Solution to Network Load Sharing Constraints > Custom Design, Test and Manufacture Capability BUILT SMART FOR LIFE Quadrature Booster, also known as phaseshifting transformer, is used to control the flow of real power on three-phase electricity networks.

The Wilson Transformer Company Quadrature Booster is a smart way of managing load sharing constraints in the transmission and distribution networks.

BASIC PRINCIPAL Quad booster technology is based on the principle that active BASIC PRINCIPLE power flow through a transmission line is directly proportional to the Booster sine of the phase angle between the source Quad technology is based on the principle thatterminal active power flowandload through transmission line is directly voltage terminala voltage.

P=|VS |.|VL| sinδ/XL P=|VS |·|VL| sin δ/X L a Quadrature By manipulating the voltage phase angle using Booster, the active power flow can be controlled to within By manipulating the voltage phase angle using aremain Quadrature the constrained rating of theflow “Weaker” The Quadrature Booster, the active power can becircuit.

Theis Booster tap constrained position, and hence phase angle, Quadrature Booster tap position, and more henceequitably the added phase chosen such that the current is shared between angle, is chosen such that the current is shared more equitably the parallel lines.

Au/your-requirements/products/ Projects/tier-2-projects/Flexible-Plug-and-Play-(FPP)/ProjectDocuments/Euro-TechCon-2013-Quadrature-booster-full-paperNov-2013.pdf WILSON TRANSFORMER COMPANY PTY LTD A Quadrature Booster consists of two separate three-phase transformers specially connected: a shunt connected unit on the Power Transformer Business Unit supply terminals S1,S2,S3 and a series connected unit on the 310 Springvale Road , Glen Waverley load terminals L1,L2,L3.

The Downham Market No.2 circuit is connected electrically in parallel to the Northwold No.1 circuit, but it is almost half the length of the Northwold No.1 circuit.

During peak export, the thermal capacity of the Downham Market No.2 circuit is reached before that of the two other circuits because the loads are unbalanced across the paralleled circuits.

The output of the CHP generator is managed by an existing automatic generator turndown scheme which monitors the loadings on the outgoing 33kV circuits, along with the status of circuit breakers.

Figure 7: Scatter graph showing recorded circuit loadings at Tap 11 The graphs in Figure 7 above were extrapolated by increasing CHP export by a further 10MW from 54MW to 64MW. Based on the extrapolated circuit load trend lines, it is projected that with the CHP export approaching 54MW the load on the Downham Market No.2 circuit would be approximately 23MW – which is 7MW below the winter static rating.

The increase in the load in the Downham Market No.2 circuit for the period 15 June 2014 to 23 July 2014 was because the Quadrature-booster was switched out of service and the Downham Market No.2 circuit placed on by-pass in order to carry out planned improvement works on the Quadrature-booster.

Figure 8 shows that the Downham Market No.2 circuit was loaded approximately twice as much load as was on each of the Northwold No.1 and Southery No.3 circuits for the period September 2012 to June 2013 as expected.

With an average of approximately 800A delivered by the CHP generator, the Downham Market No.2 circuit was loaded at approximately 400A with both the Northwold No.1 and Southery No.3 circuits carrying approximately 200A each on average.

Quadrature Booster Or Phase Shifting TX

Actually come to think of it I don’t know if I ever found out, or just meant to find out how a Delta to Wye shifts by 30o, because I certainly can’t remember now.

Ok, from what you said ” In an equilateral triangle, the bisector of any angle is perpendicular to and bisects the opposite side.

Phase B’s real current is perpendicular to phase AC’s voltage, and so on around the three vertices.

” I assume you chose Phase B just as an example phase from what you described I imagine it’d look something like this: Sorry but I haven’t used vector diagrams in ages, I perhaps understand less than you might expect, do you think you could elaborate on the picture a bit, because I wasn’t comfortable enough to label it myself, I was thinking the outside equilateral sides were the Delta phase voltage angles, but were the verticies? The series transformer on the side bucking the existing phase voltages? I still haven’t gotten past the mental block between where I am and understanding it.

Supplier Diversity

It includes contributions from senior supply chain experts and companies with world-class supplier diversity programmes, and provides real-life examples and best practices to embed supplier diversity beyond procurement.

It is an essential roadmap for any organisation looking to establish a world-class supplier diversity programme that brings innovation into the business, makes supply chains more competitive and flexible, and delivers socio-economic value while enhancing reputation.

Supplier Diversity Podcast: Dennis Ford, Supplier Diversity Awards Winner, SM Awards 2020 on promoting supplier diversity programs at Cummins Ltd. Click the link to listen to the podcast with Denis Ford.

Supplier Diversity Podcast: Mayank Shah, CEO of MSDUK on supporting ethnic minority businesses.

Supplier Diversity Podcast: Paul Harvey, on embedding supplier diversity at Marsh and McLennon Companies.

Supplier Diversity Podcast: Farida Gibbs, Chief Executive at Gibbs Hybrid on being an ethnic minority women-owned business.

2020 Best in Procurement Winners the South Australia Government share their supplier diversity project in the Department for Child Protection and their commitment to increasing commercial relationships with Aboriginal Community Controlled Organisations.

What Is Supplier Diversity And Why Is It Important?

In this guide, we’ll be covering what supplier diversity is, how it benefits both the purchaser and the community, types of diverse suppliers, and some general tips on building or overhauling a supplier diversity program.

Supplier Diversity programs encourage companies to procure from businesses owned by traditionally underrepresented or underserved people such as veterans, women, people of color, and members of other groups.

It’s essential to manage them with a robust supplier diversity program to ensure the most benefit for both the purchasing company and the broader community.

Many companies with supplier diversity programs measure indicators of this economic impact like jobs supported and money contributed to the economy to show how their diversity programs affect the world around them.

Whether starting or revamping a supplier diversity program, it’s important to treat it as more than an opportunity to get good publicity.

The best supplier diversity programs involve the buyer mentoring and actively engaging with its diverse suppliers at the first and second tiers.

Lack of supplier diversity rules for Tier 2, 3, or 4 suppliers.

Why You Need A Supplier-Diversity Program

A handful of socially conscious major companies have long played a role in addressing racial injustice through supplier diversity programs that promote an inclusive approach to procurement.

The Right Thing to Do. Supplier diversity programs can be part of a company’s efforts to maintain high moral and ethical standards.

Kris Oswold, vice president of global supplier diversity at UPS, told us that her company’s supplier diversity program, which started in 1992, grew out of its deepening desire to be more inclusive and do what is right.

In an interview, Terrez Thompson, vice president of global supply inclusion and diversity at Coca-Cola, highlighted the role that diversity programs play in fostering entrepreneurship in highly impacted minority groups.

Fifty-two percent of respondents to a survey conducted for UPS by Hootology, a specialized marketing and consumer insights research firm, said they want to work for a company that has a supplier diversity and inclusion program, according to Oswold.

In a 2019 study for Coca-Cola, Hootology, itself a diverse supplier, found that the individuals who were aware of Coca-Cola’s supplier diversity initiatives were 45% more likely to perceive the brand as valuing diversity, 25% were more likely to think favorably about the brand, and 49% were more likely to use Coca-Cola products.

Creating a supplier diversity program might be difficult in the near term in specialized markets where there are very few qualified suppliers such as defense.

Supply Chain Game Changer™

With all of the societal issues circulating around race, racism and discrimination it’s important to understand how this pertains to Supply Chain and what role Supply Chain plays in this arena.

“A Supplier Diversity program is a proactive business program which encourages the use of minority-owned, women owned, veteran owned, LGBT-owned , service disabled veteran owned, historically underutilized business, and Small Business Administration-defined small business concerns as suppliers.”

“It is not directly correlated with supply chain diversification, although utilizing more vendors may enhance supply chain diversification. Supplier diversity programs recognize that sourcing products and services from previously under-used suppliers helps to sustain and progressively transform a company’s supply chain, thus quantitatively reflecting the demographics of the community in which it operates by recording transactions with diverse suppliers.”

“Supplier Diversity is a strategic business process aimed at providing companies owned by aboriginal peoples and minorities an equal opportunity to become suppliers to major corporations across Canada and the US.”.

“It is an initiative by corporations to ensure they are being inclusive in their supply chain practices to suppliers of diverse backgrounds, while at the same time capitalizing on the opportunity for competitive advantage and community engagement that comes from working more closely with a broader range of aboriginal and minority suppliers.”

First most of the suppliers we were informed of were not production material suppliers but rather non-production, or indirect procurement spend or MRO candidates only.

Second most of the suppliers were extremely small and finding matches with what they supplied and what we needed was difficult to say the least.

Supplier Diversity

A metropolitan skyline and white text: “Global Supplier Diversity partnering with World Wide Technology.” Close-up of David Steward, a smiling man with dark hair, standing in front of a building next to a statue of a globe.

Who calls a company “World Wide Technology,” with five people, 4,000 square feet? What’s world-wide about this?

Jim stands beside the large metallic globe in front of the World Wide Technology building.

World Wide Technology simply put, builds complex technology infrastructure solutions for large, enterprise businesses, and we also write software that bring that infrastructure to life.

The relationship between JPMC and World Wide Technology goes back nearly eight years ago, when WWT was expanding onto the East Coast.

Being diverse means that you have the ability to not only understand various cultures, various technologies, but be able to adapt to things that you’re not accustomed to as well.

World Wide Technology gave us the opportunity – the first minority business to build a seven-story office tower.

Supplier Diversity

“Through our Supplier Diversity program, we aim to make meaningful contributions to the economic growth of diverse companies and communities. We value the innovation and fresh ideas that diverse businesses bring to the table, and we’re committed to providing resources that can help drive their development and success.”

HTML Editor Component *Contents may not have visible height.

Supplier Diversity Custom CSS and JS. HTML Editor Component *Contents may not have visible height.

Supplier Diversity: How To Overcome Four Key Obstacles

UPS, Target, Pacific Gas and Electric, and other leaders have been building more diverse supplier pools for decades, a move that benefits their bottom lines and reduces supplier turnover.

The company’s supplier diversity team holds business fairs at its Minneapolis headquarters that give diverse vendors an opportunity to present their products to Target’s buyers alongside traditional suppliers.

One of the key reasons supplier diversity initiatives flounder is that organizations underinvest in the capabilities required to support new or developing suppliers, including onboarding, risk mitigation, and mentoring.

Leadership teams seeking to build a more diverse supplier base typically target the Tier 1 supplier pool and don’t take the next step of increasing diversity among Tier 2 suppliers-or broadening the scope of their commitment to work with companies that may not have a minority owner but excel at diversity in hiring, leadership training, and organizational culture.

Leaders in supplier diversity implement a multiyear vision that reaches beyond Tier 1 suppliers.

These leaders integrate supplier diversity initiatives into the firm’s broader strategy, ensure organizational alignment, commit sufficient resources to build new capabilities, and look beyond the Tier 1 supply base to develop a deep and sustainable supplier ecosystem.

Many companies struggle with meeting their supplier diversity objectives, but leaders have learned how to overcome the obstacles.

Aurea Software

Two powerful tools that lead the way in document management and enterprise communication.

Better content creation and management tools from our BroadVision acquisition bring tremendous and immediate value to our customers.

A pioneer in document management and enterprise communication tools.

BroadVision provides document and knowledge management applications that companies use to communicate effectively within their organizations.

Quicksilver – Powerful document creation and management tools available that enables businesses to create and publish lengthy, complex documents in virtually any language and any format.

Advancing our knowledge management capabilities For Aurea, BroadVision and QuickSilver solutions simplify the creation and management of complex documents requiring version control, input from multiple sources, multi-format publishing and execution in multiple languages.

Aurea Portal Management and QuickSilver are part of our growing Unlimited library Discover our full suite of integrated solutions for creating truly transformative customer experiences across every channel.

BroadVision Stock Forecast, Price & News

BroadVision, Inc. develops, markets, and supports enterprise portal applications that enable companies to unify their e-business infrastructure and conduct interactions and transactions with employees, partners, and customers through a personalized self-service model.

The company offers business agility suite, a portal that provides personalized views of information and processes; commerce agility suite, an e-commerce system for transacting business on the Web; Clearvale, an enterprise social network solution; Clear, a human resources management system; QuickSilver, a publishing system for large and complex documents; and Vmoso, a cloud application for conducting virtual enterprise communications, mobile workgroup collaborations, and social business engagements.

It also provides frameworks that offer portal services for organizing and presenting information; commerce services for transacting business on the Web; process services for transforming people-intensive processes and collaborations into Web-based self-service applications; content services for managing Web content throughout its lifecycle; staging services for moving content from development environment to production environment; search for full-text and field searching of online content and referenced external files with relevance ranking; unified stream services for unification and integration of information; event driven services to deliver notifications through various messaging platforms; and migration services for data moving across platforms.

The company offers business consulting, implementation, integration and package, upgrade and migration, and performance tuning services; education, and support maintenance services; and Vmoso and Kukini developer toolkits, and Kona framework, as well as Vmoso Enterprise Transformation, a proprietary implementation approach for the Vmoso collaborative solution.

BroadVision, Inc. was founded in 1993 and is headquartered in Redwood City, California.

Broadvision

BroadVision is an international software vendor of self-service web applications for enterprise social software, electronic commerce, enterprise portals, and customer relationship management.

The company provides toolkit, framework, library for extending its products and services.

BroadVision was a pioneer in eCommerce in the 1990s, and its stock was highly valued during the dot-com bubble, reaching a split-adjusted high of over $20,000 per share in March 2000.

After the bubble burst, Broadvision struggled, and its stock was delisted from the Nasdaq for a period.

In 1995 its ecommerce services were introduced to the market and the company became public on Nasdaq in the next year.

During the next ten years, the company extended its market step by step, introducing Clear, Clearvale, Clearvale Second Floor Speaker Series, Clearvale PaasPort, and Clearvale Express.

Applications of the company include business agility suite, ecommerce agility suite for online shopping, Clearvale, Clear management system), QuickSilver, Kona framework, and eMerchandising Clearvale is BroadVision’s enterprise social networking platform available under a software as a service model.

Inbound Marketing Consultants

Digital marketing can be overwhelming, and not having a grasp on advancing digital technologies or the industry insight about ever-shifting algorithm trends, it’s easy to get lost in a sea of marketing strategy.

That’s why our mastermind marketing team employs customized data-driven marketing solutions that, simply put, work.

Technologies » Solutions » Enterprises

The world is evolving around us and no longer is technology a solution, it is an enabler of growth for positive progress.

Our solutions go beyond being integrative, they are holistic.

We partner with you on your journey to digital transformation; finding the right solutions for your business that will not only accelerate your organisations innovation, but optimize today’s evolving technology environment.

BROADVISION, INC.

Commences next step to restructure and sell business through implemen.

2020La Chine redémarre plus vite que prévu 2016GNW-NEWS : Die Experton Group positioniert BroadVision als Leader im Bereich Social Busine.

2011BROADVISION INC : BroadVision et Nextmodernity lancent un programme d’adoption Clearvale.

2021 List Of Top 15 Collaboration Software Tools

Collaboration software is a platform that enables team members to connect and work on projects from different locations and devices.

Confluence: A reliable collaboration and project management software built for teams in different fields, such as project management, IT, marketing, legal, and HR. The platform provides a collaborative workspace for teams while making it easy to plan, execute, and monitor projects.

Hiver: is a reliable email collaboration software built to help teams manage their inboxes like , , and right from Gmail.

We cannot emphasize enough the role collaboration software plays in maintaining a close-knit team.

Luckily, collaboration tools bring order to project tasks and team management.

Online collaboration software enables teams to work together in complete unison, thus, enhancing collaboration.

Why do you want to install a collaboration software? For small teams, a set of basic features such as chat, Instant Messaging, and conferencing tools might effectively boost productivity.

15 Best Collaboration Software Comparison

In this comparison of the best collaboration software, we’ll drill into the most important questions.

We’ll discuss which collaboration tools are best suited to which industries and company sizes.

Get ready for a deep dive into 15 of the best online collaboration solutions.

Choosing the best collaboration tools for your needs: key takeaways.

There are a handful of good project management and team collaboration software.

If you are a small enough team, some collaboration software offer free versions, like Flock, Podop or Wrike.

You use collaboration software to work together on tasks and manage projects, communicate via text voice or video, and share files.

The Best Online Collaboration Software For 2022

Collaboration apps are changing the way people work, and it’s about time.

A collaboration app is any piece of software that helps people get work done together.

Collaboration apps are a subcategory of productivity apps.

PCMag has three Editors’ Choice selections in that category, all of which have made it to this list of the best collaboration apps.

Basecamp belongs among the best multipurpose collaboration apps, too.

Todoist is the PCMag Editors’ Choice winner for to-do list apps, but it’s also a highly valuable collaboration tool.

Many collaboration apps have started adding kanban views so that you always have the option to work in kanban if you want.

2022 Reviews, Pricing, And Demos

Monday.commonday.commonday.com, an award-winning collaboration and project management platform, helps teams plan together efficiently and execute complex projects to deliver results on time.

ClickUpClickUpClickUp is a cloud-based collaboration and project management tool suitable for businesses of all sizes and industries.

SlackSlackSlack is a cloud-based project collaboration and team interaction tool designed to facilitate communication across organizations.

Software pricing tipsRead our Collaboration Buyers GuideSubscription modelsPer employee/per month: This model allows you to pay a monthly fee for each of your employees.

What is collaboration software?Common functionality of collaboration softwareBenefits of collaboration softwareWhat type of buyer are you?Market trends to understand.

Online collaboration software can help save on project costs by performing multiple functions that would ordinarily require several different tools to accomplish.

A small team that manages limited projects and has team members who prefer remote work, may want to consider a collaboration app that will help members communicate with each other and centralize information.

What Is Collaboration Software

The term collaboration software refers to a variety of applications that enable users to interact with each other, share tasks and achieve common goals.

In contrast to communication software, which primarily serves the exchange of messages, collaboration software explicitly serves the purpose of working together on tasks and projects.

Areas of application for collaboration software include agile project management, joint processing of files and documents, and special use cases such as idea management, innovation management and knowledge management.

The basic functionalities of collaboration software as well as the use of these tools within companies are described in this article.

12 Best Free & Paid Collaboration Software For 2022

Select the filters below to find the best collaboration software for your team’s needs.

Whiteboard collaboration: Brainstorm ideas together with your team using the whiteboard collaboration tool.

Microsoft Teams is a popular enterprise collaboration software.

Microsoft Teams is an affordable team collaboration software.

Chanty, like Slack, is primarily a messaging-based team collaboration software.

We’ve looked at the best collaboration software for team, project, and document collaboration.

You could Toggl Plan for project collaboration, Slack for team communication, and Notion as your document collaboration tools.

Collaborative Software

Collaborative software or groupware is application software designed to help people working on a common task to attain their goals.

As regards available interaction, collaborative software may be divided into: real-time collaborative editing platforms that allow multiple users to engage in live, simultaneous and reversible editing of a single file, and version control platforms, which allow separate users to make parallel edits to a file, while preserving every saved edit by every user as multiple files.

Collaborative software is a broad concept that overlaps considerably with computer-supported cooperative work.

The use of collaborative software in the work space creates a collaborative working environment.

Collaborative software relates to the notion of collaborative work systems, which are conceived as any form of human organization that emerges any time that collaboration takes place, whether it is formal or informal, intentional or unintentional.

Whereas the groupware or collaborative software pertains to the technological elements of computer-supported cooperative work, collaborative work systems become a useful analytical tool to understand the behavioral and organizational variables that are associated to the broader concept of CSCW. Douglas Engelbart first envisioned collaborative computing in 1951 and documented his vision in 1962, with working prototypes in full operational use by his research team by the mid-1960s, and held the first public demonstration of his work in 1968 in what is now referred to as “The Mother of All Demos.” The following year, Engelbart’s lab was hooked into the ARPANET, the first computer network, enabling them to extend services to a broader userbase.

Online collaborative gaming software began between early networked computer users.

Productivity Definition

Labor productivity may be further broken down by sector to examine trends in labor growth, wage levels, and technological improvement.

At the corporate level, productivity is a measure of the efficiency of a company’s production process, it is calculated by measuring the number of units produced relative to employee labor hours or by measuring a company’s net sales relative to employee labor hours.

The most commonly reported productivity measure is labor productivity published by the Bureau of Labor Statistics.

Gains in productivity can occur both in recessions and in expansions-as it did in the late 1990s-so one needs to take economic context into account when analyzing productivity data.

We simply need to divide the $1 million figure by 5,000 labor hours in order to get our productivity number: $20 in sales for each hour of labor.

What does productivity mean? Productivity is the level of efficiency in the production process.

What is productivity in the workplace? Productivity in the workplace refers simply to how much “Work” is done over a specific period of time.

Metalworking Machine Tools Supplier & Equipment Distributor

We are a single source machine tool distributor of metalworking machines, tooling supplies, robots and related manufacturing products and services.

More than just a machine tool dealer, we also have the knowledge and experience to provide the services your machine shop needs to achieve maximum productivity.

Productivity and MMT Productivity provide machine tools, tooling and supplies, industrial robots, and related equipment for manufacturing facilities to machine shops in Minnesota, North Dakota, South Dakota, Iowa, Nebraska and western Wisconsin as well as in Colorado, Utah, New Mexico, Idaho, Montana and Wyoming.

As top metalworking machine tool distributors, Productivity and MMT Productivity have been committed to helping companies implement innovative solutions to meet manufacturing challenges with superior results since 1968 and 1952, respectively.

Productivity Inc. Productivity Inc. is your single source supplier of metalworking machines, tools, accessories and robotic automation.

Productivity Inc provides exclusive CNC distribution of Haas Automation, Inc. metal forming machine tools.

We offer a full line of Haas CNC vertical and horizontal machining centers, CNC lathes, tool room machines, rotary tables, and 5C indexers through our Haas Factory Outlet.

Psychology Today

Productivity generally refers to the ability of an individual, team, or organization to work efficiently within that time in order to maximize output.

High productivity results from a mix of factors: motivation, personality, natural talent, training or education, environment, support from others, time management, and even luck.

Physical elements also play a role in fostering productivity: Exercise, healthy eating, and sufficient sleep can boost efficiency both in the short- and long-term.

An individual’s productivity hinges on mental energy and a sense of internal and external motivation.

There are countless ways for productivity to be derailed.

It takes time for the brain to disengage from one set of tasks and to commit to another, so switching between many tasks at once will slow overall productivity.

Technology poses an endless supply of immediate distractions as well; avoiding them as much as possible should help fuel productivity.

Productivity

There are many different definitions of productivity and the choice among them depends on the purpose of the productivity measurement and/or data availability.

The key source of difference between various productivity measures is also usually related to how the outputs and the inputs are aggregated into scalars to obtain such a ratio-type measure of productivity.

Historically, productivity has improved through evolution as processes with poor productivity performance are abandoned and newer forms are exploited.

Drivers of productivity growth for creative and knowledge workers include improved or intensified exchange with peers or co-workers, as more productive peers have a stimulating effect on one’s own productivity.

The matter is subject to a continuing debate that has grown beyond questioning whether just computers can significantly increase productivity to whether the potential to increase productivity is becoming exhausted.

The OECD publishes an annual Compendium of Productivity Indicators that includes both labor and multi-factor measures of productivity.

“Forecasting the Malmquist productivity index,” Journal of Productivity Analysis, Springer, vol.

What Is Productivity, And How Do You Measure It?

Productivity is good for individuals, companies and countries, according to economists.

At its simplest, labour productivity is the amount of output per worker.

The productivity of a factory worker making footballs, for example, could be measured by how many footballs they make in one hour.

It is worth the effort as productivity is an important measure of a country’s economic performance.

According to research from the Chartered Management Institute, it found that an “Always on” work culture of ever increasing hours and rocketing stress levels could be one of the driving forces behind the UK’s poor productivity.

In most OECD countries, the drop in productivity has been particularly marked in those industries where new digital and technological innovations were expected to generate productivity dividends, such as in the information, communication, finance and insurance sectors.

Many challenges lie ahead for the countries lagging behind on productivity, and economists have been debating this question of how to improve productivity for years.

What Is Productivity? A Proven Guide To Improve Your Productivity

Min read. Welcome to this productivity guide.

Too often, we try to improve productivity without knowing what it is.

Second, I share tested and proven ways to improve your productivity.

If a person, manager, CEO, leader, wants to improve collective productivity; one must improve personal productivity.

Simply improve your personal productivity and see what effects it has on your work, energy, mind, rewards, happiness, etc.

What’s the first thing you want to improve when it comes to productivity? You can come back to this guide as much as you like.

The funny thing is that the best books I’ve read about productivity are not productivity books.

The Productivity Guide: My Best Productivity And Time-Management Tips

Productivity is a measure of efficiency of a person completing a task.

We often assume that productivity means getting more things done each day.

Productivity is getting important things done consistently.

My Top Productivity Strategies Eliminate Time Wasting Activities by Using the Eisenhower Box: This simple decision matrix will help you take action, organize tasks, and get more done.

The Ivy Lee Method: The Daily Routine Experts Recommend for Peak Productivity: This productivity strategy is straightforward: Do the most important thing first each day.

Most productivity strategies focus on short-term efficiency: how to manage your to-do list effectively, how to get more done each morning, how to shorten your weekly meetings, and so on.

Want more great books on productivity? Browse my full list of the best productivity books.

MicroMain Corporation

Since 1991, MicroMain Corporation has been solely in the business of providing maintenance and facility management software and services to organizations worldwide.

Our goal is to provide simply everything to manage any facility-simply.

With our easy-to-use software, customers streamline maintenance operations, improve facility management, simplify capital planning, and reduce costs.

MicroMain Corporation

MicroMain is an industry leading provider of facility and maintenance management software to organizations around the world.

MicroMain’s award-winning CMMS software helps companies effectively manage their maintenance tasks and lower costs resulting in greater productivity and profits.

Pembrolizumab

As of 2019, pembrolizumab is used via intravenous infusion to treat inoperable or metastatic melanoma, metastatic non-small cell lung cancer in certain situations, as a first-line treatment for metastatic bladder cancer in patients who cannot receive cisplatin-based chemotherapy and have high levels of PD-L1, as a second-line treatment for head and neck squamous cell carcinoma, after platinum-based chemotherapy, for the treatment of adult and pediatric patients with refractory classic Hodgkin’s lymphoma, and recurrent locally advanced or metastatic esophageal squamous cell carcinoma.

For NSCLC, pembrolizumab is a first-line treatment if the cancer overexpresses PD-L1, a PD-1 receptor ligand, and the cancer has no mutations in EGFR or in ALK; if chemotherapy has already been administered, then pembrolizumab can be used as a second-line treatment, but if the cancer has EGFR or ALK mutations, agents targeting those mutations should be used first.

In July 2021, the U.S. FDA approved pembrolizumab for high-risk, early-stage, triple-negative breast cancer in combination with chemotherapy as neoadjuvant treatment, and then continued as a single agent as adjuvant treatment after surgery.

If a person is taking corticosteroids or immunosuppressants, those drugs should be stopped before starting pembrolizumab because they may interfere with pembrolizumab; they may be used after pembrolizumab is started to deal with immune-related adverse effects.

On 2 October 2015, the US FDA approved pembrolizumab for the treatment of metastatic non-small cell lung cancer in patients whose tumors express PD-L1 and who have failed treatment with other chemotherapeutic agents.

In June 2019, the US FDA granted accelerated approval to pembrolizumab for those with metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy and at least one other prior line of therapy, and the FDA approved pembrolizumab for the first-line treatment of patients with metastatic or unresectable recurrent head and neck squamous cell carcinoma.

As of May 2016, pembrolizumab was in Phase IB clinical trials for triple-negative breast cancer, gastric cancer, urothelial cancer, and head and neck cancer and in Phase II trial for TNBC. At ASCO, in June 2016, Merck reported that the clinical development program was directed to around 30 cancers and that it was running over 270 clinical trials and had four registration-enabling studies in process.

NCBI Bookshelf

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma.

Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomized dose-comparison cohort of a phase 1 trial.

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.

Pembrolizumab versus ipilimumab in advanced melanoma.

Pembrolizumab for the treatment of non-small-cell lung cancer.

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma: a randomised, controlled, phase 2 trial.

Lancet Oncol 2015; 16: 908-18.Abdel-Rahman O, El Halawani H, Fouad M. Risk of elevated transaminases in cancer patients treated with immune checkpoint inhibitors: a meta-analysis.

Pembrolizumab

On August 5, 2016, the U. S. Food and Drug Administration granted accelerated approval to pembrolizumab for the treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma with disease progression on or after platinum-containing chemotherapy.

Patients received intravenous pembrolizumab 10 mg/kg every 2 weeks or 200 mg every 3 weeks.

Among the 28 responding patients, 23 had responses of 6 months or longer.

Safety data was evaluated in 192 patients with HNSCC receiving at least one dose of pembrolizumab 10 mg/kg every 2 weeks or 200 mg every 3 weeks.

Adverse reactions occurring in patients with HNSCC were similar to those occurring in patients with melanoma or NSCLC, with the exception of an increased incidence of facial edema and new or worsening hypothyroidism.

As a condition of the accelerated approval, Merck is required to conduct a multicenter, randomized trial establishing the superiority of pembrolizumab over standard therapy to verify and describe the clinical benefit of pembrolizumab.

Merck has an ongoing multicenter, randomized trial in patients with recurrent or met HNSCC with disease progression on or after platinum-containing chemotherapy with a primary endpoint of overall survival.

Pembrolizumab

The development of the cytotoxic T-lymphocyte-associated protein 4 inhibitor ipilimumab and its approval in 2011 for the treatment of metastatic melanoma has heralded a new era in immuno-oncology.

Subsequently, novel agents against the programmed death receptor 1/programmed death receptor ligand 1 axis have shown significant activity in melanoma and a variety of other tumor types.

Pembrolizumab was the first anti-PD-1 antibody to be approved by the US Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma with disease progression following ipilimumab, and if BRAF mutation positive, a BRAF inhibitor.

Pembrolizumab has also received breakthrough status for the treatment of EGFR mutation-negative, ALK rearrangement-negative non-small cell lung cancer that has progressed on or following platinum-based chemotherapy.

There remain a number of pivotal trials in progress to further evaluate the optimal use of pembrolizumab alone and in combination for melanoma, NSCLC, and other tumor types.

In this article, we review the efficacy and toxicity profile of pembrolizumab and evaluate its future development.

Keywords: Immune checkpoint blockade; Lung cancer; Melanoma; Pembrolizumab; Programmed death receptor 1; Programmed death receptor ligand 1.

Cancer Research UK

You have pembrolizumab for as long as it works and the side effects are not too bad. You usually have it for up to 2 years, but some people might have treatment for longer than 2 years.

Depending on your cancer type, you might have pembrolizumab on its own or with other cancer treatments.

Early treatment can help manage side effects better.

You might lose your appetite for various reasons when you are having cancer treatment.

Let your doctor or nurse know if you have pain during or after treatment.

The coronavirus vaccine – talk to your doctor or pharmacist about the best time to have it in relation to your cancer treatment.

This is to help lower your risk of getting COVID-19 while having cancer treatment and until your immune system recovers from treatment.

KEYTRUDA®

KEYTRUDA is a medicine that may treat certain cancers by working with your immune system.

KEYTRUDA can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work.

Do not breastfeed during treatment with KEYTRUDA and for 4 months after your final dose of KEYTRUDA. Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Common side effects of KEYTRUDA when used alone include feeling tired; pain, including pain in muscles; rash; diarrhea; fever; cough; decreased appetite; itching; shortness of breath; constipation; bones or joints and stomach-area pain; nausea; and low levels of thyroid hormone.

Common side effects of KEYTRUDA when given with certain chemotherapy medicines include feeling tired or weak; nausea; constipation; diarrhea; decreased appetite; rash; vomiting; cough; trouble breathing; fever; hair loss; inflammation of the nerves that may cause pain, weakness, and paralysis in the arms and legs; swelling of the lining of the mouth, nose, eyes, throat, intestines, or vagina; mouth sores; headache; weight loss; stomach-area pain; joint and muscle pain; and trouble sleeping.

Common side effects of KEYTRUDA when given with chemotherapy and bevacizumab include tingling or numbness of the arms or legs; hair loss; low red blood cell count; feeling tired or weak; nausea; low white blood cell count; diarrhea; high blood pressure; decreased platelet count; constipation; joint aches; vomiting; urinary tract infection; rash; low levels of thyroid hormone; and decreased appetite.

Common side effects of KEYTRUDA when given with axitinib include diarrhea; feeling tired or weak; high blood pressure; liver problems; low levels of thyroid hormone; decreased appetite; blisters or rash on the palms of your hands and soles of your feet; nausea; mouth sores or swelling of the lining of the mouth, nose, eyes, throat, intestines, or vagina; hoarseness; rash; cough; and constipation.

Pembrolizumab Uses, Side Effects & Warnings

Pembrolizumab is often given when the cancer has spread to other parts of the body or cannot be treated with surgery or radiation, or when other cancer treatments did not work or have stopped working.

For some types of cancer, pembrolizumab is given only if your tumor tests positive for “PD-L1”, or if the tumor has been tested for a specific genetic marker.

Pembrolizumab can cause serious or life-threatening side effects.

You will need frequent medical tests to help your doctor determine if it is safe for you to keep receiving pembrolizumab.

Your doctor will perform a blood test to make sure pembrolizumab is the right treatment for your condition.

Call your doctor for instructions if you miss an appointment for your pembrolizumab injection.

Pembrolizumab strengthens your immune system to help your body fight against cancer cells.

Combination Therapy In Combating Cancer

Prevention of cancer in the next millennium: Report of the Chemoprevention Working Group to the American Association for Cancer.

Cha HY, Lee BS, Chang JW, Park JK, Han JH, Kim YS, Shin YS, Byeon HK, Kim CH. Downregulation of Nrf2 by the combination of TRAIL and Valproic acid induces apoptotic cell death of TRAIL-resistant papillary thyroid cancer cells via suppression of Bcl-xL. Cancer Lett.

Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.

Semenza GL. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.

Phase II trial of gefitinib in combination with bevacizumab as first-line therapy for advanced non-small cell lung cancer with activating EGFR gene mutations: the Okayama Lung Cancer Study Group Trial 1001.

Hu Y, Bebb G, Tan S, Ng R, Yan H, Sartor JR, Mayer LD, Bally MB. Antitumor efficacy of oblimersen Bcl-2 antisense oligonucleotide alone and in combination with vinorelbine in xenograft models of human non-small cell lung cancer.

Wang T, Narayanaswamy R, Ren H, Torchilin VP. Combination therapy targeting both cancer stem-like cells and bulk tumor cells for improved efficacy of breast cancer treatment.

ScienceDirect Topics

A small residual role for monotherapy remains, particularly in patients who are more likely to have a negative response to therapy, patients suspected of having PVOD/PCH, and patients older than 75 years or with multiple risk factors for heart failure with preserved ejection fraction.

Patients with very mild disease and stable patients with a low-risk profile while on long-term monotherapy may also be appropriate candidates for continued monotherapy.

98.The AMBITION clinical trial published in 2015 set the standard for initiating dual therapy in treatment naive patients with PAH.99 The trial was composed of three arms comparing the initiation of ambrisentan monotherapy, tadalafil monotherapy, and ambrisentan plus tadalafil up-front dual therapy with a primary end point of time to first clinical failure.

In the pivotal GRIPHON trial, the majority of patients enrolled were already taking background PAH medication, with 15% on an ERA alone, 32% on a PDE5I alone, and 33% taking both an ERA and a PDE5I.97 Additional positive studies that included large numbers of patients receiving combination therapy are shown ineTables 84.2.

Medical TherapyMedical therapy may be elected in select patients, particularly in patients with BMAH or PPNAD, in patients who are poor surgical candidates, and in patients with CS due to metastatic adrenal cortical carcinoma.

Coronary RevascularizationMedical therapy alone is the preferred treatment in patients with stable CAD. The two indications for coronary revascularization in patients with CAD are prolongation of life and relief of unacceptable symptoms despite optimal medical management.

A randomized trial of 2287 patients with stable CAD and myocardial ischemia treated with optimal medical therapy alone or optimal medical therapy plus percutaneous coronary intervention showed at 4.6-year follow-up no significant difference in death, MI, or other major cardiovascular events.

Combination Therapy

Broadly, the effects of the combined treatment are those of the individual modalities.

The combination of US with IF appears to give rise to less adverse treatment effects than are associated with the combination of US with Diadynamic Currents, or other electrical stimulations.

In summary, it would appear that by combining the two treatment modalities, none of the individual effects of the treatments are lost, but the benefit is that lower treatment intensities can be used to achieve the same results, & there are additional potential benefits in terms of diagnosis & treatment times.

Treatment Notes A) Diagnostic Use of Combined Therapy It is suggested that a continuous US output of 0.5W/cm2 should be used for this procedure, though numerous practitioners do claim to have achieved significant results with lower intensities.

B) Treatment with Combined Therapy Diagnostic and therapeutic uses of Combination Therapy need not be used together.

When the required treatment times are similar, the combination of the modalities can save time and effort.

It is important to observe the safe & effective US treatment technique during combined treatment i.e. always using a moving treatment head, maintain effective contact, & maintain the perpendicular relationship between the treatment head & the patients skin whenever possible.

What Is Combination Therapy?

For well over half a century, physicians have had three main types of cancer treatments in their arsenal: surgery, radiation therapy, and chemo-, or drug, therapy.

As a general rule, solid tumors are usually treated by surgery, if confined to the site they started in, and/or radiation therapy to remove or reduce the tumor, followed by chemotherapy to eliminate any remaining tumor cells.

In many cases, combination therapy not only increases the chances of a cure or long-term remission, but also reduces damage to vital organs and tissues more than a single approach.

Where surgical amputation used to be the only treatment, the combination of radiation therapy and chemotherapy are often able to destroy the cancer without necessitating a loss of the limb.

Early-stage breast cancer often can be treated by removal of the tumor and surrounding tissue followed by radiation therapy.

One type of therapy can sometimes make a tumor more vulnerable to a second type.

Certain chemotherapy drugs, for example, can increase tumors’ vulnerability to radiation therapy.

Combination Therapy

Contents loading…. Editors loading…. Categories loading…. When refering to evidence in academic writing, you should always try to reference the primary source.

That is usually the journal article where the information was first stated.

In most cases Physiopedia articles are a secondary source and so should not be used as references.

Physiopedia articles are best used to find the original sources of information.

If you believe that this Physiopedia article is the primary source for the information you are refering to, you can use the button below to access a related citation statement.

Combination Therapies For Depression

Until recently, doctors prescribed an antidepressant medication from only a single class of drugs, one medication at one time.

Research now suggests that taking antidepressants from multiple classes may be the best way to treat MDD. On its own, bupropion is very effective at treating MDD, but it may also be used with other medications for depression that’s difficult to treat.

Bupropion is one of the most commonly used combination therapy medications.

Mirtazapine hasn’t been studied in depth as a combination medication.

They can be used alone, but they may also be used in combination with antidepressant medications.

Still, many doctors will begin treatment with a single antidepressant medication.

If the medication isn’t working as desired after a trial period – usually about 6 to 8 weeks – your doctor may wish to change medications or add a medication to see whether the combination helps.

Combination Chemotherapy: History, Benefits, And Risks

Combination chemotherapy is the use of more than one medication at a time to treat cancer.

Since chemotherapy drugs affect cancer cells at different points in the cell cycle, using a combination of drugs increases the chance that all of the cancer cells will be eliminated.

History of Combination Chemotherapy The use of combination chemotherapy to treat cancer was inspired in the 1960s when scientists wondered whether the approach to treating tuberculosis-using a combination of antibiotics to reduce the risk of resistance-would work for treating cancer as well.

In the 1970s, combination chemotherapy was found to be more effective than single drugs for people with lung cancer, as well as more effective than “Sequential chemotherapy”-i.e., using chemotherapy drugs one after the other.

When chemotherapy is used along with immunotherapy, benefits may go beyond using the combination of drugs.

Just as a combination of antibiotics may be used in case a particular bacteria is resistant to one of the medications, using two or more chemotherapy drugs reduces the risk that a tumor will be resistant to the treatment.

Combination chemotherapy can sometimes work to extend life, reduce the risk of cancer recurrence, and/or improve the results from immunotherapy.

Programmed Cell Death Protein 1 On Natural Killer Cells: Fact Or Fiction?

Programmed cell death protein 1 has become one of the most investigated targets for cancer immunotherapy.

Programmed cell death protein 1 is induced after T cells are activated and serves as a marker of activation that provides inhibitory signals to T cells after engagement of its ligand, programmed death ligand 1.

Interestingly PD-1 blockade can induce responses in various cancers with low expression of major histocompatibility complex class I, necessary for cytotoxic CD8+ T cell recognition, suggesting enhanced cytolytic activity by CD4+ T cells or effector cells capable of cytotoxicity independently of MHC.NK cells are cytotoxic lymphocytes that can eliminate virally infected cells and tumors using cytotoxicity mechanisms similar to CD8+ T cells, but that do not require recognition of MHC. Using deductive reasoning from the “Missing self” hypothesis, blocking PD-1 on NK cells may augment antitumor effects for tumors that are refractory to T cell treatments due to low MHC expression.

RT-PCR and Western blot data have shown, using both human NK cell lines and purified NK cells from healthy donors, that resting NK cells and IL-2-stimulated NK cells harbor a cytoplasmic pool of PD-1 mRNA and protein despite low surface-expression levels.

More data, specifically from patients given anti-PD-1 who are deficient in T cells or chimeric antigen receptor-modified NK cells that are engineered as PD-1 deficient, will ultimately inform the debate on whether PD-1 expression on NK cells is fact or fiction.

Programmed cell death protein-1/programmed death-ligand 1 blockade enhances the antitumor efficacy of adoptive cell therapy against non-small cell lung cancer.

Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers.

Programmed Cell Death Protein 1

Programmed cell death protein 1, also known as PD-1 and CD279, is a protein on the surface of T and B cells that has a role in regulating the immune system’s response to the cells of the human body by down-regulating the immune system and promoting self-tolerance by suppressing T cell inflammatory activity.

PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.

PD-L1 protein is upregulated on macrophages and dendritic cells in response to LPS and GM-CSF treatment, and on T cells and B cells upon TCR and B cell receptor signaling, whereas in resting mice, PD-L1 mRNA can be detected in the heart, lung, thymus, spleen, and kidney.

Reduced T cell proliferation was also correlated with attenuated IL-2 secretion and together, these data suggest that PD-1 negatively regulates T cell responses.

Consistent with a role in negatively regulating CD8+ T cell responses, using an LCMV viral vector model of chronic infection, Rafi Ahmed’s group showed that the PD-1-PD-L1 interaction inhibits activation, expansion and acquisition of effector functions of virus specific CD8+ T cells, which can be reversed by blocking the PD-1-PD-L1 interaction.

Anti-CTLA4 treatment leads to an enhanced antigen specific T cell dependent immune reaction while anti-PD-1 appears to reactivate CD8+ T cells ability to lyse cancer cells.

The authors hypothesized that the higher levels of CD8+ T cell infiltration was due to anti-CTLA-4 inhibited the conversion of CD4 T cells to T regulator cells and further reduced T regulatory suppression with anti-PD-1.

Programmed Cell Death Protein-1/Programmed Death-Ligand-1 Axis In Hepatocellular Carcinoma: Prognostic And Therapeutic Perspectives

Hepatocellular carcinoma is the most common primary neoplasia of the liver.

As opposed to other cancer entities immunotherapy has just recently gained popularity in HCC. Among various immunotherapy approaches, programmed cell death protein-1, and its ligand programmed death receptor ligand-1 axis became one of the most promising pathway of the decade.

The scientific interest in PD-1/PD-L1 axis is definitely justified due to: ability to detect PD-L1 expression in patients that underwent resection for HCC with prognostic values; the role of serum PD-L1 as a tool to identify early recurrences and to monitor treatment outcome; PD-1/PDL1 is a highly targetable pathway, with possible predictive markers, and with high clinical applicability that might help us in selecting a subgroup of HCC patients who are most likely to benefit from PD-1/PD-L1 inhibitors.

In this review we will first discuss the prognostic role of PD-1/PD-L1 as a bio-marker in various clinical scenarios.

Afterwards we will critically analyse the recently published trials with PD-1/PD-L1 inhibitors in HCC either alone or in combination with other treatment modalities.

The strengths and limits of PD-1/PD-L1 axis in both prognosis and therapy of HCC will be highlighted.

Keywords: Checkpoint inhibitors; Hepatocellular carcinoma; Immunotherapy; Ligand programmed death-ligand-1; Programmed cell death protein-1.

Programmed Cell Death Protein 1

Programmed cell death protein 1 is a protein that is preferentially expressed in the body’s immune B, T, and natural killer cells.

PD-1 is a transmembrane protein that binds to other proteins known as programmed death-ligand 1 and programmed death-ligand 2, which are members of a family of co-inhibitory/co-stimulatory molecules, known as B7. Taken together, PD-L1 and PD-L2 participate in antigen presentation and are expressed by a variety of cell types.

Although the molecular mechanisms of action are poorly understood, PD-1, when engaged with its PD-L1/2 receptor, interferes strongly with the signal transduction of the T cell receptor.

T cell functions can be enhanced by interfering with the signal transduction of PD-1.

PD-1 and T cell activation and peripheral tolerance.

In the midst of this regulation, PD-1 interacts with its PD-L1/2 ligands to send signals either directly or reversed to the cell expressing PD-1 or a cell expressing its ligands, respectively.

In addition to the aforementioned intended consequences, PD-1 is vital in the promotion of regulatory T cell development and the inhibition of self-reactive T cells, which have significant potential to be pathogenic.

Institut National De La Statistique Et Des Études Économiques

L’Institut national de la statistique et des études économiques est chargé de la production, de l’analyse et de la publication des statistiques officielles en France, depuis 1946.

De la loi de finances du 27 avril 1946 , sous le gouvernement provisoire, qui créent l’Institut national de la statistique et des études économiques pour la métropole et la France d’outre-mer, remplaçant le Service national des statistiques qui avait été créé par le régime de Vichy.

1996 : ouverture du Centre de formation de l’Insee Libourne en Gironde et installation de l’École nationale de la statistique et de l’analyse de l’information Bruz.

Parmi les projets les plus importants de l’Insee figurent la mise en place depuis le du nouveau recensement de la population française, devenu annuel avec renouvellement partiel, et le programme de refonte des statistiques annuelles d’entreprises, visant mettre en place la nouvelle enquête sectorielle annuelle auprès des entreprises françaises dès 2009, afin de répondre aux exigences statistiques européennes.

Les enquêtes annuelles Cadre de vie et sécurité produites conjointement avec l’Observatoire national de la délinquance et des réponses pénales et le Service statistique ministériel de la sécurité intérieure jusqu’à fin 2020, ou au plus tard en 2021, date laquelle l’INSEE en cessera la production pour des raisons budgétaires.

L’École nationale de la statistique et de l’administration économique, assurant la formation des administrateurs de l’Insee, ainsi que des ingénieurs spécialisés dans le domaine de la statistique, de l’économie et de la finance ;.

La lettre de mission adressée par le président Sarkozy le 11 juillet 2007 la ministre de l’Économie, des Finances et de l’Emploi, Christine Lagarde, déclarait : Vous engagerez parallèlement une réflexion sur notre appareil statistique, notamment l’indice des prix et les chiffres du chômage, pour que les statistiques utilisées par le gouvernement pour définir sa politique présentent toutes les garanties et reflètent réellement la réalité vécue par les Français .

🔎 Institut National De La Statistique Et Des Études Économiques

L’Institut national de la statistique et des études économiques est l’institut national de statistique français.

Il est chargé de la production et de l’analyse des statistiques officielles en France.

Organiser et exploiter les recensements de la population et publier les différents chiffres de population en France.

L’INSEE gère les codes qui servent identifier les communes ainsi que certaines nomenclatures, comme la nomenclature d’activités françaises, qui sert notamment coder l’activité principale exercée par une entreprise ou un établissement, ou la nomenclature des catégories socio-professionnelles,…. L’INSEE assure également la diffusion et l’analyse des informations statistiques.

Une grande école, l’École nationale de la statistique et de l’administration économique, assurant la formation des administrateurs de l’INSEE, ainsi que des ingénieurs spécialisés dans le domaine de la statistique, de l’économie et de la finance.

L’École nationale de la statistique et de l’analyse de l’information, école agréée, qui est en même temps une école d’ingénieur formant des spécialistes de l’analyse de l’information.

C’est la loi de finances du 27 avril 1946 qui crée l’Institut national de la statistique et des études économiques pour la métropole est la ville principale…) et la France d’outre-mer.

Institut National De La Statistique Et Des Etudes Economiques

Institut National de la Statistique et des Etudes Economiques.

L’Institut national de la statistique et des études économiques collecte, produit, analyse et diffuse des informations sur l’économie et la société françaises.

Elles leur permettent d’enrichir leurs connaissances, d’effectuer des études, de faire des prévisions et de prendre des décisions.

Pour satisfaire ses utilisateurs, l’Insee est l’écoute de leurs besoins et oriente ses travaux en conséquence en poursuivant un objectif principal : éclairer le débat économique et social.

Les fichiers nominatifs diffusés ici ne sont pas des fichiers aisément manipulables pour des calculs statistiques et ne sont actualisés que tous les mois.

La géolocalisation des établissements du répertoire Sirene, pour les études statistiques est mise disposition des utilisateurs.

Les taux d’activité des hommes et des femmes entre 1975 et 2020.

Institut National De La Statistique Et Des Études Économiques

The National Institute of Statistics and Economic Studies, abbreviated INSEE, is the national statistics bureau of France.

The INSEE was created in 1946 as a successor to the Vichy regime’s National Statistics Service.

The INSEE is responsible for the production and analysis of official statistics in France.

Eurostat uses INSEE statistics in combination with those of other national statistical agencies to compile comparable statistics for the European Union as a whole.

INSEE numbers are national identification numbers given to people.

The new organization was called the SNS or National Statistics Service.

The SNS was finally transformed into the INSEE by the law of 27 April 1946, The National Institute of Statistics and Economic Surveys for the metropolis and overseas France.

Institut National De La Statistique Et Des Études Économiques

Institut national de la statistique et des études économiques – SIG Politique de la Ville.

L’Institut national de la statistique et des études économiques est une direction générale du ministère de l’Économie, de l’Industrie et de l’Emploi.

L’Insee collecte, produit, analyse et diffuse des informations sur l’économie et la société française.

Il conduit des recensements et des enquêtes, il gère des bases de données et exploite aussi des sources administratives.

En 1991, l’Insee crée la Mission Villes pour mieux répondre aux besoins d’informations statistiques et d’études formulés par les acteurs de la politique de la ville.

L’Insee produit aujourd’hui, partir du recensement notamment, des indicateurs sur les populations des quartiers en difficulté, leurs logements et leurs activités dans le but d’aider l’élaboration de réponses adaptées aux besoins des habitants.

Indicateurs des RégionsIndicateurs des DépartementsIndicateurs des Contrats urbains de cohésion sociale Indicateurs des Zones urbaines sensiblesIndicateurs des Zones franches urbaines.

Institut National De La Statistique Et Des Études Économiques

L’Institut national de la statistique et des études économiques est chargé de rassembler, structurer les données dans des domaines aussi variés allant de la production des biens et services la cohésion sociale en passant par l’emploi et le chômage, les prix et les salaires, l’innovation et la création d’entreprise.

Le STATEC est aussi un bureau d’études ayant pour objectif d’analyser statistiquement les données récoltées en vue d’établir des prévisions micro et macro économiques.

Il a une double mission : d’une part, celle de collecter et, d’autre part, celle d’étudier, d’analyser, de modéliser les données de manière comprendre les phénomènes économiques et sociaux.

Institut national de la statistique et des études économiques.

L’Institut National De La Statistique Et Des Études Économiques

La Bibliothèque de la direction générale de l’Institut national de la statistique et des études économiques est une bibliothèque spécialisée de haut niveau dans les domaines économique, démographique, statistique et social, au caractère historique et international exceptionnel, relativement méconnue du public et des professionnels.

Il développe aussi une activité de conseil dans les régions ; – la coordination du système statistique public français : l’INSEE assure la cohérence de l’ensemble des travaux statistiques de tous ministères et organismes statistiques publics ; – l’enseignement supérieur : l’INSEE dirige le groupe des écoles nationales d’économie et statistique ; – les relations internationales : l’INSEE collabore aux travaux statistiques européens et internationaux et apporte son concours de nombreux services statistiques étrangers.

Située au sein de la Direction de la diffusion et de l’action régionale, la bibliothèque dépend de la division Documentation, qui a pour mission d’animer le système documentaire de l’INSEE. En effet, outre la bibliothèque centrale, il existe la DG huit unités de documentation, appelées relais documentaires, d’autres directions et départements spécialisés, comme la bibliothèque de la coopération, la bibliothèque de l’ENSAE, la documentation de la direction des statistiques d’entreprises, avec lesquels la bibliothèque coopère et collabore.

De même il existe dans chaque direction régionale une cellule documentation, chargée de répondre aux besoins des agents de ces unités régionales, qui fait appel régulièrement aux ressources de la bibliothèque centrale de la DG. Il est bien clair que le système documentaire décrit rapidement ici ne concerne pas la diffusion tous les publics des statistiques et des études produites par l’INSEE, en particulier les données de type conjoncturel.

La bibliothèque a le quasi-monopole des acquisitions au sein de la DG. Mais l’initiative des commandes se trouve partagée entre elle-même et les utilisateurs appartenant aux différents services de la DG. Tous, l’exception du département de l’informatique pour la documentation technique doivent transmettre leurs besoins, l’exception des demandes de publications récentes de l’INSEE, qui sont servies par une autre unité de la DG, au conservateur de la bibliothèque, qui décide, en fonction de la raison et de l’intérêt de la demande, ainsi que des possibilités budgétaires, d’acquérir ou non tel ou tel document.

La bibliothèque de la direction générale a été constituée en 1946-1951 par la réunion des fonds des quatre services suivants : – la Statistique générale de la France, 1801-1812 puis 1835-1941 ; – le Service national de la statistique, 1941-1946 ; – le Service des économies étrangères du ministère de l’Economie nationale ; – le fonds économique du Centre de documentation économique de la Bibliothèque nationale.

Les fonds se composent plus particulièrement de trois types de documents : – des séries statistiques : ce sont des publications de périodicité annuelle ou supra-annuelle constituées de tableaux chiffrés, avec peu ou pas d’analyses et de commentaires, portant sur des sujets essentiels : annuaires statistiques, recensements, rapports annuels de la banque centrale, statistiques du commerce extérieur, mais aussi statistiques agricoles, de production ou d’entreprises, de la santé, du système éducatif, des transports, etc.

EBARA CORPORATION

Since its foundation in 1912 as a pump manufacturer, EBARA has continued to think about the future of people, society, and the environment through manufacturing.

Today, we meet our customers’ needs in five businesses, namely our Pumps Business, Compressors and Turbines Business, Chillers Business, Environmental Plants Business, and Precision Machinery Business.

By supporting the social infrastructure that is essential to everyday life and to industry throughout the world in each of our business domains, the EBARA Group will contribute to solutions to environmental and energy issues and to the development of advanced technologies.

Ebara Corporation

Ebara Corporation is a publicly traded manufacturing company based in Tokyo, Japan which makes environmental and industrial machinery such as pumps and turbines.

It is the owner of the Elliott Company in the United States and Sumoto S.r.

Fluid Machinery & Systems Company, which produces: Pumps: standard and engineered pumps and pumping system engineering.

Turbines: Gas and steam turbines of various sizes, including micro gas turbines.

Precision Machinery Company which produces: CMP, Plating, and Cleaning systems.

Environmental Engineering Company, which produces: Water treatment and sewage and industrial wastewater systems.

Wiki collection of bibliographic works on Ebara Corporation.

Instrument Transformers: GE Grid Solutions

GE is an industry leader in the design and manufacturing of high, medium and low voltage instrument transformers.

With more than 100 years of experience, GE offers a broad array of standard and high accuracy models for revenue metering and system protection applications.

The portfolio of instrument transformers ranges from low voltage at 600 V suitable for industrial and high accuracy revenue metering, all the way up to high voltage at 1,200 kV. The portfolio also includes line traps and digital instrument transformers.

Instrument Transformers

When used for protection purposes, the instrument transformer outputs must accurately represent the transmission line values during both steady-state and transient conditions.

These critical signals provide the basis for circuit-breaker operation under fault conditions, and as such are fundamental to network reliability and securit.

Instrument transformers used for network control supply important information for determining the state of the operating conditions of the network.

Instrument transformers technology can also empower the grid with auxiliary power supply and highly precise power quality measurements.

Definition, Types And Connection

Instrument transformers are current and voltage transformation devices that are used to step down the transmission and distribution line voltages and currents to levels that can safely operate measuring instruments, protection devices and control relays by isolating it from the supply voltages.

Current transformers serve two purposes: 1) facilitates the measurement of high currents and 2) Insulation of meters, instruments and protection relays from high voltages.

The secondary circuit of connected of the current transformer must never be opened while the transformer is excited by primary current, because due to higher turns ratio, high voltages are induced at the secondary which may be hazardous to insulation and to personnel and because the accuracy of the transformer may be adversely affected.

Capacitive-coupled type: A capacitive-coupled voltage transformer is a combination of capacitance voltage divider and electromagnetic type PT. Optical type: An optical voltage transformer works on the principle of Kerr effect, by which the light which is reflected from a magnetized surface may change both polarization and reflected intensity.

Comparison of current transformer and potential transformer Burden and accuracy in instrument transformers.

Advantages of instrument transformers They isolate measuring instruments and control circuits from high voltage circuits.

Several instruments can be connected to a single instrument transformer provided the combined burden will not exceed the rated burden of the transformer.

Instrument Transformers

When used for protection purposes, the instrument transformer outputs must accurately represent the transmission line values during both steady-state and transient conditions.

These critical signals provide the basis for circuit-breaker operation under fault conditions, and as such are fundamental to network reliability and security.

Instrument transformers used for network control supply important information for determining the state of the operating conditions of the network.

Instrument transformers technology can also empower the grid with auxiliary power supply and highly precise power quality measurements.

Please browse our instrument transformers brochure here.

Instrument Transformer

Instrument transformers are high accuracy class electrical devices used to isolate or transform voltage or current levels.

The most common usage of instrument transformers is to operate instruments or metering from high voltage or high current circuits, safely isolating secondary control circuitry from the high voltages or currents.

The primary winding of the transformer is connected to the high voltage or high current circuit, and the meter or relay is connected to the secondary circuit.

Current transformers are a series-connected type of instrument transformer.

A current clamp uses a current transformer with a split core that can be easily wrapped around a conductor in a circuit.

This is a common method used in portable current measuring instruments but permanent installations use more economical types of the current transformer.

Care must be taken that the secondary winding of a CT is not disconnected from its low-impedance load while current flows in the primary, as this may produce a dangerously high voltage across the open secondary and could permanently affect the accuracy of the transformer.

Zydus Life

The new logo is a stylized visualization of two hearts with ‘us’ at the core.

Emphasizing that everything we do is about ‘Us’. An inclusive community of employees, patients, caregivers, partners, customers, investors and stakeholders.

The new ideology is a combines empathy and dynamism.

This is brought to life through a new visual identity that delivers our future ready brand transformation.

Positioning Zydus as a more path-breaking, inclusive, patient-centric, dynamic, global organization.

Cadila Healthcare Limited

Equipment ID #CH/PM/013 -(4) active ingredients were identified in swab and(4) residues out of(4) products processed in the equipment.

Equipment ID #CH/TS/013 -(4) active ingredients were identified in swab and(4) residues out of(4) products processed in the equipment.

Equipment ID #CH/MC/TAB/2004/176 -(4) active ingredients were identified in swab and(4) residues out of(4) products processed in the equipment.

In your response, you committed to corrective and preventive actions for non-dedicated equipment, including revisions to cleaning procedures, mechanical changes to equipment to prevent(4), cleaning validation for all processing equipment, and further testing to analyze reserve samples of batches manufactured using(4) to quantify the potential carryover of previous products.

This should include, but not be limited to: Identification of any inadequacies of cleaning procedures and practices for each piece of manufacturing equipment used to manufacture more than one product.

As part of the impact assessment, you evaluated the qualification reports for other products that utilize the same(4) and concluded that there was no impact on other(4) products.

A risk assessment of personnel and environmental monitoring data since April 2017, including but not limited to identification of adverse trends or acute findings, and any potential impact on marketed products.

Cadila Healthcare Share Price: Buy Cadila Healthcare, Target Price Rs 425: Yes Securities

Yes Securities has buy call on Cadila Healthcare with a target price of Rs 425.

The current market price of Cadila Healthcare Ltd. is Rs 400.75.

Time period given by analyst is Intra Day when Cadila Healthcare Ltd. price can reach defined target.

Cadila Healthcare Ltd., incorporated in the year 1995, is a Large Cap company operating in Pharmaceuticals sector.

Financials For the quarter ended 31-12-2021, the company reported a Consolidated Total Income of Rs 3715.80 Crore, down -3.19 % from last quarter Total Income of Rs 3838.10 Crore and down -2.81 % from last year same quarter Total Income of Rs 3823.10 Crore.

Company reported net profit after tax of Rs 488.30 Crore in latest quarter.

Promoter/FII Holdings Promoters held 74.88 per cent stake in the company as of 31-Dec-2021, while FIIs owned 3.79 per cent, DIIs 11.81 per cent.

Company, Directors And Contact Details

It is classified as Non-govt company and is registered at Registrar of Companies, Ahmedabad. Its authorized share capital is Rs. 1,724,999,940 and its paid up capital is Rs. 1,023,742,590.

View Events Timeline – List of all company events since inception.

Immovable property or any interest therein; Book debts; Movable property.

Immovable property or any interest therein; Movable property.

If the company has changed line of business without intimating the Registrar or is a diversified business, classification may be different.

We are adding and updating information about hundreds of thousands of companies every day, and periodically add companies to the queue for being updated.

You can ask for a company to be added to the front of the queue for updating, especially useful if the address, directors, or other critical information has changed.

Zydus: Cadila Healthcare Renamed Zydus Lifesciences, Health News, ET HealthWorld

…. Ahmedabad: The Zydus group announced its new brand identity with the listed entity of the group Cadila Healthcare Ltd to be known as Zydus Lifesciences Ltd. The company’s new brand identity brings together two hearts in purple and teal colours symbolising its commitment to science and innovation along with care and nurturance.

Heralding a bold new vision for the organisation, Pankaj R Patel, Chairman, Zydus Lifesciences Ltd, said, “With differentiated approaches, we have been addressing healthcare challenges globally, creating healthier communities. Reaffirming this commitment, we will continue to unlock new possibilities that can impact lives and empower people with life-changing discoveries.”

Sharing his insights on the new identity, Dr Sharvil Patel, Managing Director, Zydus Lifesciences Ltd, said, “Our new brand identity is a confluence of what we truly are. A global lifesciences company driven by the purpose of delivering care and nurturance for the patients, backed by the power of innovation, science and cutting edge technology.”

With this new identity, the company has reaffirmed its vision, mission and purpose, aligning itself to science, innovation and health.

Follow and connect with us on Twitter, Facebook, Linkedin, Youtube.

Flow-Through Shares

Certain corporations in the mining, oil and gas, and renewable energy and energy conservation sectors may issue FTSs to help finance their exploration and project development activities.

Junior resource corporations often have difficulty raising capital to finance their exploration and development activities.

Many are in a non-taxable position and do not need to deduct their resource expenses.

The FTS mechanism allows the issuer corporation to transfer the resource expenses to the investor.

A junior resource corporation, in particular, benefits greatly from FTS financing.

Deductions for resource expenses renounced by eligible corporations; and.

Investment tax credits for individuals on resource expenses in the mining sector that qualify as flow-through mining expenditures.

How Flow Through Shares Work

I’ve written several articles over the years on how flow through shares work, what they are, their associated advantages.

Overall, I think the most important takeaway when it comes to flow through shares is that they should really only be considered by people who are in high tax brackets and who really understand how risk and investing go together on an advanced level OR people who wish to donate in a very tax efficient manner.

Thoroughly understanding just how risky your flow through shares are, as well as your personal risk tolerance, are prerequisites for being successful in this field.

Another way to use flow through shares to your advantage is to make them work for you by maximizing your charitable donations.

Anyone can invest in flow through shares the corporation that issues the flow through shares must be a principal-business corporation.

I personally have dabbled in flow through shares, but have decided that long-term, the juice just isn’t worth the squeeze for me; consequently, I don’t currently possess any flow through shares in my portfolio.

Flow through shares can be purchased directly from companies offering them, through mutual fund firms, and even from your local financial advisor.

Flow-Through Shares

Executive Summary Flow-through shares are a financing tool available to a Canadian resource company that allows it to issue new equity to investors at a higher price than it would receive for “Normal” shares, thereby assisting it in raising money for exploration and development.

Essentially, the investors and the corporation agree that the investors will purchase flow-through shares from the corporation, the corporation will incur certain expenditures on CEE within a certain time period, and the corporation will renounce that CEE in favour of the investors.

The basic principle behind flow-through shares, which are unique to the resource sector in Canada, is that a mining corporation willing to forego the tax benefit of certain CEE and CDE amounts that it incurs can “Renounce” these expenditures to investors buying shares in the corporation in certain circumstances.

The corporation benefits because it can issue the shares to the shareholders for a higher price than they would otherwise be willing to pay, due to the tax benefit associated with being able to deduct the CEE or CDE. The investors benefit by being able to reduce their incomes for tax purposes by virtue of claiming deductions for the renounced CEE and CDE. While the corporation loses the ability to deduct the CEE or CDE renounced to the FTS investors, the net present value of those deductions may be quite small if the corporation is unlikely to have enough taxable income to utilize these deductions in the near future.

The agreement will provide that the PBC must incur qualifying expenditures at least equal to the amount to be paid for the shares within a set time period, and renounce them in favour of the FTS investors by no later than a certain date.

Table 1 sets out a simple example illustrating the consequences to a FTS investor who purchases 10,000 FTS of a mining company at a $1/share premium over the trading price of the “Ordinary” common shares of the company, and later sells them into the market at the prevailing trading price.

TABLE 1: FTS CASH-FLOW EXAMPLE Assumptions Flow-through shares purchased 10,000 Price per FTS $10 Mining company regular common share trading price $9 FTS premium per share $1 Investor’s federal /provincial tax rate 46% CEE renounced per FTS $10. Investor Cash Out Investor Cash In Cost of FTS $100,000 Tax savings from $100,000 renounced CEE $ 46,000 Investor’s proceeds from selling FTS in market $ 90,000 Tax owing on capital gain from sale of FTS $ 20,700.

Flow-Through Share

A flow-through share is a tax-based financing incentive that is available to, among others, the mining sector.

A FTS is a type of share issued by a corporation to a taxpayer, pursuant to an agreement with the corporation under which the issuing corporation agrees to incur eligible exploration expenses in an amount up to the consideration paid by the taxpayer for the shares.

The corporation “Renounces” to the taxpayer an amount in respect of the expenditures so that the exploration and development expenses are considered to be the taxpayer’s expenses for tax purposes.

As a result of the corporation renouncing the expenses, the shareholder can deduct the expenses as if incurred directly.

The FTSs must be newly issued shares that have the attributes generally attached to common shares.

The flow through donation financing structure helps senior Canadian philanthropists significantly reduce the after-tax cost of their charitable gifts while ensuring the charity chosen by the donor receives the full pledge amount immediately on closing and net of all fees and expenses.

The process is involves the simultaneous subscription to flow through shares, thus accessing the Canadian Exploration Expense and associated investment tax credit benefits, donation of the shares to the charity of the donors choice, and the sale by the charity of the shares to institutional investors which enables the original donor to receive a donation tax receipt.

Flow-Through Shares

Flow-through shares are stocks that can only be purchased directly from Canadian oil and mineral exploration companies, usually at a slight premium.

Flow-through shares are beneficial mainly to people in a high income tax bracket.

You need to be aware that the cost base of the shares is reduced by the deduction you have claimed.

Once you purchase the flow-through shares and have taken the CEE deduction, you are relying on the company to spend the money correctly.

It is common that the flow-through shares acquired may not be traded for an extended period, generally for 24 months, and you are subject to market risks related to the value of the shares.

In order for you to, at a minimum, break-even on the transaction, the market value of the shares when you sell them cannot be less than 63.45% of the original purchase price.

Purchasing flow-through shares can be very beneficial but, like any other venture into the stock market, does not come without risks.

Flow-Through Shares

THE MINERAL EXPLORATION TAX CREDIT. In addition to regular flow-through shares that provide 100% deduction for exploration, the federal METC is a 15% non-refundable tax credit applicable only to grassroots exploration in Canada, and deductible from federal income taxes payable.

Plus provincial and territorial deductions and tax credits.

PROVINCIAL TAX INCENTIVES. On top of the federal incentives, a number of provinces provide an additional incentive that further reduces net cost to the investor.

Additional tax credits that apply to the provincial portion of income tax.

Quebec allows investors to deduct up to 120% of the cost of certain qualifying exploration expenses incurred by non-producing companies.

The provincial deduction and tax credits apply only to expenditures in applicable provinces and are only available to taxpayers residing within, or otherwise taxable in, the jurisdiction where the exploration is taking place.

The effect of these incentives varies depending on the jurisdiction.

The higher the income tax bracket of the investor the higher the tax benefits of investing in flow-through shares would be.

If you purchase flow-through shares of qualifying companies, you can deduct up to 100% of the cost of the shares from your personal income.

If you purchased the share for $1 and sold it for $1, you would have a capital gain of $1. Due to the fact that you will have an income tax deduction of $1 as a result of the purchase of the flow-through share, and because only 50% of capital gains is included in your taxable income you would still have a net after-tax benefit from purchasing Flow-through shares.

Upon receipt of the shares, the charity immediately sells the shares to pre-arranged institutional investors and the donor receives a charitable donation tax receipt for the full value of the shares donated equal to the net intended gift plus the closing costs.

The format enables the donor to also simultaneously sell some of the shares to the same end buyer that will purchase the shares from the charity at the same price that the shares are sold by the charity according to a deal pre-arranged by the FTSD provider.

As a result of income tax changes that were implemented in 2012, capital gains tax is payable on donation of flow-through shares to charities.

FTSD structures use tax incentives available to all Canadians but the market risk normally associated with a flow-through share purchase is mitigated by arranging for the immediate sale of the shares, on date of issuance, to an end buyer, at an agreed price, negotiated at arm’s length by the FTSD provider.

Random-Access Memory

The two main types of volatile random-access semiconductor memory are static random-access memory and dynamic random-access memory.

Magnetic core memory was the standard form of computer memory system until displaced by solid-state MOS semiconductor memory in integrated circuits during the early 1970s.

Prior to the development of integrated read-only memory circuits, permanent random-access memory was often constructed using diode matrices driven by address decoders, or specially wound core rope memory planes.

MOS memory overtook magnetic core memory as the dominant memory technology in the early 1970s.

Dynamic random-access memory allowed replacement of a 4 or 6-transistor latch circuit by a single transistor for each memory bit, greatly increasing memory density at the cost of volatility.

This entire pool of memory may be referred to as “RAM” by many developers, even though the various subsystems can have very different access times, violating the original concept behind the random access term in RAM. Even within a hierarchy level such as DRAM, the specific row, column, bank, rank, channel, or interleave organization of the components make the access time variable, although not to the extent that access time to rotating storage media or a tape is variable.

First of all, as chip geometries shrink and clock frequencies rise, the transistor leakage current increases, leading to excess power consumption and heat… Secondly, the advantages of higher clock speeds are in part negated by memory latency, since memory access times have not been able to keep pace with increasing clock frequencies.

The human brain has memory, and it is the most essential part played by the brain, memory helps in remembering things, people remember their past due to the memory present in the brain computers have memory too.

In human brains, there are different ways of keeping a memory, like short-term memory, long-term memory, implicit memory, etc.

In computers, there are different types of memories or different ways of saving memories.

Cache memory is helpful in speeding up the CPU as it is a high-speed memory, It consumes less time but is very expensive.

RAM is a volatile memory, which means, it is present as long as the Computer is in ON state, as soon as the computer turns OFF, the memory is erased.

RAM is the fastest memory it is an internal memory for the computer.

SRAM is costlierSRAM has a lower densityThe power consumption of SRAM is less but when it is operated at higher frequencies, the power consumption of SRAM is compatible with DRAM.DRAM. DRAM is used for the Main memory, it has a different construction than SRAM, it used one transistor and one capacitor, it is needed to get recharge in milliseconds due to the presence of capacitor.

Random Access Memory

kB of RAM. In general, it is possible to extend the memory by adding external memory chips.

Data is written to the memory when the CE and the WE signals are active low, and data is read from the memory when the CE and the OE signals are active low.

The broadest classification is random access memory.

RAM is called random access memory because any data word is accessed with the same delay as any other.

Enhanced Dynamic Random Access Memory actually integrates SRAM within the DRAM, and is usually used as level 2 cache.

Is the most important type of memory in semiconductors because of high-speed access to a memory word at any address.

Memory cell for dynamic RAM.Every four or four and a half years, RAM with memory capacity four times greater than the previous one has been introduced with a new processing technology.

Random Access Memory

RAM is the internal memory of the CPU for storing data, program, and program result.

Access time in RAM is independent of the address, that is, each storage location inside the memory is as easy to reach as other locations and takes the same amount of time.

Data in the RAM can be accessed randomly but it is very expensive.

RAM is volatile, i.e. data stored in it is lost when we switch off the computer or if there is a power failure.

Static RAM. Dynamic RAM. Static RAM. The word static indicates that the memory retains its contents as long as power is being supplied.

SRAM is thus used as cache memory and has very fast access.

Dynamic RAM. DRAM, unlike SRAM, must be continually refreshed in order to maintain the data.

What Is RAM & What’S It Do?

Now that you know what RAM is and what it stands for, you’ll have a much better idea of how RAM works to help your computer streamline your work.

RAM stores the data that helps your computer perform its most important tasks, such as loading apps, browsing websites, and editing documents.

RAM lets you open apps and files quickly, because your computer can easily find the data in its short-term memory.

Another type of RAM is SDRAM, which is a subset of DRAM. SDRAM connects RAM to the computer’s system clock.

If you browse the web and edit basic documents like Word and Excel files, most computers will perform very well with 8 GB of RAM. You can easily check your RAM memory on your desktop or laptop computer, and it probably has between 4 and 8 GB – unless it’s really old.

While RAM is a computer’s short-term memory, ROM is the unique set of instructions a computer needs to turn on.

That’s why it’s essential to have enough RAM. How to speed up your devices without upgrading RAM. If your computer doesn’t have enough space to do what you need, the first solution is simple and much cheaper than buying more RAM – simply clear up more space.

Definition From SearchStorage

If RAM fills up, the computer’s processor must repeatedly go to the hard disk to overlay the old data in RAM with new data.

Having more RAM in a computer cuts down on the number of times the processor must read data from the hard disk, an operation that takes longer than reading data from RAM. RAM access time is in nanoseconds, while storage memory access time is in milliseconds.

Static RAM requires several transistors to retain one bit of data compared to dynamic RAM which needs only one transistor per bit.

History of RAM: RAM vs. SDRAM. RAM was originally asynchronous because the RAM microchips had a different clock speed than the computer’s processor.

With virtual memory, data is temporarily transferred from RAM to disk storage, and virtual address space is increased using active memory in RAM and inactive memory in an HDD to form contiguous addresses that hold an application and its data.

Using virtual memory, a system can load larger programs or multiple programs running at the same time, letting each operate as if it has infinite memory without having to add more RAM. Virtual memory is able to handle twice as many addresses as RAM. A program’s instructions and data are initially stored at virtual addresses, and once the program is executed, those addresses are turned into actual memory addresses.

With physical memory alone, programs work directly from RAM. RAM vs. flash memory.

What Does Computer Memory Do?

Not sure exactly what computer memory is for or how it works? We cover all the bases, from what RAM is to how it works and why it is worth getting an upgrade.

Computer random access memory is one of the most important components in determining your system’s performance.

There are ways to see if your computer needs more memory, and to make sure you are buying memory that is compatible with the other components in your system.

To prevent users from inserting incompatible memory, modules are physically different for each memory technology generation.

One of the reasons for industry-wide standardization in memory is that computer makers need to know the electrical parameters and physical shape of the memory that can be installed in their computers.

When you turn on your computer and open a spreadsheet to edit it, but first check your email, you’ll have used memory in several different ways.

Memory is almost always being actively used by your computer.

What Is Random Access?

Random access refers to the ability to access data at random.

In a random-access system, you can jump directly to point Z. Disks are random access media, whereas tapes are sequential access media.

The terms random access and sequential access are often used to describe data files.

A random-access data file enables you to read or writeinformation anywhere in the file.

In a sequential-access file, you can only read and write information sequentially, starting from the beginning of the file.

If you are always accessing information in the same order, a sequential-access file is faster.

If you tend to access information randomly, random access is better.

Random Access

Random access is the ability to access an arbitrary element of a sequence in equal time or any datum from a population of addressable elements roughly as easily and efficiently as any other, no matter how many elements may be in the set.

In computer science it is typically contrasted to sequential access which requires data to be retrieved in the order it was stored.

Given all the coordinates, a program can access each record about as quickly and easily as any other.

The operative attribute is that the device can access any required record immediately on demand.

The opposite is sequential access, where a remote element takes longer time to access.

A more modern example is a cassette tape and a CD. In data structures, direct access implies the ability to access any entry in a list in constant time.

Self-balancing binary search trees may provide an acceptable compromise, where access time is not equal for all members of a collection, but the maximum time to retrieve a given member grows only logarithmically with its size.

The algorithm required to solve a problem on a sequential computer is called a sequential algorithm.

Algorithms written to solve a problem on a parallel computer are called parallel algorithms.

The sequential algorithm is written in the form of steps, which are done sequentially by PE, i.e. sequential algorithm uses sequential steps to solve a problem.

In a parallel algorithm, we have to see where the communication is taking place, where we have to move the output of particular steps.

Algorithms written for a particular architecture cannot be applied to another architecture, in other words, to solve the same problem on different parallel computers, different algorithms must be written based on parallel computer architecture.

Each step, READ, COMPUTE, WRITE, is assumed to take O(1) time in the case of RAM. It should be noted that not all processors need to perform a given step of the algorithm.

Algorithms for PRAM have to specify which subset of processors should be active during the execution of a phase.

Definition From Techopedia

In computer science, random access is the capability to have access to any item from a given population of elements at random.

Random access is the opposite of sequential access, as sequential access locates elements by beginning at a particular predefined location and then traversing through all of the information in order to find the given item.

Apart from arrays there are only a few data structures which are capable of supporting random access.

Random access is also used in algorithms such as integer sorting and binary search.

One of the unique features of random access is that any required record can be accessed immediately on demand and access time is similar for a remote element as it would be for a nearby element.

In many electronic devices, accessing data sequentially works faster than accessing the data at random, mostly due to the manner in which the disk hardware has been designed.

The seek operation, in most cases, takes a larger number in case of random access compared to sequential access.

Random Access Response

As long as the devices that performed random access in the same resource used different preambles, no collision will occur and from the downlink signaling it is clear to which device(s) the information is related.

The device already has a unique identity allocated in the form of a C-RNTI.In the case of downlink beamforming, the random-access response should follow the beamforming used for the SS block, which was acquired during the initial cell search.

Unlike in idle mode, message 3 does not include an RRC message, and because the device has already been assigned with a C-RNTI, which the device includes in message 3, the contention resolution in the fourth step is in this case performed using C-RNTI rather than TC-RNTI.The base station can also order a device in CE mode A or B to initiate a random access procedure by sending a so-called MPDCCH order to the device.

1 Random access procedureThe rapid growth of the number of MTC devices complicates considerably their support in LTE-Advanced Networks and may significantly increase the probability of congestion and access failure when performing the random access procedure.

To attach or connect to the network, every MTC device should first accomplish the random access procedure.

M2M devices usually perform such access in a contention manner.

Step 1: Random access preamble transmission: in the first message, the MTC device chooses randomly a sequence code called a preamble, among the set of available preambles.

Random Access Memory

RAM is the internal memory of the CPU for storing data, program, and program result.

Access time in RAM is independent of the address, that is, each storage location inside the memory is as easy to reach as other locations and takes the same amount of time.

Data in the RAM can be accessed randomly but it is very expensive.

RAM is volatile, i.e. data stored in it is lost when we switch off the computer or if there is a power failure.

Static RAM. Dynamic RAM. Static RAM. The word static indicates that the memory retains its contents as long as power is being supplied.

SRAM is thus used as cache memory and has very fast access.

Dynamic RAM. DRAM, unlike SRAM, must be continually refreshed in order to maintain the data.

ALOHA, CSMA, CSMA/CA And CSMA/CD

The ALOHA protocol or also known as the ALOHA method is a simple communication scheme in which every transmitting station or source in a network will send the data whenever a frame is available for transmission.

Stations can transmit the data randomly i.e. any number of stations can transmit data at any time.

Till now we have understood that when 2 or more stations start sending data, then a collision occurs, so this CSMA method was developed to decrease the chances of collisions when 2 or more stations start sending their signals over the data link layer.

How do they do it? The CSMA makes each station to first check the medium before sending any data packet.

1-persistent mode: In this, first the node checks the channel, if the channel is idle then the node or station transmits data, otherwise it keeps on waiting and whenever the channel is idle, the stations transmit the data-frame.

Non-persistent mode: In this, the station checks the channel similarly as 1-persistent mode, but the only difference is that when the channel is busy it checks it again after a random amount of time, unlike the 1-persistent where the stations keep on checking continuously.

P-persistent mode: In this, the station checks the channel and if found idle then it transmits the data frame with the probability of P and if the data is not transmitted then the station waits for a random amount of time and again transmits the data with the probability P and this cycle goes on continuously until the data-frame is successfully sent.

Ferroelectric RAM

FeRAM is one of a growing number of alternative non-volatile random-access memory technologies that offer the same functionality as flash memory.

FeRAMs have data retention times of more than 10 years at +85 °C. Market disadvantages of FeRAM are much lower storage densities than flash devices, storage capacity limitations and higher cost.

In the fall of 2005, Ramtron reported that they were evaluating prototype samples of an 8-megabit FeRAM manufactured using Texas Instruments’ FeRAM process.

In a DRAM cell capacitor, a linear dielectric is used, whereas in a FeRAM cell capacitor the dielectric structure includes ferroelectric material, typically lead zirconate titanate.

In the figure a “1” is encoded using the negative remnant polarization “-Pr”, and a “0” is encoded using the positive remnant polarization “+Pr”. In terms of operation, FeRAM is similar to DRAM. Writing is accomplished by applying a field across the ferroelectric layer by charging the plates on either side of it, forcing the atoms inside into the “Up” or “Down” orientation, thereby storing a “1” or “0”.

In contrast, FeRAM only requires power when actually reading or writing a cell.

As a consequence, the areal bit densities of flash memory are much higher than those of FeRAM, and thus the cost per bit of flash memory is orders of magnitude lower than that of FeRAM. The density of FeRAM arrays might be increased by improvements in FeRAM foundry process technology and cell structures, such as the development of vertical capacitor structures to reduce the area of the cell footprint.

What Is FRAM Memory: Ferroelectric RAM » Electronics Notes

FRAM, ferroelectric RAM is a form of random access memory that combines speed & non-volatility.

FRAM, ferroelectric RAM, is a form of random access memory that combines the fast read and write access of dynamic RAM, DRAM whilst also providing non-volatile capability.

Ferroelectric RAM is also known as F-RAM or FeRAM, as and it is able to compete with Flash technology in many areas, although there are several advantages and disadvantages to using it.

While the name FRAM or ferroelectric RAM seems to indicate that an iron element exists within the memory this is not actually the case.

Currently ferroelectric RAM is not as widely used as many of the more established technologies including DRAM and Flash.

FRAM technology is now being embedded into chips using CMOS technology to enable MCUs to have their own FRAM memories.

FRAM is able to offer many advantages and can be used in many areas, but as in many cases, the use of FRAM memory is a balance of a number of characteristics and parameters which need to be made for any particular circuit design.

Introduction To FRAM Including Its History

FRAM is one of the alternative non-volatile random-access memory technologies that provide the same functions as flash memory.

Although the name FRAM or ferroelectric RAM seems to indicate the presence of iron in the memory, it is not.

After the introduction of metal-oxide-semiconductor dynamic random-access memory chips in the early 1970s, the development of FRAM began in the late 1980s.

In 2001, Texas Instruments cooperated with Ramtron to develop FRAM test chips with an improved 130 nm process.

As a result, the area density of flash memory is much higher than that of FRAM, so the cost per bit of flash memory is several orders of magnitude lower than that of FRAM. In 2005, Ramtron reported a large number of sales of its FeRAM products in various fields, including electricity meters, automotive, business machines, and instrumentation, medical equipment, industrial microcontrollers, and radio frequency identification tags.

Texas Instruments has integrated a certain amount of FRAM memory in its new FRAM series of MSP430 microcontrollers.

FRAM can provide many advantages and can be used in many fields, but in many cases, the use of FRAM memory is a balance between many characteristics and parameters, and these characteristics and parameters need to be designed for any specific circuit design.

Studymafia.org ABSTRACT Ferroelectric memory is a new type of semiconductor memory, which exhibit short programming time, low power consumption and nonvolatile memory, making highly suitable for application like contact less smart card, digital cameras which demands many memory write operations.

A ferroelectric memory cell has at least one ferroelectric capacitor to store the binary data, and one transistor that provide access to the capacitor or amplify its content for a read operation.

Studymafia.org FERROELECTRIC MEMORY ARCHITECTURE Ferroelectric memories have borrowed many circuit techniques from DRAM’s due to similarities of their cells and DRAM’s mature architecture.

Unlike the previous architecture, only a single memory cell can be selected by a simultaneous activation of a WL and a PL. This is the memory cell that is located at the Intersection of the WL and the PL. It is possible to select more than one memory cell in a row by activating their corresponding platelines.

Circuit Diagram of a pair of Ferroelectric Memory Cells for a Merged-line architecture Compared to a WL//PL architecture, the ML architecture enjoys a shorter read access time, as the PL capacitance is-now divided equally between two merged lines.

COMPARISON The memory cell of FRAM is configured with one transistor and one capacitor is DRAM. It can also hold data even when the power is switched off as can flash memory, which is a representative nonvolatile memory device.

Ferroelectric memories, on the other hand, are superior to EPROM’s and Flash memories in terms of write-access time and overall power consumption, and hence, target applications where a nonvolatile memory is required with such features.

Ferroelectric RAM

It is not always easy to do this reliably, so I went looking for alternatives and discovered Ferroelectric RAM. FRAM is a non-volatile memory technology that relies on the special properties of ferroelectric materials.

Unlike linear dielectric materials, ferroelectric materials can exhibit a remnant electrical polarization after an electrical field is removed.

Like DRAM, read operations are destructive and internal circuitry has to write the value back into the cell when it is read. The read/write endurance of FRAM is guaranteed at 100 trillion cycles and data retention typically greater than 100 years at 65°C. So, what’s the downside? Cost of course.

At the time of writing, a typical 16KB FRAM, such as the Cypress FM24CL16B, costs $1.68 in unit quantity, while a comparable EEPROM, the ON Semiconductor CAT24C16WI costs just $0.16.

FRAM seems to be about 10 times the cost of an equivalent EEPROM across the board.

I’m not building a high-volume product, so I will use the FRAM this time because the additional cost is worth way less than the design effort needed to be sure an EEPROM solution will work every time.

Rew has maintained a hands-on interest in electronics, particularly embedded systems, power electronics, and control theory in his free time.

What Is Ferroelectric RAM?

It differs from the common RAM used in most personal computers in that it is non-volatile, meaning that it retains the data stored in it when power is turned off to the device, not true of standard dynamic RAM. The unique properties of the material of which the FRAM is made gives it a natural ferroelectric state, which means that it has a built-in polarization that lends itself to the semi-permanent storage of data without a need for power.

The main disadvantages of FRAM are that the storage density for data is considerably less than that of other types of RAM and it is more difficult to produce, as the ferroelectric layer can be easily degraded during silicon chip manufacturing.

Since ferroelectic RAM cannot hold a great amount of data and would be expensive to make for applications that require a lot of memory, it is most often used in portable computer-based devices like smart cards tied to security systems to enter buildings and radio frequency identifier tags used on consumer products to track inventory.

The material most often used to manufacture ferroelectric RAM as of 2011 is lead zirconate titanate, though the history of the technology can be traced back to its conception in 1952 and first production near the end of the 1980s.

While the architecture is based on the same model as DRAM and both store data as binary strings of ones and zeros, only ferroelectric RAM has phase-change memory, where the data is permanently embedded until an applied electric field erases or overwrites it.

In this sense, ferroelectric RAM functions in the same way as flash memory or an EEPROM chip, except that the read-write speed is much faster and can be repeated more times before the FRAM chip begins to fail, and the power consumption level is much lower.

Since ferroelectric RAM can have read-write access rates 30,000 times faster than a standard EEPROM chip, along with the fact that it can last 100,000 times longer and have only 1/200th of the power consumption of EEPROM, it is a type of precursor to racetrack memory.

Ferroelectric Random Access Memory Technique

Volatile memory includes static random access memory and dynamic random access memory.

Ferroelectric memory is compatible with all the functions of RAM, and it is a non-volatile memory like a ROM. In other words, ferroelectric memory bridges the gap between these two types of storage, a type of non-volatile RAM. Compared with traditional non-volatile memory, it has attracted much attention due to its advantages such as low power consumption, fast read and write speed, and strong anti-irradiation capability.

Ferroelectric memory, also known as F-RAM or FeRAM, is a type of random access memory with fast read and write speed, and the ability to retain data after power is turned off is combined, which is the most commonly used type of personal computer memory.

Since it is not as dense as dynamic random access memory and static random access memory, that is, it cannot store as much data as they do in the same space.

Because there is no atomic collision in the entire physical process, the ferroelectric memory has the characteristics of high read and write speed, ultra-low power consumption, and unlimited writes, making it very suitable to act as temporary storage memory in important systems to transfer various data between subsystems, for each subsystem to read and write frequently.

This design greatly improves the efficiency of ferroelectric memory and reduces the production cost of ferroelectric memory products.

Ferroelectric memory is an emerging non-volatile memory.

Ceva Santé Animale

Ceva Santé Animale is a multinational animal health company based in Libourne, France.

Established in 1999, Ceva undertakes research, development, production and marketing of pharmaceutical products and vaccines, and also provides complementary services and equipment, for companion animals, poultry, ruminants and swine.

With revenues of US$1.16 billion for 2017, Ceva is the 6th largest animal health company in the world and the biggest French multinational in the sector based on revenue.

2017: Joint-venture agreement between EBVAC, China and Ceva to create a new business, Ceva Ebvac, focused on the swine vaccine sector.

In 2016, Ceva won the best company in Europe category in Animal Pharm’s annual industry awards.

Wageningen Bioveterinary Research and Ceva are developing veterinary vaccines for the control ofemerging infectious animal diseases, such as Rift Valley fever and Influenza.

According to an investigation published in French journal Libération, CEVA bought the eCG in Syntex bloodfarms, accused of cruelty to animals by NGOs Eyes on Animals, Tierschutzbund Zurich, Animal Welfare Foundation and Welfarm, among others.

MicroStrategy provides the answer In 2009, CEVA received proofs of concept from MicroStrategy, Cognos and Business Objects.

CEVA’s Chief provide a great technology, they Information Officer, Francois Tricot says, “Our sales reps only have a short 15 are a great team that we minutes with their clients and they need to use all this time for their visit; they can’t consider a partner, not just a waste time waiting for technology or information. The MicroStrategy sales app is supplier.” very easy to use and provides quick access to all the data they need to customize a conversation with a client, even if they don’t have network connectivity.

Sales reps MicroStrategy was not only our don’t like having to go back at the end of the day and update the CRM tool; they choice because of their want a tool that helps them perform their job throughout the day.

” – Francis Tricot, Chief Information Officer, CEVA Santé Animale When discussing CEVA’s implementation experience, Tricot says, “MicroStrategy’s consultant team worked very quickly to make our app project a success. 12:30 PM iPad 100% MicroStrategy does not just provide a great technology, they are a great team that we consider a partner, not just a supplier.” It was a real diamond for CEVA to discover that not only was MicroStrategy their BI solution but that MicroStrategy also provides the platform for building Mobile Applications.

” CEVA’s iPad application uses the MicroStrategy map widget so that sales representatives can schedule their day, see nearby customers, and can quickly make changes when cancellations occur.

MicroStrategy provides a return on investment A timely return on an investment is important when choosing the tools -Joshua Pickell Territory Manager, DC and VA necessary for a company’s growth.

CEVA is seeing a great return on their investment by choosing MicroStrategy.

| Corporate Website PJSC “Nizhnekamskneftekhim”

On December 24, an extraordinary meeting of shareholders of PJSC Nizhnekamskneftekhim was held.

The renewed Board of Directors was elected by the shareholders.

Directorate of Synthetic Rubbers OOO SIBUR. At the meeting of the Board of Directors on December 27, Mikhail Karisalov was elected Chairman of the Board of Directors of PJSC Nizhnekamskneftekhim, Airat Safin – Deputy Chairman of the Board of Directors of PJSC Nizhnekamskneftekhim.

Nizhnekamskneftekhim PAO NKNC 9.75 07-Dec-2028

Disclaimer: Fusion Media avvisa che i dati contenuti in questa pagina non sono necessariamente in tempo reale.

Tutti i prezzi relativi a CFD, criptovalute e Forex non sono forniti dalle borse ma dai market mover, quindi i prezzi possono non essere del tutto accurati e possono differire dagli attuali prezzi di mercato.

Pertanto, i prezzi sono da considerarsi solo indicativi e non adatti per fini di trading.

Fusion Media, dunque, non assume alcuna responsabilità per eventuali perdite di capitale causate dall’uso di questi dati.

Fusion Media o chiunque sia coinvolto con Fusion Media non accetta alcuna responsabilità per perdite o danni risultanti dall’uso delle informazioni quali quotazioni, grafici, segnali di buy/sell presenti nel sito.

Si prega di informarsi correttamente circa i rischi e i costi associati al trading relativo ai mercati finanziari, uno degli investimenti considerati a maggior rischio.

La versione inglese di questa convenzione da considerarsi quella ufficiale e preponderante nel caso di eventuali discrepanze rispetto a quella redatta in italiano.

Nizhnekamskneftekhim Increases Revenue And Profit In First Half Of Year

According to published data, the revenue of Nizhnekamskneftekhim PJSC in the first half of 2021 reached 118,2 billion rubles, which is 51,1bn more than during the analogous period in 2020.

Gross profit was over 38 billion rubles, which is above the number in the first half of 2020.

Sales revenue rose to 29,1 billion rubles against 9,4 billion in 2020.

Net profit from January to June amounted to 24,9 billion rubles against 2,9 billion rubles in the first half of 2020.

54,9 billion rubles of revenue were earned from January to March 2021, which is above last year’s level by 16,8 billion rubles.

In general revenue of Nizhnekamskneftekhim PJSC by Russian Accounting Standards in the first half of 2021 augmented 1,8 times compared to last year’s analogous period, to 118,2 billion rubles.

“The reason for such significant growth of indicators is obvious. If the first half of the last year was noted for a fall in demand and prices for both synthetic rubbers and plastics, prices skyrocketed in the first half of 2021. Plastics and rubbers approximately doubled over this time. Amid stable production output, manufacturers’ revenue notably increased,” says Alexey Kalachev, an analyst of FINAM FG. In 2021, Nizhnekamskneftekhim PJSC started to produce a new type of products – solution butadiene-styrene rubber with a capacity of 60,000 a year and styrene-butadiene-styrene thermoplastic elastomer.

Nizhnekamskneftekhim Holds Positions In The Polymer Market

Despite the difficult situation, the petrochemical flagship of Tatarstan – Nizhnekamskneftekhim PJSC, which is part of TAIF GC – keeps implementing investment projects designed for the next years by strengthening its positions in the Russian market of large-tonnage polymers.

The production line made by Nizhnekamskneftekhim includes different grades of polypropylenes, polyethylenes, ABS plastics, polystyrenes – tens of grades that can satisfy the most sophisticated demand of recyclers.

During the construction of plastic plants in 2000, Nizhnekamskneftekhim already aimed at import substitution that would allow filling the Russian market with high-quality products and driving out imported general-purpose PS, PP and PE grades.

ABS plastic is another product that recommended itself well in the polymer market.

“We used to have problems with plastic supplies. There were troubles when we worked with foreign companies, including from Korea. When Nizhnekamskneftekhim appeared in the market, the problems with ABS plastic supplies disappeared. Their plastic meets all international standards in terms of shininess, fluidity, frost tolerance, which is very important for us. This type of plastic met all standards here. We are very glad there is such an enterprise that addresses all problems, creates technical support,” Aleksandr Skromnov, head of Maintenance Supply and Procurement at POZIS JSC, told Realnoe Vremya.

A new player appeared in the polymer and LPE market in 2019 – ZapSibNeftekhim of SIBUR PJSC. Today this enterprise is the largest Russian manufacturer of a wide range of plastics.

Tobolsk-Polymer became first in PP production, Nizhnekamskneftekhim and Poliom are second, another big player in the PP market is ZapSibNeftekhim, which is followed by Tomskneftekhim and Neftekhimia.

Buy Hypodermic Needles Online

HealthWarehouse.com has been accredited by the National Association of Boards of Pharmacy® for Digital Pharmacy and is licensed / accredited with all 50 State Boards of Pharmacy.

Based in Florence, Kentucky, Healthwarehouse.com is the leader in Digital Pharmacy and a pioneer in affordable healthcare, providing incredible patient services since 2007.

Hypodermic Needle

A hypodermic needle is used for rapid delivery of liquids, or when the injected substance cannot be ingested, either because it would not be absorbed, or because it would harm the liver.

The hypodermic needle reduces contamination for two reasons: First, its surface is extremely smooth, which prevents airborne pathogens from becoming trapped between irregularities on the needle’s surface, which would subsequently be transferred into the media as contaminants; second, the needle’s surface is extremely sharp, which significantly reduces the diameter of the hole remaining after puncturing the membrane and consequently prevents microbes larger than this hole from contaminating the substrate.

Dr. Wood can be largely credited with the popularization and acceptance of injection as a medical technique, as well as the widespread use and acceptance of the hypodermic needle.

The basic technology of the hypodermic needle has stayed largely unchanged since the 19th century, but as the years progressed and medical and chemical knowledge improved, small refinements have been made to increase safety and efficacy, with needles being designed and tailored for very particular uses.

Development of the fully disposable hypodermic needle was spurred on in the 1950s for several reasons.

The end of the needle is bevelled to create a sharp pointed tip, letting the needle easily penetrate the skin.

The main system for measuring the diameter of a hypodermic needle is the Birmingham gauge; the French gauge is used mainly for catheters.

Medical Design And Outsourcing

Is a hollow needle commonly used with a syringe to inject substances into the body or extract fluids from it.

Large-bore hypodermic intervention is especially useful in treating catastrophic blood loss or shock.

A hypodermic needle also provides for rapid delivery of liquids.

Hypodermic needles also serve important roles in research requiring sterile conditions.

The hypodermic needle significantly reduces contamination during inoculation of a sterile substrate in two ways.

First, its surface is extremely smooth, preventing airborne pathogens from becoming trapped between irregularities on the needle’s surface, which could subsequently be transferred into the media as contaminants.

Second, the needle’s point is extremely sharp, significantly reducing the diameter of the hole remaining after puncturing the membrane, which consequently prevents microbes larger than the hole from contaminating the substrate.

What Is The Hypodermic Needle Theory? The Hypodermic Needle Theory In A Nutshell

The hypodermic needle theory was first proposed by communication theorist Harold Lasswell in his 1927 book Propaganda Technique in the World War.

The hypodermic needle theory is a communication model suggesting media messages are inserted into the brains of passive audiences.

In the intervening years between war, the ability for world leaders to influence their citizens using the media then became known as the hypodermic needle or “Magic bullet” theory.

Key takeaways: The hypodermic needle theory is a communication model suggesting media messages are inserted into the brains of passive audiences.

The hypodermic needle theory posits that a mass audience passively receives whatever message is being communicated by the media.

Harold Lasswell in his 1927 book Propaganda Technique in the World War explained how the hypodermic needle theory of communication suggests media messages are inserted into the brains of passive audiences.

While the hypodermic needle theory is still relevant today, it’s more relevant with centralized mass media like TV and radio, which message can be manufactured, controlled, and broadcasted to millions of people.

Affordable Houses & Apartments For Rent

As the largest source for affordable housing options online, our focus is to bring together Owners and Renters who are in search of the perfect affordable housing opportunities.

Our Market Rent Estimator tool offers free rent estimates for any rental property.

Find Affordable Rental Housing

May qualify for help from the U.S. Department of Housing and Urban Development to get affordable rental housing.

Find a HUD-approved housing counselor in your area online or call 1-800-569-4287 to find a local housing counseling agency Housing Counseling Agency: an organization with experts who provide advice on buying a home, renting, avoiding mortgage default and foreclosure, and credit issues.

There are three main types of affordable rental housing that are supported by HUD:.Privately owned, subsidized housing in which landlords are paid by the government to offer reduced rents to low-income tenants.

Public Housing provides affordable rental houses or apartments for low-income families, people who are elderly, and people with disabilities.

Housing Choice Voucher Program in which you find a rental property yourself, and use the voucher to pay for all or part of the rent.

Find out how the Housing Choice Voucher Program can help you pay for rental housing.

Housing discrimination happens when a housing provider gets in the way of a person renting or buying housing because of their.

Low Income Apartments In Indianapolis, Indiana

There are 312 low income housing apartment communities offering 23,793 affordable apartments for rent in Indianapolis, Indiana.

Indianapolis features 8,852 income based apartments.

Tenants of income based apartments typically pay no more than 30% of their income towards rent and utilities.

There are 14,813 rent subsidized apartments that do not provide direct rental assistance but remain affordable to low income households in Indianapolis.

Renters earning up to 30% of the Indianapolis AMI may qualify for rental assistance programs that target Extremely Low Income households.

Renters earning up to 50% of the Indianapolis AMI may qualify for rental assistance programs that target Very Low Income households.

Renters earning up to 80% of the Indianapolis AMI may qualify for rental assistance programs that target Low Income households.

Affordable Housing

Affordable housing is housing which is deemed affordable to those with a household income at or below the median as rated by the national government or a local government by a recognized housing affordability index.

In Australia, the National Affordable Housing Summit Group developed their definition of affordable housing as housing that is “…reasonably adequate in standard and location for lower or middle income households and does not cost so much that a household is unlikely to be able to meet other basic needs on a sustainable basis.” Affordable housing in the United Kingdom includes “Social rented and intermediate housing, provided to specified eligible households whose needs are not met by the market.”

There has been an increase among policy makers in affordable housing as the price of housing has increased dramatically creating a crisis in affordable housing.

Affordable housing is a controversial reality of contemporary life, for gains in affordability often result from expanding land available for housing or increasing the density of housing units in a given area.

Many housing rights groups also attempt to combat social and political issues which relate to access to quality affordable housing such as housing discrimination, redlining, and lack of access to amenities in areas with affordable housing including food deserts and transit deserts.

Affordable housing needs can be addressed through public policy instruments that focus on the demand side of the market, programs that help households reach financial benchmarks that make housing affordable.

In some countries, public housing is focused on providing affordable housing for low-income earners while in others, such as Singapore, citizens across a wide range of incomes live in public housing.

Oceaneering International

Oceaneering International, Inc. is a subsea engineering and applied technology company based in Houston, Texas, U.S. that provides engineered services and hardware to customers who operate in marine, space, and other environments.

Oceaneering was founded in 1964 with the incorporation of World Wide Divers, Inc., one of three companies who merged in 1969 to operate under the name Oceaneering International, Inc. The merged companies were World Wide Divers, Inc., California Divers, Inc., and Can-Dive Services Ltd. World Wide Divers, Inc. was owned by Mike Hughes and Johnny Johnson.

In the early 1970s, Oceaneering supported considerable research into ways to increase safety of their divers and general diving efficiency, including their collaboration with Duke University Medical Center to explore the use of trimix breathing gas to reduce the incidence of high-pressure nervous syndrome.

A dive team from Oceaneering salvaged three of the four propellers from the RMS Lusitania in 1982.

Oceaneering teamed up with the Canadian company GRI Simulations to design and produce the ROV simulators they utilize for training, development of procedures, and equipment staging.

On April 22, 2010, three Oceaneering ROV crews aboard the Oceaneering vessel Ocean Intervention III, the DOF ASA Skandi Neptune and the Boa International Boa Sub C began to map the seabed and assess the wreckage from the Deepwater Horizon oil spill.

OES was formed in 1992 when Oceaneering International purchased Eastport International, Inc., which specialized in underwater remotely operated vehicles and had recently been contracted by Universal Studios Florida to redesign and build the animatronic sharks for its Jaws attraction.

Forum Energy Technologies Stock Forecast, Price & News

Forum Energy Technologies, Inc. is a global oilfield products company.

THe firm serves the drilling, downhole, subsea, completions, and production sectors of the energy industry.

It operates through following segments: Drilling and Downhole, Completions, Production, and Corporate.

The Drilling and Downhole segment provides services to the drilling, well construction, artificial lift, and subsea energy construction and services markets.

The Completions segment offers services to the coiled tubing, well stimulation, and intervention markets.

The Production segment designs, manufactures, and supplies equipment and services for production and infrastructure markets.

The Corporate segment covers selling, general, and administrative expenses.

Forum Energy Technologies, Inc.

Forum Energy Technologies, Inc. Offer to Exchange any and all of its 6.250% Senior Notes due 2021 for.

Solicitation of Consents in respect of the Indenture governing the Old Notes.

Excludes accrued and unpaid interest, which will be paid in addition to the Exchange Consideration.

For the benefit of Holders of Old Notes validly tendered at or prior to the Early Tender Time, on a pro rata basis based on the principal amount of Old Notes so tendered.

Banks and brokers call: 269-5550.Toll Free: 864-7961.

Forum Energy Technologies

Forum Energy Technologies is an international oilfield products company, serving the subsea, drilling, completion, production and infrastructure sectors of the oil and natural gas industry.

It was formed in the summer of 2010 in a five-way merger among Forum Oilfield Technologies, Triton Group, Subsea Services International, Global Flow Technologies and Allied Technology.

Drilling & Subsea: subsea solutions, downhole products, drilling products.

Production & Infrastructure: flow equipment, surface process and pipeline equipment, valve solutions.

Dennis Uy’s Udenna Corporation bought 100 million common shares of Atok-Big Wedge Co. Inc. at the negotiated price of P2.00 per share or a total of P200,000,000.

Atok-Big Wedge Co, Inc. a listed corporation in PSE, has 20% ownership of United Kingdom-based Forum Energy Ltd. which has the right of oil exploration in SC72 in the west Philippine Sea.

Forum Energy Ltd. has an ongoing talks with China for joint oil exploration after President Duterte a close friend of Dennis Uy lift the moratorium on oil exploration.

2022-03-16.Dahua Technology Helps Protect Wetland Ecology And Bird MigrationOn the south bank of the Yangtze River, a unique wetland ecosystem breeds a variety of fish and aquatic animals.

Every autumn, this wetland attracts nearly 700,000 migratory birds for the winter.

They live in harmony with lakes and fields, creating a beautiful picture of nature.

Due to the complex terrain of the wetland and the huge number of migratory birds, it has been extremely difficult for local staff to manually take care of the reserve.

Dahua Technology

Zhejiang Dahua Technology Co., Ltd. is a partially state-owned publicly traded company based in Binjiang District, Hangzhou, which sells video surveillance products and services.

Dahua Technology has more than 18,000 employees all over the world.

Dahua Technology is majority owned and fully controlled by Fu Liquan and his wife Chen Ailing.

As of 31 December 2020, Fu owned 34.18% shares as the largest shareholder, while Chen owned 2.38%. According to its 2020 annual financial report, Dahua Technology is also partially state-owned by Central Huijin Asset Management and China Galaxy Securities Co., Ltd. at 1.05% and 1.82 respectively.

According to internet provider Level 3 Communications, the most commonly infected devices in this botnet were Dahua and Dahua OEM cameras and DVRs. Nearly one million Dahua devices were infected with the BASHLITE malware.

In March 2021, the Federal Communications Commission declared that Dahua services and equipment “Pose an unacceptable risk to U.S. national security.” In response, The Intercept said, “The U.S. government has not provided the public with any evidence that Dahua and Hikvision are spying on customers.”

In September 2021, Dahua acknowledged an identity authentication bypass vulnerability affecting over 30 device models that, if exploited, can allow attackers to “Bypass device identity authentication by constructing malicious data packets.” In October 2021, TechCrunch reported that The Home Depot and Best Buy stopped selling Lorex-branded Dahua and Ezviz products.

Axis Communications

Axis Communications Please upgrade to the new Edge browser, or use Chrome, Firefox or Safari, before continuing.

Internet Explorer will not support the best shopping experience on the ADI Digital Branch site after March 12.

Axis Communications

In 1996, Axis Communications introduced the industry’s first network camera, the AXIS 200.

In 2008, Axis Communications announced together with Bosch and Sony that the companies will cooperate in order to standardize the interface of network video products and form a new industry standards body called ONVIF. Axis Communications introduced its first product with ONVIF support in 2009, the AXIS P3301.

ARTPEC is an application-specific integrated circuit developed by Axis Communications which powers many Axis devices.

Axis Communications sells a full-featured video management software which it markets under the name AXIS Camera Station.

Axis Camera Application Platform, an open API, enables development of applications by third parties that can be downloaded and installed on Axis products.

In 2017, Axis Communications introduced its first radar, the D2050-VE, which allowed for minimization of false alarms, analytics, classification of objects, and more auto-tracking capabilities for Axis PTZ Cameras.

In October 2021, cybersecurity research firm Nozomi Networks published “Three new vulnerabilities affecting all Axis devices based on the embedded AXIS OS.” Axis and Nozomi collaborated throughout the research and disclosure process, with Nozomi publishing a statement from Axis in its announcement of the vulnerability.

Axis Communications Online Academy

Discovering AXIS Loss Prevention Suite Learn how the analytics apps offered in the AXIS Loss Prevention Suite can help business owners reduce theft and shrinkage.

Introduction to AXIS Camera Station End-to-End Solutions Dive into a case story to get a feeling for how you can design an AXIS Camera Station surveillance system from scratch.

Axis network camera naming convention Showcasing how the Axis product name reflects different product specifications in a standardized way.

Discovering AXIS Store Optimization Suite Learn how the analytics apps offered in AXIS Store Optimization Suite can improve store performance and customer experience.

Axis network camera product types Learn all about the different Axis camera types and and their strengths in different environments.

Exploring Axis perimeter protection solutions Learn how to master video analytics for perimeter surveillance! Combine Axis network cameras, speakers and video management software to protect large premises.

Fiber optics with Axis products Learn why fiber optics are so essential to the infrastructure powering Axis products, and how they affect system design.

The new AXIS W101 Body Worn Camera is “The body worn camera for everyone.” Learn more.

Ly/3gGuRzzSince launch, continuous enhancements have made the body worn solution more flexible than ever.

Ly/3sacwjKHow can body worn solutions be used to support healthcare or retail? Learn more.

Easily add more cameras and connected devices to your surveillance solution with AXIS Companion.

Ly/3dTT5oDFlexibility at the heart of the body worn camera solution.

Ly/3b1GdZmAxis body worn solutions achieve the ultimate flexibility through open architecture.

Ly/3Gt9wEiAXIS Camera Station makes it easy to install, use, and maintain end-to-end solutions.

Virtus Investment Partners Closes On Acquisition Of Stone Harbor Investment Partners

HARTFORD, Conn., Jan. 3, 2022 /PRNewswire/ – Virtus Investment Partners, Inc., which operates a multi-boutique asset management business, today completed the previously announced acquisition of Stone Harbor Investment Partners, a premier manager of emerging markets debt, multi-asset credit, global corporates, and other strategies with $14.5 billion1 of assets under management.

“Their institutional-quality emerging markets debt capabilities, under the leadership of Peter Wilby, Managing Partner and co-Chief Investment Officer and Jim Craige, co-CIO and Head of Emerging Markets, are well-respected among clients and consultants and highly complementary to our other fixed-income capabilities. We are pleased that Stone Harbor has joined as one of our distinctive investment managers.”

As a boutique affiliate, Stone Harbor will maintain autonomy over its investment processes, brand and culture, ensuring continuity for its clients, consultants, and distribution partners, who will collaborate with the same investment teams, including Wilby, Craige, David Torchia, Head of Multi-Asset Credit, and other key individuals who have entered into long-term employment agreements.

About Stone Harbor Stone Harbor Investment Partners, LLC is a global institutional fixed-income investment manager specializing in credit and asset allocation strategies.

About Virtus Investment Partners Virtus Investment Partners, Inc. is a distinctive partnership of boutique investment managers singularly committed to the long-term success of individual and institutional investors.

The company provides investment management products and services through its affiliated managers and select subadvisers, each with a distinct investment style, autonomous investment process, and individual brand.

Virtus Investment Partners offers access to a variety of investment styles across multiple disciplines to meet a wide array of investor needs.

Virtus Investment Partners

Virtus Investment Partners, Inc. operates a multi-manager asset management business, comprising a number of individual affiliated managers, each having its own investment process and brand, and the services of unaffiliated subadvisers.

Virtus Investment Partners, formerly known as Phoenix Investment Partners, Ltd., was formed on November 1, 1995 through a reverse merger with Duff & Phelps Investment Management Co., at the time the investment management affiliate of Duff & Phelps Corporation.

In May 2005, Phoenix Investment Partners acquired the remaining minority interest in Seneca Capital Management and in September of that year acquired the remaining minority interest in Kayne Anderson Rudnick, thereby increasing ownership of both companies to 100%. In May 2006, Phoenix Investment Partners adopted the Harris Insight Funds from Harris Investment Management, Inc. [edit].

In February 2008, Phoenix announced it would spin-off Phoenix Investment Partners as an independent asset management company through a pro-rata dividend of Phoenix Investment Partners’ common stock to Phoenix’s shareholders.

In October 2012, Virtus completed the acquisition of Rampart Investment Management, a registered investment advisor specializing in options strategies.

Virtus completed a majority investment in Sustainable Growth Advisers, an investment manager headquartered in Stamford, Connecticut that specializes in high-conviction U.S. and global growth equity portfolios, in July 2018.

Duff & Phelps Investment Management Co. pursues specialized investment strategies by identifying attractive opportunities through active management and fundamental research, while striving to manage the associated risks.

Virtus Investment Partners Declares Quarterly Cash Dividend On Common Stock

PRNewswire/ – Virtus Investment Partners, Inc., which operates a multi-boutique asset management business, today announced that its Board of Directors has declared a quarterly cash dividend of $1.50.

Per common share for the first quarter of 2022.The dividend will be paid on May 13, 2022.

About Virtus Investment Partners, Inc.Virtus Investment Partners is a distinctive partnership of boutique investment managers singularly committed to the long-term success of individual and institutional investors.

We provide investment management products and services from our affiliated managers, each with a distinct investment style and autonomous investment process, as well as select subadvisers.

Investment solutions are available across multiple disciplines and product types to meet a wide array of investor needs.

Additional information about our firm, investment partners, and strategies is available at virtus.com.

View original content to download multimedia:https://www.

Virtus Investment Partners Reports Preliminary January 31, 2022 Assets Under Management

PRNewswire/ – Virtus Investment Partners, Inc. today reported preliminary assets under management of $188.9 billion.

Of other fee-earning assets, which are not included in assets under management.

Includes $14.1 billion of assets under management related to the January 1, 2022 acquisition of Stone Harbor Investment Partners.

About Virtus Investment Partners, Inc.Virtus Investment Partners is a distinctive partnership of boutique investment managers singularly committed to the long-term success of individual and institutional investors.

We provide investment management products and services from our affiliated managers, each with a distinct investment style and autonomous investment process, as well as select subadvisers.

Investment solutions are available across multiple disciplines and product types to meet a wide array of investor needs.

Additional information about our firm, investment partners, and strategies is available at virtus.com.

Vestiaire Collective On The App Store

Every week, we add designer items from brands like Gucci, Prada Louis Vuitton, Burberry, Fendi and Dior.

Personalized notification for designer fashion items you’re looking for.

Join the designer fashion revolution now and discover preloved items sold by your community – or sell your own designer clothing, shoes, or even sneakers, straight from your phone.

Once your item has sold, you will receive a pre-paid shipping label to send the item to our HQ free of charge.

JOIN THE FASHION ACTIVIST COMMUNITY. We’re driving positive change in the fashion world – by revolutionizing the way we shop designer items.

Support a sustainable way of shopping designer items.

Whether you’re after a Louis Vuitton bag or want to sell your Gucci dress, download the Vestiaire Collective app now to get started.

Vestiaire Collective Is Buying Resale Platform Tradesy

Vestiaire Collective, the Paris-based resale company, is buying Tradesy, a California-based competitor, signalling further consolidation in resale as the market heats up.

Max Bittner, Vestiaire Collective’s chief executive, and Fanny Moizant, the company’s founder and president will stay on in the roles for both companies, while Tradesy founder Tracy DiNunzio, will become chief executive of the US operations of Tradesy and Vestiaire Collective.

Tradesy and Vestiaire Collective both operate as peer-to-peer marketplaces – as opposed to buying luxury goods from sellers, like The RealReal.

Vestiaire’s acquisition of Tradesy comes just as the resale market is going through consolidation.

The global resale market hit $130 billion in 2020, according to a BoF Insights report on the resale industry, and is expected to grow at a compounded annual growth rate of 16 percent.

In June 2021, craft marketplace Etsy bought Gen Z resale platform Depop for $1.6 billion.

In September 2021, Goat Group, the parent company of sneaker resale sites Goat and Flight Club, invested in menswear resale platform Grailed, with the two competitors agreeing to share expertise.

Tuberculosis Vaccination

BCG is a vaccine for TB. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common.

BCG vaccine does not always protect people from getting TB. If you were vaccinated with BCG, you may have a positive reaction to a TB skin test.

This reaction may be due to the BCG vaccine itself or due to infection with the TB bacteria.

Your positive reaction is more likely to mean you have been infected with TB bacteriaMore.

Tuberculosis Vaccines

Tuberculosis vaccines are vaccinations intended for the prevention of tuberculosis.

Today, the only effective tuberculosis vaccine in common use is the Bacillus Calmette-Guérin vaccine, first used on humans in 1921.

New vaccines are being developed by the Tuberculosis Vaccine Initiative, including TBVI and Aeras.

Development of a new prime vaccine to replace BCG. Development of sub-unit or booster vaccines to supplement BCG Pre-infection.

Since the BCG vaccine does not offer complete protection against TB, vaccines have been designed to bolster BCG’s effectiveness.

Progression of vaccine designs relies heavily on outcomes in animal models.

Most animal testing for TB vaccines has been conducted on murine, bovine and non-primate species.

A Look At Each Vaccine: Tuberculosis Vaccine

The tuberculosis vaccine is rarely used in the United States.

It is only recommended for children living with someone who is actively infected with TB who either cannot take antibiotics to treat the infection or is infected with a strain of TB that is highly resistant to all antibiotics.

Decisions regarding this vaccine are typically made in consultation with a local TB control program.

In most other countries, the vaccine for tuberculosis, known as the BCG vaccine, is used more commonly because of the frequency of tuberculosis.

Tuberculosis Vaccines: Time To Think About The Next Generation

Efforts over the last 2 decades have led to a rich research and development pipeline of tuberculosis vaccines.

These vaccines aim at prevention of active TB, with most of them being considered for preexposure with recent additions for postexposure or multistage administration.

A few therapeutic vaccines are under clinical assessment, as well.

Preexposure vaccination with the licensed TB vaccine BCG prevents severe forms of TB in children but not in adolescents and adults.

The current vaccine pipeline does not include strategies which prevent or eliminate infection with the causative agent Mycobacterium tuberculosis.

Rather in a best-case scenario, they are quantitatively superior to BCG in preventing active TB over prolonged periods of time, ideally lifelong in the face of latent Mtb infection.

Qualitatively superior vaccines should be capable of preventing or eliminating Mtb infection, in this way eliminating the risk of TB reactivation.

History Of Vaccines

Tuberculosis is a disease caused by the tuberculosis bacteria, Mycobacterium tuberculosis.

Symptoms of active tuberculosis infection include cough lasting several weeks, coughing up sputum or blood, fever, night sweats, and pain in the chest.

People with latent tuberculosis infections do not spread tuberculosis bacteria to others around them.

People with active tuberculosis disease are treated with antibiotics and other drugs that kill or control the tuberculosis bacteria.

People with latent tuberculosis can be treated with antibiotics to ensure that they do not later become ill with active tuberculosis.

Though the route of tuberculosis infection is respiratory, and the main symptoms are usually respiratory, tuberculosis bacteria can spread to and infect other parts of the body, such as the bones and brain.

The hope is to develop a vaccine that prevents infection with tuberculosis, which would reduce the great burden of disease global and also reduce transmission of the TB bacteria.

VPM1002 Tuberculosis Vaccine

The VPM1002 vaccine is a genetically modified BCG vaccine derived from the Mycobacterium Bovis BCG subtype Prague characterized as rBCGÄureC::Hly+.

Studies on mice show that the BCG vaccine can protect against tuberculosis and viral infections of the respiratory tract.

In 2012, the company began developing the vaccine and the Serum Institute of India Pvt. Ltd. , one of the largest vaccine manufacturers worldwide.

July 27, 2021 – Scientists from the Hackensack Meridian Center for Discovery and Innovation were awarded $6.4 million from the National Institutes of Health to pursue innovative new tuberculosis vaccine concept.

March 23, 2020 – A Phase III study investigates whether the vaccine candidate VPM1002, originally developed against tuberculosis by scientists at the Max Planck Institute for Infection Biology, is also effective against infection with SARS-CoV-2.

PriMe is a multicenter, double-blind, randomized, active-controlled Phase III study to evaluate the efficacy and safety of the vaccine candidate VPM1002 compared to BCG for the prevention of Mycobacterium tuberculosis infection in HIV-exposed and HIV-unexposed newborn infants.

The TB vaccine included in this new clinical study offers a chance to contain the accelerating spread of multi-drug-resistant TB. Treating TB requires a multi-drug course of treatment lasting up to 6 months and longer when treating drug-resistant TB. VPM1002 Tuberculosis Vaccine Dosage.

Tuberculosis Vaccines Market Analysis 2022 With Top Leaders, Size, CAGR Of 2.8%, Share, Growth, Technical Industry Vision Throughout The World Till 2028

Mar 14, 2022 – Report on Global “Tuberculosis Vaccines Market” 2022-2028 mainly presents value, growth, volume and market share by players, by size, by product type, by regions, by consumers and also their price change details.

Due to the COVID-19 pandemic, global Tuberculosis Vaccines market size is estimated to be worth USD 76 million in 2022 and is forecast to a readjusted size of USD 90 million by 2028 with a CAGR of 2.8% during the review period.

Fully considering the economic change by this health crisis, Immunotherapeutic Vaccines accounting for % of the Tuberculosis Vaccines global market in 2021, is projected to value USD million by 2028, growing at a revised % CAGR in the post-COVID-19 period.

China Tuberculosis Vaccines market size is valued at USD million in 2021, while the US and Europe Tuberculosis Vaccines are USD million and USD million, severally.

The report covers the key players of the industry including Company Profile, Product Specifications, Production Capacity/Sales, Revenue, Price and Gross Margin Sales with a thorough analysis of the market’s competitive landscape and detailed information on vendors and comprehensive details of factors that will challenge the growth of major market vendors.

To study and analyze the global Tuberculosis Vaccines market size by company, key regions/countries, products and application, history data from 2018 to 2022, and forecast to 2028.

Focuses on the key global Tuberculosis Vaccines manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.

ONO PHARMA USA, INC.

ONO PHARMA USA, INC. was established in 1998 as the US subsidiary of Ono Pharmaceutical Co., Ltd., an R&D-oriented pharmaceutical company with a headquarter in Osaka, Japan that was founded in 1717 and have made progress for more than 300 years in our commitment to relieving pain of patients and focus on their health improvement and succeeded in delivery of “First in class” medicines to patients such as OPDIVO®.

After the World War II, ONO made a full-edged entry into the OTC drug market.

Prostaglandins came to ONO’s knowledge through the special lecture of Professor Sune K. Bergström of Sweden’s Lund University in 1965, when ONO was still a small company with 20 researchers.

In July 2014, when 22 years passed since the discovery of PD-1, ONO obtained marketing approval for OPDIVO for the first time in the world and in September of the same year launched the drug on the market.

ONO has discovered new drug discovery seeds and developed breakthrough new drugs initiated through collaboration with research institutes including universities since before the words “Open innovation” started to become widely used.

ONO Pharma Foundation promote research to help build a bedrock for innovation through research grants to researchers overseas.

Ono Venture Investment, Inc. is the corporate venture capital arm of ONO. To pursue ONO’s corporate philosophy “Dedicated to the Fight against Disease and Pain”, OVI headquartered in San Francisco Bay area, one of the centers of start-up companies, is actively seeking equity-investment opportunities.

Ono Pharmaceutical

Designing manufacturing processes that incorporate quality control.

Ono, like many of its counterparts in the industry, has accelerated its efforts to introduce quality control to the production of pharmaceutical ingredients.

In the modern era, there is also a product quality mandate.

The introduction of new guidelines known as the ICHQ Quartet and promulgation of the Quality by Design(QbD) concept have further accelerated the demand for detailed investigations into product quality.

In order to maintain and secure quality, a company must have a deep understanding of not only its manufacturing processes, but also the relationships among multiple manufacturing parameters.

Within a matrix created by the interactions among these multiple parameters, a Design Space that enables the production of pharmaceutical ingredients with assured quality is set, and production occurs within the framework of that space.

By taking a statistical approach to those manufacturing processes that have an effect on product quality, Ono is implementing a structure that will ensure robust processes.

Ono Pharmaceutical

Ono Pharmaceutical Co., Ltd. is one of the largest pharmaceutical companies in Japan.

It is headquartered in Chuo-ku, Osaka, Japan, with its major plants in Higashinari-ku, Osaka, and Fujinomiya, Shizuoka.

Its central research institute at Minase, Shimamoto-cho, Mishima District, Osaka.

Ono Pharmaceutical’s roots go back to 1717 when Ichibei Ono started his dealer business of pharmaceuticals in Osaka.

His business expanded and changed its name a few times, and became Ono Pharmaceutical Industrial Co., Ltd. in 1948.

Ono has been listed in Tokyo Stock Exchange since 1963.

Tasuku Honjo of Kyoto University, who received the Nobel Prize later in 2018, is marketed by both Ono Pharmaceutical and Bristol-Myers Squibb.

Ono Pharma Foundation

Ono Pharma Foundation carries out the Ono Pharma Breakthrough Science Initiative Awards Program, a competitive awards program to support scientific research projects throughout the United States.

Ono initiative is the embodiment of our commitment to accelerate open innovation by supporting high-risk and high-reward science research projects, which have potential to lead to science discoveries/solutions and, possible, based on further research, to breakthrough treatments for patients.

Identify and help develop innovative research proposals and results that could lead to the development of breakthrough treatment solutions for patients.

Support academic research and the career development of promising young and established scientists.

Build strong relationships within the community in order to lead to transformative research aligned with the Ono Initiative’s goals.

The purpose of the Ono Initiative is to support scientist Principal Investigators with creative ideas in selected scientific research fields with the mission of seeking discoveries/solutions and development of high impact science.

Noront Resources Ltd. Stock Quote

Noront Resources Ltd. engages in the development, exploration, and acquisition mineral properties.

The company was founded by Richard E. Nemis on November 14, 1980 and is headquartered in Toronto, Canada.

Noront Resources Stock Forecast, Price & News

Noront Resources Ltd., a resource company, engages in the acquisition, development, and exploration of base and precious metals in Canada.

The company’s flagship property is the Eagle’s Nest project located in the James Bay Lowlands, Ontario.

The company was formerly known as White Wing Resources Inc. and changed its name to Noront Resources Ltd. in July 1983.

Noront Resources Ltd. was incorporated in 1980 and is headquartered in Toronto, Canada.

Noront Announces Shareholder Approval Of Plan Of

TORONTO, March 15, 2022 – Noront Resources Ltd. is pleased to announce that shareholders of the Company have overwhelmingly approved the proposed plan of arrangement involving Wyloo Metals Pty Ltd. and its wholly-owned subsidiary, Wyloo Canada AcquisitionCo Pty Ltd. at the special meeting of Shareholders held earlier today.

To become effective, the Arrangement required the approval of: at least two-thirds of the votes cast by Shareholders present virtually or represented by proxy at the Special Meeting; and a simple majority of the votes cast by Shareholders present virtually or represented by proxy at the Special Meeting, other than the votes cast by Mr. Alan Coutts and the Wyloo Parties, which were excluded pursuant to Multilateral Instrument 61-101 – Protection of Minority Shareholders in Special Transactions.

Such Automatic Squeeze-Out is intended to protect Shareholders by ensuring that all Common Shares will be purchased by Wyloo Canada under the Arrangement if, after the completion of the Arrangement, Shareholders would not hold a sufficient percentage of the outstanding Common Shares for Noront to meet the continued listing requirements of the TSX Venture Exchange.

Completion of the Arrangement remains subject to, among other things, satisfaction of all conditions precedent to closing the Arrangement, including the final approval of the Ontario Superior Court of Justice and TSX Venture Exchange.

Noront also announces that it has executed an amending agreement dated March 15, 2022 with Wyloo Metals, Wyloo Canada and Wyloo AcquisitionCo to amend the arrangement agreement, effective December 22, 2021, as amended.

Pursuant to the amendment, Wyloo Canada has assigned, and Wyloo AcquisitionCo has assumed, the obligations of Wyloo Canada under the Arrangement Agreement, such that Wyloo AcquisitionCo will become the purchaser under the Plan of Arrangement.

Forward-looking information and statements include, but are not limited to, information and statements regarding the Arrangement, regulatory and Court approval of the Arrangement, the timing and ability of Noront to complete the Arrangement, the timing and ability of Noront to satisfy the conditions precedent to completing the Arrangement, including obtaining the final Court approval as set forth in the Arrangement Agreement, the ability of Shareholders to continue to have an interest in the Company following the closing of the Arrangement, the number of Retention Elections expected to be submitted prior to the Retention Election Deadline, the potential of the Ring of Fire, and projections about the world’s transition to a lower carbon future.

Shareholders Approved Plan Of Wyloo Metals And Noront

THUNDER BAY – MINING – Noront Resources Ltd. is pleased to announce that shareholders of the Company have overwhelmingly approved the proposed plan of arrangement involving Wyloo Metals Pty Ltd. and its wholly-owned subsidiary, Wyloo Canada AcquisitionCo Pty Ltd. at the special meeting of Shareholders held earlier today.

The Minority Shareholders of the Company also approved the interest share proposal, pursuant to which the Company may elect to issue common shares to settle any accrued interest under the terms of a loan agreement among the Company and Wyloo Canada Holdings Pty Ltd., a wholly-owned subsidiary of Wyloo Metals.

To become effective, the Arrangement required the approval of: at least two-thirds of the votes cast by Shareholders present virtually or represented by proxy at the Special Meeting; and a simple majority of the votes cast by Shareholders present virtually or represented by proxy at the Special Meeting, other than the votes cast by Mr. Alan Coutts and the Wyloo Parties, which were excluded pursuant to Multilateral Instrument 61-101 – Protection of Minority Shareholders in Special Transactions.

Shareholders who wish to make a Retention Election should be advised that if, following the Retention Election Deadline, less than 20% of the issued and outstanding Common Shares are the subject of a Retention Election, Wyloo AcquisitionCo will acquire all of the Common Shares not already owned or controlled by the Wyloo Parties, including those Common Shares that are the subject of a Retention Election.

Such Automatic Squeeze-Out is intended to protect Shareholders by ensuring that all Common Shares will be purchased by Wyloo Canada under the Arrangement if, after the completion of the Arrangement, Shareholders would not hold a sufficient percentage of the outstanding Common Shares for Noront to meet the continued listing requirements of the TSX Venture Exchange.

Noront also announces that it has executed an amending agreement dated March 15, 2022 with Wyloo Metals, Wyloo Canada and Wyloo AcquisitionCo to amend the arrangement agreement, effective December 22, 2021, as amended.

Pursuant to the amendment, Wyloo Canada has assigned, and Wyloo AcquisitionCo has assumed, the obligations of Wyloo Canada under the Arrangement Agreement, such that Wyloo AcquisitionCo will become the purchaser under the Plan of Arrangement.

Stockwatch

Under the terms of the arrangement, shareholders are being given the opportunity, in respect of all or a portion of their common shares of the company, to: receive a cash consideration of $1.10 per common share; or retain their common shares and remain as shareholders following the completion of the arrangement by making an election to retain their common shares.

Computershare Investor Services Inc., in its capacity as depositary under the arrangement, has advised that 3,330,661 common shares are subject to retention elections as of the interim election deadline, representing approximately 0.6 per cent of the issued and outstanding common shares; and.

Shorecrest Group, in its capacity as proxy solicitation agent under the arrangement, has advised that, based on information supplied by various brokers and market intermediaries as of the interim election deadline, that additional retention elections for an additional 45,138,542 common shares are pending, representing approximately 8.0 per cent of the issued and outstanding common shares.

Together, the existing retention elections and pending retention elections represent an aggregate of 48,469,203 common shares, representing approximately 8.6 per cent of the issued and outstanding common shares as of the interim election deadline.

Shareholders who do not make a retention election prior to the retention election deadline will be deemed under the arrangement to have elected to receive the cash consideration for all their common shares.

Shareholders who wish to make a retention election should be advised that if, following the retention election deadline, less than 20 per cent of the issued and outstanding common shares are the subject of a retention election, Wyloo AcquisitionCo will acquire all of the common shares not already owned or controlled by the Wyloo parties, including those common shares that are the subject of a retention election.

Such automatic squeeze-out is intended to protect shareholders by ensuring that all common shares will be purchased by Wyloo Canada under the arrangement if, after the completion of the arrangement, shareholders would not hold a sufficient percentage of the outstanding common shares for Noront to meet the continued listing requirements of the TSX Venture Exchange.

Nootropic Drinks & Brain Enhancing Supplement Stacks From Koios

Don’t miss out on a chance to save big with our Koios subscription packages.

Life can be difficult and traffic is dangerous and time consuming.

Build your own monthly subscription of your favorite KOIOS products and have them delivered to your door each month.

You will not only save money on KOIOS, but you will save money on gas as well.

You can cancel at anytime without hassle, we promise.

You have earned the right to sit back and be served.

Koios Beverage Corp. Announces Shares For Service Issuance

DENVER and VANCOUVER, British Columbia, March 16, 2022 – Koios Beverage Corp. announces the issuance of 172,662 common shares at a price of $0.37 per common share to Blackbeard Beverages, LLC in respect of a distribution agreement to sell the Company’s beverage products directly to distributors and retailers in new territories and distributors and retailers not currently selling the Company’s beverage products.

About Koios Beverage Corp. The Company is an emerging functional beverage company which has an available distribution network of more than 4,400 retail locations across the United States in which to sell its products.

The forward-looking information reflects management’s current expectations based on information currently available and are subject to a number of risks and uncertainties that may cause outcomes to differ materially from those discussed in the forward-looking information.

Although the Company believes that the assumptions and factors used in preparing the forward-looking information are reasonable, undue reliance should not be placed on such information and no assurance can be given that such events will occur in the disclosed time frames or at all.

New risk factors emerge from time to time, and it is impossible for the Company’s management to predict all risk factors, nor can the Company assess the impact of all factors on Company’s business or the extent to which any factor, or combination of factors, may cause actual results to differ from those contained in any forward-looking information.

The forward-looking information included in this news release are made as of the date of this news release and the Company expressly disclaims any intention or obligation to update or revise any forward-looking information whether as a result of new information, future events or otherwise, except as required by applicable law.

This news release may contain trademarked names of third-party entities typically in reference to relationships had by Koios with such third-party entities as referred to in this release and/or client/vendor/service provider parties whose relationship with Koios is/are referred to in this release.

Koios Beverage Corp. Amends Convertible Debenture

DENVER and VANCOUVER, British Columbia, March 11, 2022 – Koios Beverage Corp. announces that it has amended the terms of an unsecured convertible debenture previously issued on February 12, 2021 to an arm’s length investor in the principal amount of $600,000.

The Convertible Debenture bears interest at the rate of 15% per annum and matured on October 1, 2021; under the amended terms, the Convertible Debenture will now mature on October 1, 2022 and it will be convertible into units of the Company with a conversion price of $0.13 per Unit.

The total principal amount and all accrued and unpaid interest outstanding under the Convertible Debenture is $857,846.

The amendment to the Convertible Debenture will allow the Company to preserve its capital for operational activities.

The Convertible Debenture described in this press release have not been and will not be registered under the United States Securities Act of 1933, as amended, or any state securities laws and may not be offered or sold within the United States or to, or for the account or benefit of, “U.S. persons,” as such term is defined in Regulation S under the U.S. Securities Act, unless an exemption from such registration is available.

About Koios Beverage Corp. The Company is an emerging functional beverage company which has an available distribution network of more than 4,400 retail locations across the United States in which to sell its products.

Forward-looking information in this news release includes statements regarding: Statements pertaining to the conversion of the Convertible Debenture.

Koios Beverage Corp. Announces Shares For Service Issuance – Goldea Capital

DENVER and VANCOUVER, British Columbia, March 16, 2022 – Koios Beverage Corp. announces the issuance of 172,662 common shares at a price of $0.37 per common share to Blackbeard Beverages, LLC in respect of a distribution agreement to sell the Company’s beverage products directly to distributors and retailers in new territories and distributors and retailers not currently selling the Company’s beverage products.

About Koios Beverage Corp. The Company is an emerging functional beverage company which has an available distribution network of more than 4,400 retail locations across the United States in which to sell its products.

Forward-looking information in this news release includes statements regarding: Statements pertaining to the distribution agreement with Blackbeard.

The forward-looking information reflects management’s current expectations based on information currently available and are subject to a number of risks and uncertainties that may cause outcomes to differ materially from those discussed in the forward-looking information.

Although the Company believes that the assumptions and factors used in preparing the forward-looking information are reasonable, undue reliance should not be placed on such information and no assurance can be given that such events will occur in the disclosed time frames or at all.

New risk factors emerge from time to time, and it is impossible for the Company’s management to predict all risk factors, nor can the Company assess the impact of all factors on Company’s business or the extent to which any factor, or combination of factors, may cause actual results to differ from those contained in any forward-looking information.

The forward-looking information included in this news release are made as of the date of this news release and the Company expressly disclaims any intention or obligation to update or revise any forward-looking information whether as a result of new information, future events or otherwise, except as required by applicable law.

Department Of Ophthalmology

Vision impairment may be caused by a loss of visual acuity, where the eye does not see objects as clearly as usual.

The World Health Organization defines “Low vision” as visual acuity between 20/70 and 20/400, with the best possible correction, or a visual field of 20 degrees or less.

Visual acuity alone cannot indicate how much a person’s life will be affected by vision loss.

Two people may have the same visual acuity, but one may be able to use his or her vision better to do everyday tasks.

A person’s functional vision can be evaluated by observing them in different settings to see how they use their vision.

Can the person scan a room to find someone or something?What lighting is best for the person to do different tasks?How does the person use his or her vision to move around in a room or outside?

Children with more severe vision impairment are more likely to have additional disabilities than are children with milder vision impairment.

Blindness And Vision Impairment

The International Classification of Diseases 11 classifies vision impairment into two groups, distance and near presenting vision impairment.

This 1 billion people includes those with moderate or severe distance vision impairment or blindness due to unaddressed refractive error, cataract, glaucoma, corneal opacities, diabetic retinopathy, and trachoma, as well as near vision impairment caused by unaddressed presbyopia.

With regards to near vision, rates of unaddressed near vision impairment are estimated to be greater than 80% in western, eastern and central sub-Saharan Africa, while comparative rates in high-income regions of North America, Australasia, Western Europe, and of Asia-Pacific are reported to be lower than 10%. Population growth and ageing are expected to increase the risk that more people acquire vision impairment.

Vision rehabilitation is very effective in improving functioning for people with an irreversible vision impairment that can be caused by eye conditions such as diabetic retinopathy, glaucoma, consequences of trauma and age-related macular degeneration.

WHO’s work is guided by the recommendations of the WHO World report on vision and the resolution on “Integrated, people-centred eye care, including preventable blindness and vision impairment” that was adopted at 73rd World Health Assembly in 2020.

Causes of blindness and vision impairment in 2020 and trends over 30 years: evaluating the prevalence of avoidable blindness in relation to “VISION 2020: the Right to Sight”.

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study.

Vision Impairment Types, Causes & Characteristics

Learn about vision impairment, including the visual impairment definition.

Discover the types of visual impairment, causes of visual impairment, and means of prevention and treatment for some forms of vision impairment.

Importantly, the World Health Organization has created a visual impairment definition to describe how severe an individual’s visual impairment is.

Characteristics of visual impairment in children should be understood and noted because there are several causes and symptoms associated with this kind of manifestation.

Children whose vision cannot be corrected with glasses or contacts may have visual impairment, resulting in either complete or partial vision loss.

Discuss prevention used for those types and discuss some of the treatments used for other types of visual impairment.

Visual impairment describes an abnormal level of eyesight and there is a wide range of impairment manifestations that differ between adults and children.

Common Eye Disorders And Diseases

The leading causes of blindness and low vision in the United States are primarily age-related eye diseases such as age-related macular degeneration, cataract, diabetic retinopathy, and glaucoma.

Other common eye disorders include amblyopia and strabismus.

Macular degeneration, often called age-related macular degeneration, is an eye disorder associated with aging and results in damaging sharp and central vision.

Glaucoma is a group of diseases that can damage the eye’s optic nerve and result in vision loss and blindness.

Amblyopia is the medical term used when the vision in one of the eyes is reduced because the eye and the brain are not working together properly.

The eye itself looks normal, but it is not being used normally because the brain is favoring the other eye.

Conditions leading to amblyopia include strabismus, an imbalance in the positioning of the two eyes; more nearsighted, farsighted, or astigmatic in one eye than the other eye, and rarely other eye conditions such as cataract.

Visual Impairment: What Is Impaired Vision?

Some only use the term to describe visual acuity, the sharpness of one’s vision.

Someone with 20/20 vision could read small letters on a Snellen eye chart that would look very blurry to someone with impaired visual acuity.

The impact of vision impairment depends on how much – and in what way – someone’s vision is impaired.

Impaired vision can be confused with low vision, which is classified by the level of visual impairment.

The WHO defines a person with low vision as having a central visual field of less than 20 degrees.

In the United States, people are considered legally blind when they have 20/200 vision or worse or a visual field less than 20 degrees.

Vision impairment can come with everyday difficulties, but people with impaired vision can still live a fulfilling, independent life.

Center For Parent Information And Resources

The Help Available under IDEA. If you suspect that your child has a visual impairment, you’ll be pleased to know there’s a lot of help available under IDEA-beginning with a free evaluation of your child.

Visual impairment, including blindness, is one of the disabilities specifically mentioned and defined in IDEA. If a child meets the definition of visual impairment in IDEA as well as the State’s criteria, then he or she is eligible to receive early intervention services or special education and related services under IDEA. To identify the EI program in your neighborhoodAsk your child’s pediatrician for a referral.

Developing a written plan of servicesIn both cases-in early intervention for a baby or toddler with a visual impairment and in special education for a school-aged child, parents work together with program professionals to develop a plan of services the child will receive based on his or her needs.

If you have a child with a visual impairment, you’ll probably find yourself dealing with a variety of eye care professionals who become involved to diagnose and address your child’s specific disability or eye condition.

Making adaptations to the environment where a child with a visual impairment lives, works, or plays makes evident sense, but it may be difficult for families, daycare providers, or school personnel to decide what kinds of adaptations are necessary to ensure the child’s safety while also encouraging his or her ability to do things independently.

Help your child explore new things with his or her senses and build up a concept of the “Whole.” For example, your child might need to be shown a banana, help you peel it, feel the banana without its skin, have a bite of it, and then help you mash it in her bowl to understand the qualities of bananas and that bananas can be eaten in different ways.

Demonstrate any assistive technology your child uses and provide any information teachers will need.

Cerebral Visual Impairment

Cerebral visual impairment is a disorder caused by damage to the parts of the brain that process vision.

A child with CVI has vision problems that are caused by their brain that can’t be explained by a problem with their eyes.

Normally, the eyes send electrical signals to the brain, and the brain turns those signals into the images you see.

If you have CVI, your brain has trouble processing and understanding these signals.

CVI is a leading cause of vision loss among kids in the United States.

For some children with CVI, vision gets better over time , but everybody is different.

If your child has CVI, make sure that they get early intervention and therapy, educational support, and other special services to help them develop and learn.

Overview, Principles And Functions

To guarantee job security, many employees know that they need to show commitment to the company and their job duties.

The HR management comes in to put measures in place that ensure that staffing levels correspond to the company’s needs and that, in the process, assure employees of their long-term positions within the organization.

Employee development is a trade-off through which human resource management saves money by avoiding the potential costs of hiring new employees.

Human resource management does not just handle the recruitment of new employees; it also oversees redundancy for companies that want to downsize.

Overall, human resource management guarantees the smooth running of employees within a company.

Employee morale is defined as the overall satisfaction, outlook, and feelings of well-being that an employee holds in the workplace.

Employee Turnover Rate.The employee turnover rate is the proportion of employees who leave the company during a certain time period.

What Is Human Resources Management: Careers, Skills, Trends

Read on to explore what human resources management is, and take a look at the careers, skills, and trends that relate to the field.

According to Kathleen Egger, a lecturer for the Master of Science in Human Resources Management program within Northeastern’s College of Professional Studies, “Human resources is not just an administrative function anymore. It is about understanding how the business itself functions so that we can then advise on the best practices moving forward.”

Learn more about earning an advanced degree in Human Resources Management.

According to the Society for Human Resource Management, it is vital for human resources staff to have a working knowledge of information technology because HR touches everyone in an organization and has to deal with many data privacy and integration issues.

Northeastern offers an expansive network of both business and nonprofit organizations that students in the Master’s in Human Resources Management program.

For those interested in advancing their human resources career or breaking into the field, earning a Master of Science in Human Resources Management or Graduate Certificate in Human Resources Management from Northeastern University could be the next step on your path toward success.

Learn more about what this degree in human resources management entails on the MS in Human Resources Management program page.

Human Resource Management: What Is It?

Human resource management is the organizational function that manages all of the issues related to the people in an organization.

Learn more about what human resource management is and how it works.

Human resource management is also a strategic and comprehensive approach to managing people and the workplace culture and environment.

The department members provide the knowledge, necessary tools, training, administrative services, coaching, legal and management advice, and talent management oversight that the rest of the organization needs for successful operation.

Acronym: HRM. HRM staff members are partially responsible for ensuring that the organization has an overall mission, vision, and values that are shared and provide an overarching reason for employees to want to work for their organization.

The HRM function is now expected to add value to the strategic utilization of employees and to ensure that employee programs recommended and implemented impact the business in positive measurable ways.

Those wishing to enter the field of HRM usually need at least a bachelor’s degree in human resource management or a related field, such as business management.

1.1 What Is Human Resources? – Human Resource Management

Most managers deal with compensation, motivation, and retention of employees-making these aspects not only part of HRM but also part of management.

Human Resource Recall Have you ever had to work with a human resource department at your job? What was the interaction like? What was the department’s role in that specific organization?

The legal environment of HRM is always changing, so HRM must always be aware of changes taking place and then communicate those changes to the entire management organization.

Besides these major roles, good communication skills and excellent management skills are key to successful human resource management as well as general management.

The website of the Society for Human Resource Management, SHRM Online1, not only has job postings in the field but discusses many contemporary human resource issues that may help the manager make better decisions when it comes to people management.

In Section 1.3 “Today’s HRM Challenges”, we go into more depth about some recent external issues that are affecting human resource management roles.

In Section 1.1.2 “The Role of HRM”, we discuss some of the skills needed to be successful in HRM. Key Takeaways Capital includes all resources a company uses to generate revenue.

Human Resource Management

Human resource management is the strategic approach to the effective and efficient management of people in a company or organization such that they help their business gain a competitive advantage.

Human resource management is primarily concerned with the management of people within organizations, focusing on policies and systems.

“Human resources management” consequently, became the dominant term for the function-the ASPA even changing its name to the Society for Human Resource Management in 1998.

Several popular media productions have depicted human resource management in operation.

Human resource management has four basic functions: staffing, training and development, motivation, and maintenance.

As Human resource management field is continuously evolving due to technology advances of the Fourth Industrial Revolution, it is essential for universities and colleges to offer courses which are future oriented.

The Society for Human Resource Management, which is based in the United States, is the largest professional association dedicated to HR, with over 285,000 members in 165 countries.

What Is Human Resource Management?

Human resource management is the practice of recruiting, hiring, deploying and managing an organization’s employees.

HRM is employee management with an emphasis on those employees as assets of the business.

In this context, employees are sometimes referred to as human capital.

Larger organizations may have more specialized roles, with individual employees dedicated to functions such as recruiting, immigration and visa handling, talent management, benefits, compensation and more.

Effectively manage change to external factors that may affect employees within the organization.

Following WWII in the United States, personnel management departments looked to the Army’s training programs and started to make employee training a point of emphasis.

The primary factor that differentiates HR from personnel management is the technological enablement of better communications and access to individual employee information.

The 8 Key Functions Of Human Resources Management

Human resource management is the recruitment, management, and development of employees to serve an organization’s goals.

The science of employee management involves using people analytics to evaluate how well your company is leveraging its talent.

Compensation management includes establishing salary ranges for positions, placing employees within the ranges based on their qualifications, and adjusting pay to recognize milestones and accomplishments.

Performance management is a continual process of evaluating how individual employees are performing, identifying areas of improvement, and recognizing achievement.

A performance management plan helps all employees work to the best of their abilities.

Administering employee benefits is a substantial part of the HR management function.

Ask employees what they want: You might assume that salary is your employees’ chief concern, while your employees might be willing to trade some of that compensation for flexibility.

Coagulopathy

Coagulopathy is a condition in which the blood’s ability to coagulate is impaired.

Of note, coagulopathies are sometimes erroneously referred to as “Clotting disorders”; a clotting disorder is a predisposition to clot formation, also known as a hypercoagulable state or thrombophilia.

Coagulopathy may cause uncontrolled internal or external bleeding.

Uncontrolled bleeding may cause damage to joints, muscles, or internal organs and may be life-threatening.

People should seek immediate medical care for serious symptoms, including heavy external bleeding, blood in the urine or stool, double vision, severe head or neck pain, repeated vomiting, difficulty walking, convulsions, or seizures.

Coagulopathy may be caused by reduced levels or absence of blood-clotting proteins, known as clotting factors or coagulation factors.

One area of treatment is managing people with major bleeding in a critical setting, like an emergency department.

Coagulopathy Causes, Symptoms, Diagnosis & Coagulopathy Treatment

Dilutional coagulopathy is usually defined as loss, consumption, or dilution of coagulation factors and occurs when blood is replaced with fluids that do not contain adequate coagulation factors.

Dilutional coagulopathy is one of the most common causes of bleeding after massive transfusion in the later phase after trauma.

In contrast to congenital bleeding disorders based on single coagulation factor deficiency, dilutional coagulopathy is related to multifactorial changes that affects thrombin generation, clot firmness, and fibrinolysis.

Fresh frozen plasma transfusion in a dose of 30 ml/kg might be useful for treatment of severe hemorrhage as adjunctive to basic treatment with coagulation factors but should only be considered after exclusion of any other factor that might influence hemostasis.

Further well-controlled studies are urgently needed to determine the effect of a targeted, laboratory-based coagulation management for treatment of dilutional coagulopathy.

Revealed no significant improvement if fresh frozen plasma was used for treatment of coagulopathy bleeding.

Treatment for a bleeding disorder depends on the cause, whether it is an acquired or inherited condition, as well as on the duration and severity of signs and symptoms.

Definition, Causes And Treatment

In case of consumptive coagulopathy or disseminated intravascular coagulopathy disorder or DIS, the over activated proteins form clot within the blood vessels and clog them.

Apart from direct coagulopathy symptoms, there are other signs which may arise later when it persists for long without administration of coagulopathy treatment.

Coagulopathy can either be genetically inherited or acquired coagulopathy in due course of someone’s life.

Since anticoagulant medicines like warfarin or Coumadin are small molecular mass, heparin will specifically obstruct the procedure of clotting, their actual presence in your blood would cause coagulopathy.

Practical removal of blood thinners would automatically reverse coagulopathy.

Delivery control pills can further assist in controlling unwarranted menstrual blood flow in women suffering from coagulopathy.

Desmoperessin acetate which is also simply known as DDVAP or also Stimate can be utilized in discharging blood thickens protein, which is regularly stored in your body to deal with minor cases of coagulopathy.

Coagulopathy In COVID-19

The COVID-19 pandemic has become an urgent issue in every country.

Based on recent reports, the most severely ill patients present with coagulopathy, and disseminated intravascular coagulation-like massive intravascular clot formation is frequently seen in this cohort.

Coagulation tests may be considered useful to discriminate severe cases of COVID-19.

The clinical presentation of COVID-19-associated coagulopathy is organ dysfunction primarily, whereas hemorrhagic events are less frequent.

Changes in hemostatic biomarkers represented by increase in D-dimer and fibrin/fibrinogen degradation products indicate the essence of coagulopathy is massive fibrin formation.

The mechanisms of the coagulopathy are not fully elucidated, however.

Keywords: COVID-19; anticoagulant; coagulopathy; coronavirus; disseminated intravascular coagulation.

Ellington Financial

Ellington Management Group, L.L.C. is a registered investment adviser with deep expertise in diversified credit, mortgage and related markets.

Ellington Financial benefits from Ellington’s more than 27-year history of investing in a broad spectrum of mortgage-backed securities and related derivatives.

We pursue value across various types of mortgage-related, consumer-related, corporate-related, and other financial assets, through investments primarily in loans and securities.

Ellington’s continued emphasis on and development of proprietary credit, interest rate, and prepayment models, as well as other proprietary research and analytics, underscores the importance it places on a disciplined and analytical approach to fixed income investing.

In addition to originating and acquiring loans, we also make strategic debt and equity investments in loan originators.

With respect to structured products including MBS, Ellington seeks investments across a wide range of sectors without any restriction as to ratings, structure, or position in the capital structure.

By rotating between and allocating among various sectors of the structured product markets and adjusting the extent to which it hedges, Ellington believes that it is able to capitalize on the disparities between these sectors as well as on overall trends in the marketplace, and therefore provide better and more consistent returns for its investors.

Ellington Financial Inc.

Ellington Financial invests in a diverse array of financial assets, including residential and commercial mortgage loans, residential and commercial mortgage-backed securities, consumer loans and asset-backed securities backed by consumer loans, collateralized loan obligations, non-mortgage and mortgage-related derivatives, equity investments in loan origination companies, and other strategic investments.

Ellington Financial is externally managed and advised by Ellington Financial Management LLC, an affiliate of Ellington Management Group, L.L.C..

Ellington Financial Stock Price, News & Info

EFC earnings call for the period ending September 30, 2021.

EFC earnings call for the period ending June 30, 2021.

EFC earnings call for the period ending March 31, 2021.

EFC earnings call for the period ending September 30, 2020.

EFC earnings call for the period ending June 30, 2020.

EFC earnings call for the period ending September 30, 2019.

EFC earnings call for the period ending June 30, 2019.

Glued Laminated Timber

Glued laminated timber, also called Glulam, is a type of structural timber composed of layers timber bonded together with durable, moisture-resistant adhesives.

Apache supplies a single large, strong, structural member by laminating together a number of smaller pieces of timber.

Glulam provides the strength and versatility of large wood members without relying on the old growth-dependent solid-sawn timbers.

Glulam reduces the overall amount of wood used when compared to solid sawn timbers since there are no knots or other small defects in the timber.

Glulam’s laminating process allows the timber to be used for much longer spans, heavier loads, and complex shapes than reinforced concrete or steel.

The high strength and stiffness of laminated timbers enable glulam beams and arches to span large distances without intermediate columns.

Glulam allows more design flexibility than with traditional timber construction.

Glued Laminated Timber

Laminated timber is a structural wood product made from strips of wood glued together.

The Finnish Glulam Association recommends that the strength class for glued laminated timber is GL 30c in accordance with Standard SFS-EN 14080.

Laminated timber is used for load-bearing structures, in both the horizontal and vertical directions, which are either left visible, or clad. As well as buildings, laminated timber is used in, e.g., load-bearing bridge construction.

Steel parts embedded in laminated timber are also fire protected for an equivalent period.

The properties of laminated timber are defined according to Finnish Standard SFS-EN 14080 and the manufacture of laminated timber according to SFS-EN 386.

Laminated timber fulfilling these standards can be used in GL strength class according to SFS-EN 1194.

Glued timber is a wood product which does not fulfil the laminated timber standards, but is made by gluing two or more items of sawn goods together.

Glued Laminated Timber

Glued laminated timber, also abbreviated glulam, is a type of structural engineered wood product constituted by layers of dimensional lumber bonded together with durable, moisture-resistant structural adhesives.

Glulam has much lower embodied energy than reinforced concrete and steel, although it entails more embodied energy than solid timber.

The high strength and stiffness of laminated timbers enable glulam beams and arches to span large distances without intermediate columns, allowing more design flexibility than with traditional timber construction.

The use of finger joints with glulam allowed for production of glulam beams and columns on large scale.

Pressure-treated glulam timbers or timbers manufactured from naturally durable wood species are well suited for creating bridges and waterfront structures.

Glulam timber is an important component in hurricane-proof building systems.

Category 5 hurricane-resistant log houses are built of glulam timber.

Photos Of Glulam Structures

Tecnologie costruttive Photographs of laminated wood structures Read our two articles: Glulam: evolution of technology.

Coniferous wood boards are generally used to manufacture glued laminated wood products … >>Read our interesting article … >>.

What Are Glulam Timbers And How They Are Used?

A glulam is made with multiple layers of solid wood lumber bonded together with high-strength adhesive to form a single structural unit.

Glulam members are sold in several standard widths and lengths and can be custom-fabricated to meet almost any design specifications.

Glulam members can be used in a wide variety of applications and for both indoor and outdoor projects.

Glulam members are classified by specific strength properties and are given a rating from a stress classification system.

The second part of the rating is the corresponding modulus of elasticity value of the glulam member.

When glulam is going to be used as a facade material or exposed element, architectural-grade appearance is highly recommended.

Glulam members should be handled carefully to prevent any damage or reduction in their structural capacity.

What Is Glued Laminated Wood?

Glued Laminated Wood is a structural material manufactured through the union of individual wood segments.

When glued with industrial adhesives, this type of wood is highly durable and moisture resistant, capable of generating large pieces and unique shapes.

Check out some advantages of using Glued Laminated Wood below.

High fire resistance: Structures made of glued laminated wood are safer than unprotected steel in fire.

When talking about “Glued laminated wood”, we talk about a wood composed of pieces glued and bonded together with parallel fibers.

Glued Laminated Wood is manufactured with an optimum degree of humidity, minimizing contraction and swelling behavior and guaranteeing the dimensional stability of the material.

What kind of projects can be used?Glulam wood is recommended for any type of construction from residential projects to industrial buildings.

Glued Laminated Timber: Disadvantages And Advantages

Advantages of glued beams Like any building material, glued beams have both advantages and disadvantages.

Homes made of plywood are easily assembled and assembled, and shrinkage and shrinkage are minimized.

The material is practically non-deformed and does not change shape.

Glued laminated wood has an optimal moisture content, which prevents rot and the growth of fungal microorganisms and harmful bacteria in it.

This material can be used to implement very complex projects.

It cannot be said that glued rafters are distinguished only by positive characteristics.

There are also disadvantages, here are some of them: 1.

Integrated Pest Management Solutions

Our products are approved for virtually every cultivated crop, from fruits and vegetables to cereal grains and nuts, from turfgrass and flowers to alfalfa and cotton.

When incorporated into an IPM program, biopesticides can be an effective solution to pest control problems in conventional, transitional or certified organic production systems.

Each MBII share will be exchanged at closing for BIOX shares at a fixed ratio of 0.088, representing a value of ~$236M. MBII stock surged 25% postmarket while BIOX stock fell 5%. This deal will combine BIOX’s expertise in bionutrition and seed care products with MBII’s leadership in the development of biological crop protection and plant health solutions.

In connection with the deal, BIOX agreed to a capital commitment with a principal amount between $37.5M and $45M in the form of a convertible loan.

At any time up to maturity, lenders will have the option to convert the loan into BIOX shares at a strike price of $18/share.

BIOX will have the option for voluntary prepayment starting 30 months after the date on which the loan is effected.

The noteholders committed to convert 75% of outstanding principal amount into BIOX shares.

The transaction is expected to close in Q3. Shareholders representing ~49% of MBII’s outstanding shares entered into customary transaction support deals, agreeing to vote their shares in favor of the merger.

On closing, MBII shareholders will own ~16M shares of BIOX, with at least 2 individuals designated by MBII to be appointed to BIOX’s board.

Marrone Bio To Sell For $236 Million To Argentinian Company Bioceres

Argentinian company Bioceres Crop Solutions Corp. has agreed to buy Davis-founded Marrone Bio Innovations Inc. in an all-stock transaction valued at $236 million.

Bioceres is based in Rosario, Argentina, and Marrone is based in Raleigh, North Carolina, with its research and development in Davis, where the company was founded.

Marrone Bio moved its headquarters to North Carolina this year.

Marrone was the Sacramento area’s sixth-largest locally based public company, with revenue of $38.4 million in 2020.

The merger is anticipated to generate $8 million in annual cost reduction, the majority of which relates to the elimination of duplicative public company expenses and consulting fees, said Marrone Bio CEO Kevin Helash, in a release.

At the close, Marrone shareholders will own about 16 million shares of Bioceres.

Founder Pam Marrone started Marrone Bio in Davis in 2006 and took it public in 2013.

Marrone Bio Stock Alert: Halper Sadeh LLP Announces Investigation Into Whether The Sale Of Marrone Bio Innovations, Inc. Is Fair To Shareholders – Lawyer Monthly

NEW YORK-(BUSINESS WIRE)-Halper Sadeh LLP, a global investor rights law firm, is investigating whether the sale of Marrone Bio Innovations, Inc. to Bioceres Crop Solutions Corp. is fair to Marrone Bio shareholders.

Under the terms of the proposed transaction, each share of Marrone Bio common stock will be exchanged at closing for ordinary shares of Bioceres at a fixed ratio of 0.088.

The investigation concerns whether Marrone Bio and its board of directors violated the federal securities laws and/or breached their fiduciary duties to shareholders by failing to, among other things: obtain the best possible consideration for Marrone Bio shareholders; determine whether Bioceres is underpaying for Marrone Bio; and disclose all material information necessary for Marrone Bio shareholders to adequately assess and value the merger consideration.

On behalf of Marrone Bio shareholders, Halper Sadeh LLP may seek increased consideration for shareholders, additional disclosures and information concerning the proposed transaction, or other relief and benefits.

Halper Sadeh LLP represents investors all over the world who have fallen victim to securities fraud and corporate misconduct.

Our attorneys have been instrumental in implementing corporate reforms and recovering millions of dollars on behalf of defrauded investors.

Marrone Bio Stock Alert: Halper Sadeh LLP Announces Investigation Into Whether The Sale Of Marrone Bio Innovations, Inc. Is Fair To Shareholders

Halper Sadeh LLP, a global investor rights law firm, is investigating whether the sale of Marrone Bio Innovations, Inc. to Bioceres Crop Solutions Corp. is fair to Marrone Bio shareholders.

Under the terms of the proposed transaction, each share of Marrone Bio common stock will be exchanged at closing for ordinary shares of Bioceres at a fixed ratio of 0.088.

The investigation concerns whether Marrone Bio and its board of directors violated the federal securities laws and/or breached their fiduciary duties to shareholders by failing to, among other things: obtain the best possible consideration for Marrone Bio shareholders; determine whether Bioceres is underpaying for Marrone Bio; and disclose all material information necessary for Marrone Bio shareholders to adequately assess and value the merger consideration.

On behalf of Marrone Bio shareholders, Halper Sadeh LLP may seek increased consideration for shareholders, additional disclosures and information concerning the proposed transaction, or other relief and benefits.

Halper Sadeh LLP represents investors all over the world who have fallen victim to securities fraud and corporate misconduct.

Our attorneys have been instrumental in implementing corporate reforms and recovering millions of dollars on behalf of defrauded investors.

Marrone Bio Innovations

Marrone Bio Innovations, Inc. leads the movement to a more sustainable world through the discovery, development and promotion of biological products for pest management and plant health.

The company has a proprietary discovery process, a rapid development platform, and a robust pipeline of pest management and plant health product candidates.

At Marrone Bio Innovations, we are dedicated to pioneering quality products that meet the challenges of customers around the world.

Majestene Bionematicide reduces nematode populations and increases yield and quality in a wide range of specialty and row crops.

MBI entered the water market with Zequanox, the industry’s first bio-based product to selectively control invasive zebra and quagga mussels in pipes and open water.

MBI focuses on bringing effective biological solutions to growers across the full range of their pest management and plant health needs.

MBI has won numerous awards including Agrow Best New Biopesticide for Regalia, Grandevo, Venerate and Majestene and IBMA’s Bernard Blum Award for the microbe behind Venerate, Majestene and MBI-014.

Marrone Bio Innovations, Inc. Given Consensus Recommendation Of “Hold” By Analysts

Shares of Marrone Bio Innovations, Inc. have received an average recommendation of “Hold” from the six research firms that are presently covering the stock, Marketbeat Ratings reports.

Several brokerages have weighed in on MBII. Zacks Investment Research cut Marrone Bio Innovations from a “Hold” rating to a “Sell” rating in a research note on Friday, January 21st. StockNews.com started coverage on Marrone Bio Innovations in a research report on Thursday, March 10th. They set a “Sell” rating for the company.

BlackRock Inc. increased its holdings in Marrone Bio Innovations by 1.5% in the 4th quarter.

Vanguard Group Inc. increased its holdings in Marrone Bio Innovations by 6.2% in the 2nd quarter.

Finally, Uniplan Investment Counsel Inc. increased its holdings in Marrone Bio Innovations by 73.6% in the 3rd quarter.

MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on… and Marrone Bio Innovations wasn’t on the list.

While Marrone Bio Innovations currently has a “Buy” rating among analysts, top-rated analysts believe these five stocks are better buys.