30 Google Trending Breakout Blog Post Ideas – Updated on 2022-04-09

Find trends and resources for the highest search-volume keywords on Google in the last 24 hours below. This post was updated on 2022-04-09.

The automated system gathers resources for each breakout keyword, making it much easier to write blog articles on hot-topics quickly. Use this tool to climb the SEO ladder for free!

Please note that everything on this page is automatically gathered and generated. Skim through blog post ideas until you find something you’re interested in writing about. Take the hard work out of finding and researching popular blog post ideas.

Post Idea #1: Fuel filter

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Fuel Filters

Today’s fuel injector units require cleaner fuel.

High-pressure injectors are less tolerant of both fine solid particles and water that reduce fuel lubricity.

Improved economy and tightened emission standards require increased cylinder combustion pressures, which demand cleaner fuel intake.

Look to NAPA fuel filters for new ways to filter out even the smallest particles of rust, scale, dirt and water that can compromise the life and performance of your engine.

12 Symptoms Of A Clogged Fuel Filter – AutoVfix.Com

Fuel filter is one of that little but very essential piece of your vehicle and that is why in today’s article, we are looking the symptoms of a clogged fuel filter and how to tell if fuel filter is bad. The where fuel filter is located in your car and the cost of fuel filter replacement.

Below are 12 symptoms of a clogged fuel filter and how to tell if fuel filter is bad. Related Articles: How to fix a fuel pump without replacing it |Temporary fuel pump fix.

Although a clogged or immensely dirty fuel filter can cause insufficient fuel supply from reaching the car’s engine.

If the fuel filter goes bad, the pressure of fuel that comes into the system will decrease which will alert the fuel pressure sensor and the Check Engine light will come on.

How To Change Diesel Fuel Filters WHERE FUEL FILTER IS LOCATED. For those who don’t know, the fuel filter is located somewhere in between your fuel tank and your engine.

Normally, the fuel filter is either located inside the fuel tank, or somewhere in the fuel line.

So this is where conclude this article on the 12 symptoms of a clogged fuel filter and how to tell if fuel filter is bad. I help this has helped you please share and bookmark this post for future referencing.

Fuel Filter

A fuel filter is a filter in a fuel line that screens out dirt and rust particles from the fuel, and is normally made into cartridges containing a filter paper.

Fuel filters serve a vital function in today’s modern, tight-tolerance engine fuel systems.

If these substances are not removed before the fuel enters the system, they will cause rapid wear and failure of the fuel pump and injectors, due to the abrasive action of the particles on the high-precision components used in modern injection systems.

This is usually a case of simply disconnecting the filter from the fuel line and replacing it with a new one, although some specially designed filters can be cleaned and reused many times.

If a filter is not replaced regularly it may become clogged with contaminants and cause a restriction in the fuel flow, causing an appreciable drop in engine performance as the engine struggles to draw enough fuel to continue running normally.

It is especially undesirable for water in fuel to be drawn into a diesel engine fuel system, as the system relies on the diesel for lubrication of the moving parts, and if water gets into a moving part which requires constant lubrication, it will quickly cause overheating and unnecessary wear.

In proximity to the diesel fuel filter there might be a fuel heater to avoid the forming of paraffin wax inside the filtrating element which can stop the fuel flow to the engine.

Post Idea #2: Radiological information system

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Radiology Information System

ISSN: 0376-4699.Indian Journal of Chemistry is a leading monthly journal in Organic and Medicinal Chemistry started publishing from 1976.

The Indian Journal of Medical Research is a biomedical journal with international circulation.

Indian Journal of Medical Sciences is a monthly journal published as a medium for the advancement of scientific knowledge in all the branches of medicine and allied sciences and publication of scientific investigation in these fields.

The journal is owned by the Indian Journal of Medical Sciences Trust, a registered charitable organization and published by Medknow Publications, Mumbai, India.

The Journal publishes original scientific research papers, case reports, preliminary articles and information on all aspects of occupational therapy.

The Journal of Biosciences is a quarterly journal published by the Indian Academy of Sciences, Bangalore.

In January 2005, the society released the inaugural issue of its journal, The Journal of the Indian Society of Toxicology.

RIS Imaging Software Services

RIS is a type of radiology software solution for storing and managing medical imaging data.

RIS optimizes the imaging process by integrating the various functions involved in managing patient information into one comprehensive system.

Storing – Stores images obtained from RIS imaging devices and any other relevant patient information on the database.

Image Tracking – RIS enables keeping track of images obtained from medical imaging devices and related patient data.

Collaboration between physicians is facilitated by enabling access to documents to anyone within the computer network when RIS is integrated with a local software solution, or to anyone with internet access when RIS is integrated with a cloud-based solution such as PostDICOM. Patient Management – Significantly facilitates patient management as processes such as patient registration and scheduling are digitized.

When it comes to integration with other medical software, RIS is able to be integrated with and complements HIS and PACS. Medical software systems like RIS and PACS are the contemporary, digital equivalent for paper and film based medical records storage systems.

Learn More about Cloud PACS. Cloud-based PACS Levels the Playing Field for Users of Medical Imaging Information Systems From CIS, HIS, EMR, and EHR, to RIS, DICOM, PACS, and cloud PACS, there are endless terms and abbreviations for the many different types of medical imaging information systems out there.

The Essential Radiology Information System Guide

While there are many exciting technological developments brewing, there’s a core radiology system that changed everything when it was first introduced in the 1960s – the radiology information system.

Perhaps you’re curious about the RIS definition to better understand what the radiology information system purpose is.

Radiology departments use a RIS system to manage scheduling, patient records, results distribution, and much more.

Patient registration and scheduling: A RIS system allows front desk admins to quickly register new patients by inputting information such as their name, sex, birthdate, address, and contact and insurance information within the system.

A well-designed RIS system offers report and document templates to help staff prepare these documents faster without missing key information.

A minor disadvantage of a radiology information system can be that it may take time for your staff to learn and get comfortable with a new RIS. Training sessions, phone calls, or live chats with a vendor for support may be necessary – however, this is the case for just about any new system or software.

In 1980, a group of university and private hospitals created the Radiology Information Systems Consortium to develop requirements for an enhanced RIS and to create a request for proposal for commercial entities to build this system.

Radiological Information System: Benefits And Future In The Healthcare Sector

A Radiological Information System is a networked software system for managing medical imagery and associated data.

The basic features of the Radiological Information System are managing the patient list, result entry, document scanning, digital reporting, and more.

Radiological Information System allows staff to make appointments for patients and other people.

The major feature of the radiological information system is report dissemination.

It is the basic information system across the healthcare system and includes major functions of examination, performance tracking, and procedure billing.

So what are the ways to ensure the relevance of the Radiological Information System in the coming years? Here are a few important points that should be addressed to brighten RIS’s future.

Radiological Information System allows staff to eliminate errors and redundancy found in the patient’s record at the time of registration.

What Is A Radiology Information System In 2022 ?

Because of the nature of the practice, running a successful radiology clinic or department requires a sophisticated database system where medical professionals can keep track of patient data and a high volume of image files.

A Radiology Information System is a sophisticated EHR system designed specifically for use in a radiology practice.

A radiology information system is a networked software system for managing medical imagery and associated data.

RIS Systems provide a portal for Radiology staff to input information more rapidly and with less room for error.

A good RIS system will have a comprehensive billing system that can process electronic payments and automated claims.

As you can see, there is a reason why so many radiology clinics and departments are moving towards the implementation of Radiology Information Systems.

Paper-based systems are out-dated and and a Radiology Information system will get you everything you need to move from a paper-based system to a more secure, efficient and financially beneficial way of managing your radiology practice.

Radiology Information System: A Workflow-Based Approach

Purpose: Introducing workflow management technology in healthcare seems to be prospective in dealing with the problem that the current healthcare Information Systems cannot provide sufficient support for the process management, although several challenges still exist.

The purpose of this paper is to study the method of developing workflow-based information system in radiology department as a use case.

Method: First, a workflow model of typical radiology process was established.

Second, based on the model, the system could be designed and implemented as a group of loosely coupled components.

Each component corresponded to one task in the process and could be assembled by the workflow management system.

Result: The workflow-based Radiology Information System was deployed in the radiology department of Zhejiang Chinese Medicine Hospital in China.

Conclusion: The workflow-based approach is a new method of developing radiology information system with more flexibility, more functionalities of process management and more workflow-aware integration.

Radiology Information System And PACS

The Radiology Information System and Picture Archiving & Communications System facilitates patient care by enabling any person performing imaging procedures.

Relationship with CIS. In a fully integrated system, the requests or orders for radiology examinations are made in the Order Entry application of CIS. It should also be possible to view the status of the progress of the administrative processes, the imaging processes and the radiologist’s reports in CIS. For clinicians to retrieve and view images however, it is sufficient to provide a link to PACS application via a URL. CLIENT-RESOURCE MANAGEMENT SYSTEM IN RIS. In a fully integrated Information System for Patient Care, RIS is built by customizing the.

Imaging equipment need to have a DICOM interface to enable transfer of orders and resultant images from PACS system to them.

The Database Management System for the PACS shall conform to an industry standardThe Contractor shall state the manufacturer and software version of the database used in the PACS.The system shall provide a unified view of and access to all images and related data available in Hospital Selayang irrespective whether the database is central or distributed; allowing for retrieval of any examination known to the system regardless of its physical location.

The Contractor shall ensure that there is one computer, with the necessary accessories to perform image acquisition of radiological images supplied in portable storage media, at each of these locations i.e. the Main Radiology Unit, the Emergency Department radiology Unit and the Outpatient Radiology Unit.

This duplicate system shall be located at a separate location in HS.The PACS system shall have the ability to copy data and images onto suitable portable data storage media for use as back-up during recovery if and when a disaster occurs.

The RIS-PACS system shall allow Radiologists to view, interpret and report on images within either RIS or PACS. Once documented and validated the report shall be displayed in RIS, PACS and at the appropriate location within the patient’s Medical Record.

Post Idea #3: Merge Healthcare

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Post Idea #4: INFINITT Healthcare

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Enterprise Imaging IT Solutions

INFINITT North America is an award-winning developer of imaging IT solutions that empower healthcare providers in the delivery of value-based care.

Learn about INFINITT’s #1 award winning RIS/PACS with the most advanced tools for visualization, analysis, reporting and data management.

Image Management for the academic Dental environment, supporting 2D and 3D imaging and treatment techniques.

INFINITT Healthcare

INFINITT Healthcare Co. Ltd., is a South Korea-based healthcare IT development company.

INFINITT Healthcare specializes in medical imaging and information technology solutions[buzzword.

VNA, and cloud-based software and services.

INFINITT Healthcare started from Mediface, which was the PACS R&D center at Medison and separately founded in 1997.

In 2002, it merged 3DMed and changed its name to INFINITT Technology.

It acquired Marotech and Neobit in 2005 and Mevisys in 2007 and chose its current name “INFINITT Healthcare” in September 2009.

Products and Solutions are provided through these global business units and several other international sales distributors.

INFINITT Healthcare

INFINITT Healthcare Platform is more than just a VNA: Besides the multimedia and rule-based archiving, it also offer information distribution over 27 open interfaces implemented through IHE conform standards such as HL7, FHIR, DICOM, RESTful-DICOM. A deep integration into other PACS and information system is hereby facilitated.

The customer has the choice of leaving non-DICOM data in their original MIME-Type or converting the data into DICOM format.

Different life cycles can be defined for each information category.

Post Idea #5: Real income

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Real Income Definition

Real income is how much money an individual or entity makes after accounting for inflation and is sometimes called real wage when referring to an individual’s income.

Overall, real income is only an estimate of an individual’s purchasing power since the formula for calculating real income uses a broad collection of goods that may or may not closely match the categories an investor spends within.

Analysts of real income can choose any price index measure that they believe best fits their income analysis situation.

BLS Reports The BLS publishes a monthly real earnings report, which can be helpful in keeping tabs on real wage rates.

Individuals looking to calculate their own real wage rate may be better served by adapting the above real income formulas to their own individual situations.

Real Income Formulas For example, a mid-level manager with a nominal $60,000 per year salary might follow the CPI to calculate their real hourly, weekly, monthly, and annual wage rate.

Other takes on the real wage rate might look at the percentage of real to nominal wages or the real vs. nominal wage growth rate.

Meaning, Formula Vs Nominal Income

The Real income of an individual or a country is income adjusted for inflation.

Real income is nominal income adjusted for inflation.

Real income in economics determines purchasing power and financial stability of an individual based on income and inflation.

Real Income vs Nominal Income Real income is adjusted for inflation; it is not the case with nominal income or nominal wage.

Frequently Asked Questions Difference between income and real income? Income is the amount of money an individual or an entity makes.

How does real income affect inflation? When real wage increases, inflation looks small, and purchasing power increases.

Here we explain real income, its formula, examples, and its differences from nominal income.

Real Income Definition & Example

Let’s say John Doe works for Company XYZ. His salary is $100,000 per year.

He started the job five years ago at $100,000 and has not had a raise since he took the job.

Rate is 3% per year, then the value of that $100,000 falls by 3% a year as goods and services get more expensive.

As a result, after the first year on the job, John’s salary is really able to buy only $97,000 of goods and services.

The longer this goes on, the less John’s $100,000 salary buys.

By the end of five years, John’s salary would be ‘worth’ only $85,873.

The concept is at the heart of many labor and salary negotiations.

Definition, Latest News, And Why Real Income Is Important?

Real income is the earnings of individuals or the nation after adjusting to the extent of inflation.

Both the real variables, such as real income and real GDP, must be measured in physical units.

In contrast, nominal variables, such as the nominal income and nominal GDP, will be measured in monetary terms.

Real income is better and a useful indicator of the well-being since it estimates the count of goods and services purchased with the earnings.

If the nominal income continues to be Rs 100 next year, one can buy less to the extent of roughly 9%. Therefore, if nominal income has not been adjusted for inflation every year, the real income has dropped by about 9%. The Formula for Real Income.

There are alternative ways to calculate real income.

Real income analysts can choose any price index indicator they think fits their income analysis situation best.

Real Income Financial Definition Of Real Income

Real incomeThe income of an individual, group, or country adjusted for inflation.

Real IncomePersonal, corporate, or national income after accounting for inflation.

Comparing one’s real income from year to year shows how much income has grown or shrunk after adjusting for how much the buying power of the money has been affected.

If one’s nominal income has grown 10% and the inflation rate is 3%, the real income growth is 7%. Real income is also known as real wages.

Real income measures purchasing power in the current year after an adjustment for changes in prices since a selected base year.

If money income increases more than consumer prices, real income increases.

If money income increases less than consumer prices, real income declines.

Real Earnings Summary

Gov REAL EARNINGS JANUARY 2022 All employees Real average hourly earnings for all employees increased 0.1 percent from December to January, seasonally adjusted, the U.S. Bureau of Labor Statistics reported today.

Real average weekly earnings decreased 0.5 percent over the month due to the change in real average hourly earnings combined with a decrease of 0.6 percent in the average workweek.

Real average hourly earnings decreased 1.7 percent, seasonally adjusted, from January 2021 to January 2022.

The change in real average hourly earnings combined with a decrease of 1.4 percent in the average workweek resulted in a 3.1-percent decrease in real average weekly earnings over this period.

Real average weekly earnings decreased 0.6 percent over the month due to the unchanged real average hourly earnings being combined with a decrease of 0.6 percent in average weekly hours.

The change in real average hourly earnings combined with a decrease of 1.5 percent in the average workweek resulted in a 2.7-percent decrease in real average weekly earnings over this period.

Revisions to Real Earnings Data * * * * The seasonally adjusted constant dollar series have been revised to reflect new seasonal adjustment * * factors calculated for the CPI-U and CPI-W. This revision affects real earnings for both all * * employees and production and nonsupervisory employees from January 2017 through December 2021.

23 Passive Income Ideas To Build Wealth In 2022

This article breaks down 23 ideas for how to generate passive income while keeping your full-time gig.

Active Income vs. Passive Income – Which Is Best for Me? In theory, all of your income sources carry similar weight.

Making passive income comparable to income earned from active efforts requires a good amount of work upfront.

We might only be on the sixth passive income idea on this list, but you probably noticed a trend: Creating stuff tends to lead to passive income.

What passive income ideas can I start with little money?

If you’re looking to replace your 9 to 5 income so you can quit your job, the passive income ideas on this list can help you do that.

Which of these passive income ideas will you be trying out today? Comment below!

Post Idea #6: Energy conservation

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Energy Conservation: Benefits, Ways To Conserve, Importance

While there are different types of energy, the only types of energy we can save are electrical energy and thermal energy.

Energy can be conserved by using energy-efficient devices and other methods to consume energy and reduce the use of energy when there is no requirement.

Energy conservation act, 2021 promotes the efficient use of energy and its conservation.

The primary method to conserve energy is to use clean and alternative sources of energy like wind energy, solar energy, tidal energy, and biomass energy.

What is the law of conservation of energy?Ans: The law of conservation of energy states that the total energy of an isolated system remains constant.

What are the benefits of energy conservation?Ans: Energy conservation reduces the expense of energy utilization.

Why is energy conservation day celebrated?Ans: Energy conservation day promotes the thought of conserving energy, and it provides awareness among public about the adverse effect of greenhouse gases.

Energy Conservation Guide: How To Save Energy & Nature

Our energy conservation guide will highlight everything you should know about saving and conserving energy.

In simple words, energy conservation means reducing energy consumption.

Under the umbrella term of energy consumption comes energy efficiency, renewable energy, and wastage reduction.

Are energy conservation and energy efficiency the same thing?

Did you know you can save money on energy without installing anything? You can use Arcadia Power to move to clean energy.

Aside from the energy conservation examples above, you can hire an energy audit company or expert to audit your house and recommend measures to make it more efficient.

Like all these tips mentioned above? Use these other energy conservation methods to reduce consumption and save money along the way.

Energy Conservation What is Energy Conservation? After being in the hospital, it is normal to feel tired and weak.

Learning how to conserve your energy helps you build up your strength to take part in your daily activities and other things you enjoy doing.

Learning to conserve your energy is all about finding a good balance between work, rest and leisure in order to decrease the amount of energy demand on your body.

Sitting supports your body so you can focus on your breathing and activities while conserving your energy.

Sitting reduces energy use by 25%. Energy Conservation Tips Dressing and Hygiene Sit when you can.

Use electric appliances such as can openers, blenders, food processors and dishwasher to conserve energy.

Use assistive devices when recommended to save energy and make it more comfortable and easy taking care of yourself.

Energy Conservation

Energy conservation is the effort made to reduce the consumption of energy by using less of an energy service.

An energy audit is an inspection and analysis of energy use and flows for energy conservation in a building, process, or system with an eye toward reducing energy input without negatively affecting output.

Energy conservation measures are often combined into larger guaranteed Energy Savings Performance Contracts to maximize energy savings while minimizing disruption to building occupants by coordinating renovations.

In Lebanon and since 2002 The Lebanese Center for Energy Conservation has been promoting the development of efficient and rational uses of energy and the use of renewable energy at the consumer level.

Due to the lack of a government organization that promotes energy efficiency in the country, the Federation of Nepalese Chambers of Commerce and Industry has established the Energy Efficiency Centre under his roof to promote energy conservation in the private sector.

In New Zealand the Energy Efficiency and Conservation Authority is the Government Agency responsible for promoting energy efficiency and conservation.

The Sri Lanka Sustainable Energy Authority is playing a major role regarding energy management and energy conservation.

U.S. Energy Information Administration

Energy efficiency and energy conservation are related and often complimentary or overlapping ways to avoid or reduce energy consumption.

Energy efficiency generally pertains to the technical performance of energy conversion and consuming devices and building materials.

Energy conservation generally includes actions to reduce the amount of energy end use.

EE and EC measures can help to directly lower energy costs for consumers and potentially reduce greenhouse gas emissions associated with energy use.

Many electric utilities offer EE and EC programs to their customers in part because of state energy efficiency resource standards, which set mandatory, long-term targets for reducing energy use, and/or as required by state utility regulatory agencies as part of investor-owned utility resource planning.

According to the U.S. Energy Information Administration’s annual survey of electric power sales, revenue, and energy efficiency, in 2020, 502 electric utilities had EE programs that resulted in an estimated 28,167,459 megawatthours reductions in total annual electricity consumption.

Residential customers accounted for about 47% of the total annual electricity savings from utility EE programs and commercial customers accounted for 44% of the energy efficiency savings in 2020.

Principle Of Conservation Of Energy, Derivation, Energy Conservation, Examples, And FAQs

What is the Law of Conservation of Energy? The law of conservation of energy states that energy can neither be created nor be destroyed.

Law of Conservation of Energy Derivation Considering the potential energy at the surface of the earth to be zero.

E = mg(H – X) + mgX. E = mg(H – X + X). E = mgH. Similarly, if we see the energy at point C, which is at the bottom of the tree, it will come out to be mgH. We can see as the fruit is falling to the bottom and here, potential energy is getting converted into kinetic energy.

Energy Conservation: Energy conservation is not about limiting the use of resources which will finally run out altogether.

Law of Conservation of Energy Examples: In Physics, most of the inventions rely on the fact that energy is conserved when it is transferred from one form to another.

The potential energy of water is converted into the kinetic energy of the turbine, which is further converted into electrical energy.

Frequently Asked Questions – FAQs.What is energy?State the law of conservation of energy?Which types of energy can be seen when a block slides down a slope?Give an example where potential energy is converted into kinetic energy?Give an example to prove energy is conserved?

Energy Conservation: 15 Ways To Save Energy

There are many different ways to save energy at home and increase energy savings, ranging from simple behavioral adjustments to extensive home improvements.

At its core, energy conservation is the practice of using less energy in order to lower costs and reduce environmental impact.

With finite energy resources available on our planet, actively conserving energy when possible is beneficial individually and to our larger energy systems.

To reduce energy consumption in your home and increase your energy savings, you do not necessarily need to go out and purchase energy efficient products.

When purchasing an energy efficient appliance, you should look for appliances with the ENERGY STAR label, which is a federal guarantee that the appliance will consume less energy during use and when on standby than standard models.

ENERGY STAR certified clothes washers consume 25% less energy and 45% less water than conventional ones, whereas ENERGY STAR refrigerators use only 9% less energy.

ENERGY STAR furnaces in the northern half of the U.S. are labeled with the standard ENERGY STAR logo and are up to 16% more energy efficient than baseline models.

Post Idea #7: Mobile virtual network operator

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MVNO stands for “Mobile Virtual Network Operator,” and being virtual, that means an MVNO does not own the wireless network towers that it uses.

A typical larger sized MVNO buys wholesale minutes, data, and text from a major wireless carrier, and sometimes multiple or all of the major carriers, and then resells the talk, text, and data to you under their own brand name.

In either case, and in the simplest of terms possible, an MVNO means a third-party provider that grants its customers access to one of the Big 3 carrier networks.

There are many reasons why a carrier may want to have MVNO partners.

The following table lists the known number of MVNO and carrier prepaid brand subscribers from various wireless brands that have publicly stated them at one time or another.

If you are interested in finding out more about MVNOs and finding one that can help save you money, you may want to start by exploring the MVNO list down below or by using the BestMVNO wireless phone plan comparison tool.

This MVNO list contains all the major wireless providers and resellers in the USA. Subscribing to the right MVNO can save you a lot of money on your phone bill.

What Is A Mobile Virtual Network Operator?

Mobile virtual network operators or MVNOs play a unique part in today’s economy.

A mobile virtual network operator or MVNO is a wireless communications service provider.

Unlike traditional mobile network operators, MVNOs do not own the infrastructure they use.

Tesco Mobile is an MVNO. It offers cell phones, call plans, and data as an MVNO. Tesco Mobile is able to be an MVNO by leveraging O2’s mobile network infrastructure.

MVNOs don’t invest in mobile network infrastructure but must provide other important services that support their clients.

Mobile operators choose to leverage MVNOs for two main reasons.

Full MVNO. Full MVNO is considered the most entrenched type of MVNO. Full-MVNOs typically have greater access to the mobile network operator’s infrastructure.

Mobile Virtual Network Operator

An MVNO enters into a business agreement with a mobile network operator to obtain bulk access to network services at wholesale rates, then sets retail prices independently.

An MVNO may use its own customer service, billing support systems, marketing, and sales personnel, or it could employ the services of a mobile virtual network enabler.

MVNO agreements with network operators date back to the 1990s, when the European telecom market saw market liberalization, new regulatory frameworks, better 2G network technology, and a subsequent jump in wireless subscriber numbers.

Because MVNOs are effectively defined by their lack of spectrum licenses, an MVNO necessarily will need to have agreements in place to access the network of at least one MNO. The type of MVNO is determined by how “Thick” or “Thin” a technological layer an MVNO adds over its access to its host MNO’s network.

Full MVNO. These MVNOs have a network implementation operating essentially the same technology as a mobile network operator.

As of December 2018, there were 1,300 active MVNOs operating in 79 countries, representing more than 220 million mobile connections – or approximately 2.46% of the total 8.9 billion mobile connections in the world.

The MVNOs combined market share was 15.9% of the total UK mobile market, representing 15.3 million connections; that is, 23 out of every 100 subscribers having their mobile phone service with an MVNO. [edit].

Mobile Virtual Network Operators Explained

Mobile virtual network operators are wireless carriers that do not operate their own network hardware.

Rather than operate a network, MVNOs generally pay wholesale rates to operate over another company’s network.

The network used by an MVNO is sometimes referred to as the MVNO’s “Host operator.” A list of U.S. MVNOs can be found here.

When networks are under heavy loads, network access for MVNO subscribers may be prioritized lower than direct subscribers’ access to the host operator.

At a crowded, outdoor festival, T-Mobile’s network might be under an unusual load. In this case, T-Mobile’s direct subscribers may have higher download speeds than those using T-Mobile-based MVNOs.

Some MVNOs have direct partnerships with network operators; others work through middle-man companies that handle some of the logistics involved in reselling access to a host operator’s network.

1 Some MVNOs will offer services from only one network.

Mobile Virtual Network Operator Market Revenue Growth, Key Players, Qualitative & Quantitative Analysis 2030

The latest uploaded report titled Mobile Virtual Network Operator Market: By Size, Share, Growth, Segments, Analysis and Forecast, 2030 by one of the leading market research firms provides an industry overview, clarifying the market definition and specifications of the market.

The whole dashboard read of the Mobile Virtual Network Operator Market offered by this report will help the readers to look at in-depth data regarding the market.

An assessment of market effect factors and their impact on the forecast and outlook of the Mobile Virtual Network Operator Market has also been given.

The study isolates the Mobile Virtual Network Operator Market based on the key players, type, application, and regions.

Finally, the report sheds light on the sustainable trends and platforms that are the basis for Mobile Virtual Network Operator Market growth.

The dominating players are adopting new strategies and looking for new funding resources to overcome the rising obstacles in the Mobile Virtual Network Operator Market growth due to the pandemic.

Who are the global key players in this Mobile Virtual Network Operator Market?

Mobile Virtual Network Operator Market Size, Development, Key Opportunity 2022-2027

Report on Mobile Virtual Network Operator Market explores the essential factors of Mobile Virtual Network Operator industry covering current scenario, market demand information, coverage of active companies and segmentation forecasts.

In the present scenario, competition in the Mobile Virtual Network Operator market has transferred from pricing to value-added services and product variation, due to the importance of mobile network operators has grown exponentially in the low-cost cellular services market across developed and emerging nations.

The report Mobile Virtual Network Operator Market Size and Analysis maintains enhanced dynamics and is overshadowed by a top player across the globe.

The research report provides Mobile Virtual Network Operator Market Growth and information corresponding to market segments such as geographies, product type, application, and end-use industry.

For the historical and forecast period 2015 to 2025, it provides detailed and accurate country-wise volume analysis and region-wise market size analysis of the global Mobile Virtual Network Operator Market.

Investigation and analysis of the Mobile Virtual Network Operator Market according to key regions / countries, product type and application, historical data and forecast to 2027.

Projecting the size of Mobile Virtual Network Operator Market’s sub-markets in relation to key regions.

What Is An MVNO?

MVNO stands for mobile virtual network operator, which means that MVNOs use one or several major networks to provide you with cell phone service.

The low price of these MVNO phone plans makes them an attractive option if you’re looking to save on your monthly spending.

MVNOs offer a wide variety of phone plans, with many small carriers even allowing you to build your own plan.

Although most MVNOs don’t offer as many plan perks as the majors, they make up for it by often running deals or specials on their plans, making MVNOs an even more appealing option for budget-minded customers.

The majority of MVNOs sell a nice selection of smartphones, although many of these MVNOs partner with third-party financing companies, such as Affirm or SmartPay, to provide customers with a monthly installment plan.

If you know which network you want your cell phone plan on, then you’ll need to know which network each MVNO uses.

If you’re searching for an affordable family plan, you have no shortage of options-almost every MVNO offers family plans.

Post Idea #8: Head louse

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Head Louse

Louse infestation of the body is known as pediculosis, pediculosis capitis for head lice, pediculosis corporis for body lice, and phthiriasis for pubic lice.

Unlike body lice, head lice are not the vectors of any known diseases, however rare secondary infections can result from scratching at bites.

Head louse infestations may be beneficial in helping to foster a natural immune response against lice which helps humans in defense against the far more dangerous body louse, which is capable of transmitting dangerous diseases.

One pair of antennae, each with five segments, protrudes from the insect’s head. Head lice also have one pair of eyes.

Head lice eggs are brown or white and attached to the hair.

Head lice reproduce sexually, and copulation is necessary for the female to produce fertile eggs.

Normally, head lice infest a new host only by close contact between individuals, making social contacts among children and parent-child interactions more likely routes of infestation than shared combs, hats, brushes, towels, clothing, beds, or closets.

Symptoms And Causes

Head lice are tiny insects that feed on blood from the human scalp.

An infestation of head lice most often affects children and usually results from the direct transfer of lice from the hair of one person to the hair of another.

Household pets, such as dogs and cats, don’t play a role in spreading head lice.

Because head lice are spread primarily by direct head-to-head contact, the risk of transmission is greatest among younger people who play or go to school together.

In the United States, cases of head lice most often occur in children in preschool through elementary school.

It’s difficult to prevent the spread of head lice among children in child care facilities and schools because there is so much close contact.

Not lie on beds, couches or pillows that have been in contact with a person infested by head lice.

ScienceDirect Topics

Juvenile lice hatch after a couple of days and develop to adult lice within 3.

No head lice were observed on the floor and the furniture of 118 Australian classrooms, although the 2230 pupils of the schools had altogether 14 003 lice on their heads.

Although human immunodeficiency virus has been demonstrated in lice, no epidemiologic link yet exists between lice and HIV transmission.

Habitat ModificationHead lice and pubic lice may be completely eliminated by shaving the affected area.

Essential oils are an attractive alternative and, over the last 10 years, many essential oils and their components have been tested against head lice and found to be effective.

GlaxoSmithKline conducted a study in 2006 and found that-terpinen-4-ol was the most effective compound against adult lice, whereas nerolidol was particularly lethal to eggs, but ineffective against adult lice.

Most lice infestations are asymptomatic; some children can harbor a surprisingly large colony of head lice.

Each louse has six legs and each leg contains its own claws! Ouch!The head louse makes itself at home on the human scalp, eyebrows, and eyelashes, which is where you’ll find this annoying parasite.

An estimated six million or more children are infested each year in the United States alone.

While nestled close to the scalp, the louse feeds every few hours on a steady supply of human blood.

Head lice do not spread diseases, but they can cause itching and other mild symptoms and often must be treated with medication.

Each louse has six legs and each leg contains its own claws! Ouch!

Head lice often spread from person to person by direct head-to-head contact, though they can be transmitted through clothing, brushes, beds, or other items that have been in contact with an infested person.

With a constant supply of nourishing blood, adult head lice can live on a person’s head for up to a month!

Head Lice Treatment, Symptoms, Infestation Causes, Pictures, Remedies

5%: Malathion is an organophosphate insecticide that is only available as a prescription and it kills live lice and the lice inside the eggs/nits.

It has actually been pulled off the market twice due to safety concerns, but it was reintroduced in the United States in 1999 due to increasing resistance of head lice to other treatments.

It is not ovicidal and needs to be repeated in one week if there is any evidence of live lice.

Topical ivermectin lotion may be used in the treatment of lice in children 6 months of age and older.

While oral invermectin is commonly used in other countries for lice, it is currently not approved for the treatment of head lice in the U.S. In countries where it is approved, the dosage is usually a single dose, which is often repeated in nine days.

Lindane: It is important to note that lindane 1% is no longer recommended as a treatment option for head lice due to its toxicity in children.

Other treatments such as permethrin 5%, crotamiton 10%, and sulfamethoxazole-trimethoprim are not currently approved by the FDA for the use in the treatment of head lice.

Head Lice

Pediculus humanus capitis, the head louse, is an insect of the order Psocodea and is an ectoparasite whose only host are humans.

The life cycle of the head louse has three stages: egg, nymph, and adult.

Nits are laid by the adult female and are cemented at the base of the hair shaft nearest the scalp.

The nymph looks like an adult head louse, but is about the size of a pinhead. Nymphs mature after three molts and become adults about 7 days after hatching.

Adults: The adult louse is about the size of a sesame seed, has 6 legs, and is tan to grayish-white.

In persons with dark hair, the adult louse will appear darker.

Adult lice can live up to 30 days on a person’s head. To live, adult lice need to feed on blood several times daily.

What Do Lice Look Like? Pictures Of Nits, Eggs, And Lice

Nits are small, oval-shaped, usually a yellowish-white color, and are firmly attached to the side of hair shafts.

Simply having nits does not necessarily mean that your child has live lice since some nits may be empty egg casings and some may have dead, non-infective lice embryos inside.

Nits that are close to your child’s scalp are the ones that are most likely to be infective and are the ones that are thought to hatch into live lice, a process that takes six to nine days.

Continuing to get new nits even after you have removed nits from your child’s hair is also a likely sign that your child has live lice and needs a lice treatment.

A live louse will typically lay up to eight eggs a day, so if your child only has a few nits, they likely don’t have an active lice infestation.

To add to the confusion about head lice, some people only use the term nits to refer to empty egg casings and lice eggs when talking about viable eggs.

Others use the term nits to refer to both viable lice eggs and empty egg casings.

Post Idea #9: Head lice infestation

Related Articles – Summarized

Symptoms And Causes

Head lice are tiny insects that feed on blood from the human scalp.

An infestation of head lice most often affects children and usually results from the direct transfer of lice from the hair of one person to the hair of another.

Household pets, such as dogs and cats, don’t play a role in spreading head lice.

Because head lice are spread primarily by direct head-to-head contact, the risk of transmission is greatest among younger people who play or go to school together.

In the United States, cases of head lice most often occur in children in preschool through elementary school.

It’s difficult to prevent the spread of head lice among children in child care facilities and schools because there is so much close contact.

Not lie on beds, couches or pillows that have been in contact with a person infested by head lice.

Head Lice

Head lice infest the head and neck and attach their eggs to the base of the hair shaft.

Head lice infestation, or pediculosis, is spread most commonly by close person-to-person contact.

Dogs, cats, and other pets do not play a role in the transmission of human lice.

Both over-the-counter and prescription medications are available for treatment of head lice infestations.

Images: Two lice viewed under an electron microscope.

Head Lice Infestation: Causes, Symptoms & Diagnosis

Touching your head to the head of someone with head lice.

Running a fine-toothed lice comb through your hair, starting from the scalp, to catch lice and nits.

You’ll most likely find nits if you find any evidence of head lice on your scalp.

Some of the major treatments for head lice are described below.

Two types of chemicals are commonly used in OTC head lice treatment.

It’s used to treat head lice in people 6 months old and older.

If you want to avoid using pesticides, use a fine-toothed lice comb or a flea comb to remove lice.

Treating And Preventing Head Lice

Head lice are most common among preschool children attending child care, elementary school children, and household members of children who have head lice.

You cannot get head lice from your pets; lice feed only on humans.

Head lice are most common among preschool children attending child care, elementary school children, and household members of children who have lice.

Another option available are lice removal kits, which are a comb or comb-like device intended to remove and/or kill lice and nits.

After finishing treatment with lice medication, check everyone in your family for lice after one week.

A lice removal kit may be used alone to remove and/or kill head lice and nits.

After rinsing the product from the hair and scalp, use a fine-toothed comb or a lice removal kit to remove dead lice and nits.

Head Lice Treatment, Symptoms, Infestation Causes, Pictures, Remedies

5%: Malathion is an organophosphate insecticide that is only available as a prescription and it kills live lice and the lice inside the eggs/nits.

It has actually been pulled off the market twice due to safety concerns, but it was reintroduced in the United States in 1999 due to increasing resistance of head lice to other treatments.

It is not ovicidal and needs to be repeated in one week if there is any evidence of live lice.

Topical ivermectin lotion may be used in the treatment of lice in children 6 months of age and older.

While oral invermectin is commonly used in other countries for lice, it is currently not approved for the treatment of head lice in the U.S. In countries where it is approved, the dosage is usually a single dose, which is often repeated in nine days.

Lindane: It is important to note that lindane 1% is no longer recommended as a treatment option for head lice due to its toxicity in children.

Other treatments such as permethrin 5%, crotamiton 10%, and sulfamethoxazole-trimethoprim are not currently approved by the FDA for the use in the treatment of head lice.

Head Lice Infestation: What To Do In Extreme Cases

More often than not, head lice aren’t really a serious problem.

In this case, the head becomes crowded with full-grown lice and their nits, and a simple treatment won’t cut it.

In the case of an extreme lice infestation, there’s one thing you must do immediately: Seek professional help.

In an extreme case, the experts may even recommend shaving the head, then using a follow-up treatment to eradicate the lice for good.

This is the most important thing to remember: All head lice cases should be treated immediately.

Lice Lifters Treatment Centers will handle your head lice problem for children or adults, no matter how simple or severe.

To schedule an emergency removal appointment or consult with a lice technician, call Lice Lifters Treatment Centers today at 972-805-1308.

What Do Lice Look Like? Pictures Of Nits, Eggs, And Lice

Nits are small, oval-shaped, usually a yellowish-white color, and are firmly attached to the side of hair shafts.

Simply having nits does not necessarily mean that your child has live lice since some nits may be empty egg casings and some may have dead, non-infective lice embryos inside.

Nits that are close to your child’s scalp are the ones that are most likely to be infective and are the ones that are thought to hatch into live lice, a process that takes six to nine days.

Continuing to get new nits even after you have removed nits from your child’s hair is also a likely sign that your child has live lice and needs a lice treatment.

A live louse will typically lay up to eight eggs a day, so if your child only has a few nits, they likely don’t have an active lice infestation.

To add to the confusion about head lice, some people only use the term nits to refer to empty egg casings and lice eggs when talking about viable eggs.

Others use the term nits to refer to both viable lice eggs and empty egg casings.

Post Idea #10: Scientific modelling

Related Articles – Summarized

Scientific Modelling

A scientific model seeks to represent empirical objects, phenomena, and physical processes in a logical and objective way.

Complete and true representation may be impossible, but scientific debate often concerns which is the better model for a given task, e.g., which is the more accurate climate model for seasonal forecasting.

Modelling is the process of generating a model as a conceptual representation of some phenomenon.

Such differences may be due to differing requirements of the model’s end users, or to conceptual or aesthetic differences among the modelers and to contingent decisions made during the modelling process.

Assumptions are used in modelling in order to specify the domain of application of the model.

Space mapping refers to a methodology that employs a “Quasi-global” modelling formulation to link companion “Coarse” with “Fine” models of different complexities.

Model based learning includes cognitive reasoning skills where existing models can be improved upon by the construction of newer models using the old models as a basis.

Scientific Modeling

Scientific models are used to explain and predict the behaviour of real objects or systems and are used in a variety of scientific disciplines, ranging from physics and chemistry to ecology and the Earth sciences.

Although modeling is a central component of modern science, scientific models at best are approximations of the objects and systems that they represent-they are not exact replicas.

Such as the three-dimensional double-helix model of DNA, are used primarily to visualize an object or system, often being created from experimental data.

Because no single predictive model can account for all the variables that may affect an outcome, scientists must make assumptions, which can compromise the reliability of a predictive model and lead to incorrect conclusions.

The limitations of scientific modeling are emphasized by the fact that models generally are not complete representations.

In the attempt to fully understand an object or system, multiple models, each representing a part of the object or system, are needed.

In the latter case, one model of note is the general circulation model, which is used for simulating human- and non-human-induced climate change.

Scientific Modelling

Models have a variety of uses – from providing a way of explaining complex data to presenting as a hypothesis.

There may be more than one model proposed by scientists to explain or predict what might happen in particular circumstances.

Often scientists will argue about the ‘rightness’ of their model, and in the process, the model will evolve or be rejected.

Models further rely on the work of scientists to collect quality data to feed into the models.

To learn more about work to collate data for models, look at the Argo Project and the work being done to collect large-scale temperature and salinity data to understand what role the ocean plays in climate and climate change.

Models need to be continually tested to see if the data used provides useful information.

A question scientists can ask of a model is: Does it fit the data that we know?

Modeling In Scientific Research

Not all models used in scientific research are physical models.

Whether developing a conceptual model like the atomic model, a physical model like a miniature river delta, or a computer model like a global climate model, the first step is to define the system that is to be modeled and the goals for the model.

While conceptual and physical models have long been a component of all scientific disciplines, computer-based modeling is a more recent development, and one that is frequently misunderstood.

Modeling in practice: The development of global climate models.

The widespread use of modeling has also led to widespread misconceptions about models, particularly with respect to their ability to predict.

Modeling has also moved out of the realm of science into recreation, and many computer games like SimCity® involve both conceptual modeling and computer modeling, using the same kinds of equations that are used model traffic flow patterns in real cities.

Scientific modeling is a research method scientists use to replicate real-world systems – whether it’s a conceptual model of an atom, a physical model of a river delta, or a computer model of global climate.

Scientific Modelling Is Steering Our Response To Coronavirus. But What Is Scientific Modelling?

Many people don’t have a clear understanding of what scientific models are, and what we can and can’t expect from them.

Scientific models can be powerful tools for understanding complex phenomena such as pandemics, but they can’t tell us everything.

Scientific models are representations of parts of the real world.

Scientific models let us explore features of the real world that we can’t investigate directly.

The lack of extensive local data has left our policymakers relying on models based on a combination of overseas data, general theory and pre-existing modelling of influenza pandemics.

As we build a more detailed picture of Australian circumstances, modelling will become more specific and more accurate, and these general models will be less important.

One challenge for modelling in a real-world context like COVID-19 is that our models may not get it right every time.

Models In Science

Standard examples of models of this kind are scale models of objects like bridges and ships, Watson and Crick’s metal model of DNA, Phillips and Newlyn’s hydraulic model of an economy, the US Army Corps of Engineers’ model of the San Francisco Bay, Kendrew’s plasticine model of myoglobin, and model organisms in the life sciences.

One pervasive criticism is that many types of models that play an important role in science are not structures and cannot be accommodated within the structuralist view of models, which can neither account for how these models are constructed nor for how they work in the context of investigation.

How can they fulfill this function given that they typically involve idealizations? Do these models explain despite or because of the idealizations they involve? Does an explanatory use of models presuppose that they represent, or can non-representational models also explain? And what kind of explanation do models provide?

As Hesse points out, many models in science are both logical and representational models.

Bailer-Jones interviewed a group of physicists about their understanding of models and their relation to theories, and reports widely diverging views: there is no substantive difference between model and theory; models become theories when their degree of confirmation increases; models contain simplifications and omissions, while theories are accurate and complete; theories are more general than models, and modeling is about applying general theories to specific cases.

The fourth view seems closely aligned with interpretative models and the idea that models are mediators, but being more general is a gradual notion and hence does not provide a clear-cut criterion to distinguish between theories and models.

What role do general laws play in science if it is models that represent what is happening in the world? And how are models and laws related?

Science Modeling Documents

With Science Modeling Now Co., LLC, you have everything you need to keep your projects on schedule.

We provide a variety of science modeling documents in Detroit, MI. Our documents allow clients in many sectors to get the most from their systems.

We offer a variety of topic modeling resources in general multiple variables.

We utilize cutting-edge methods and accurate scientific modeling to depict the behavior of various systems.

A graduate of Wayne State University, Edward began publishing science models in 2002.

He has devoted his time to creating multiple variables-dependent modeling and optimization systems.

Contact us to learn more about our modeling documents for biological research and mathematical studies.

Post Idea #11: TCL Technology

Related Articles – Summarized

TCL Support

ALERT: Software updates for TCL Television Models featuring Google TV.TCL is committed to delivering premium products with world-class experiences and the new product featuring Google TV is certainly no different.

Recent software updates have allowed us to make significant improvements on the stability and speed of the TCL televisions featuring Google TV. With these updates, this product now represents the powerful performance that TCL and Google believe is the future of TV.Your TCL model with Google TV will update automatically.

If you are having problems, we encourage you to ensure you have the most recent software by clicking here to view step-by-step instructions on how to easily perform an update.

TCL Technology

TCL Technology is a Chinese electronics company headquartered in Huizhou, Guangdong Province.

In July 2003, TCL chairman Li Dongsheng formally announced a “Dragon and Tiger Plan” to establish two competitive TCL businesses in global markets and three leading businesses inside China.

TCL took a 67 percent stake in the joint venture, with Thomson SA holding the rest of the shares, and it was agreed that televisions made by TCL-Thomson would be marketed under the TCL brand in Asia and the Thomson and RCA brands in Europe and North America.

In June 2007, TCL announced that its mobile phone division planned to cease using the Alcatel brand and switch entirely to the TCL brand within five years.

In 2019, due to restructuring, TCL completed the handover of major assets and was split into TCL Technology Group Corporation and TCL Industrial Holdings.

TCL Corporation also has its own research facility called TCL Corporate Research, which is located in Shenzhen, with the objective to research cutting-edge technology innovations for other subsidiaries.

In late 2019, TCL released their first own-branded Android phone, called the TCL Plex.

TCL Communication

TCL Communication Technology Holdings Limited with its North America headquarters based in Irvine, California, is a wholly owned company of TCL Corporation, a global consumer electronics brand with products currently sold in over 160 countries.

With a mobile handset product portfolio that includes devices from TCL, Alcatel and BlackBerry, TCT is currently the fourth largest handset manufacturer in North America.

The company also operates nine R&D centers worldwide and employs over 13,500 people globally.

Tcl Technology

Ad save on tcl 4 series, 5 series, 6 series smart led tv & accessories.

Tcl delivers meaningful experiences through thoughtful design and the latest technology, helping you enjoy more of the things you love.

Founded over 35 years ago, tcl prides itself on delivering more to consumers with high quality products featuring stylish design and the latest technology.

Tcl supports multiple programming paradigms, including object.

Tcl technology group corporation, azienda multinazionale con sede a shenzhen, nel guandong, opera nei settori industriale e finanziario attraverso le sue controllate.

For any service enquiries and support for tcl products, you can contact us on our customer service hotline no.

Tcl 30 v 5g is priced at $299, with its north america headquarters based in irvine, california, is a wholly owned company of tcl corporation, a global consumer electronics brand with products currently sold in over 160 countries.

Tcl Technology

Tcl-Technology explore all that tech that changes our life from the high-tech city to the deepest forest in the world.

Its find how the biggest invention of time changes the life the world also it show how small invention or the old tech helps small group of people live their life happily.

We talks about the new technology from agriculture technology, space technology, environment, computer, mobile technology and may other technology our main focus is to share the tech that other people don’t post often.

We also post popular techs and the evens all around the world.

Anyone can be a part of this blog just yo have to apply us through contact from.

Technical College Of The Lowcountry

Home – Technical College of the Lowcountry Step Up with TCL TCL offers a rewarding college experience close to home at a price you can afford.

Student-centered learning happens in real-world settings in and out of the classroom, in-person and online.

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Post Idea #12: Television set

Related Articles – Summarized

The Best TVs For 2022

Which TV should you buy? Here are the main points to consider when shopping for a new set, as well as the best TVs we’ve tested.

Apple AirPlay 2 has been added to several new TVs from LG, Samsung, Sony, and Vizio, along with all Roku media streamers including Roku TVs. This lets you use your iPhone or iPad to stream content from iTunes to the TV. Apple also has the Apple TV app with its Apple TV+ service on all major smart TV platforms, so you can watch Apple video content on nearly any TV without needing an Apple TV 4K, which was previously necessary.

New TVs don’t usually hit shelves until spring or summer, so you’re looking at a solid three or four months where you know what new TVs are coming out.

LED TVs simply backlight the LCDs with LEDs, while LCD TVs use CCFL for backlighting.

For more, see our stories on how to choose the right TV screen size, the best 65-Inch TVs, and the best 75-Inch TVs.TV Refresh Rate and Contrast Ratio.

Ignore any claims of contrast ratios in the millions or infinity; with the exception of OLEDs, the best TVs tend to have just five-digit contrast ratios.

The Best Outdoor TVs. As a rule, TVs aren’t rugged and you shouldn’t use them outside.

Television Set Crossword Clue

Search millions of clues to find answers to crossword puzzle clues.

Wordplays has answers to Quick puzzles, General Knowledge puzzles, Cryptic Crossword Puzzles, and Variety puzzles.

The Crossword Solver find answers to clues found in the New York Times Crossword, USA Today Crossword, LA Times Crossword, Daily Celebrity Crossword, The Guardian, the Daily Mirror, Coffee Break puzzles, Telegraph crosswords and many other popular crossword puzzles.

Television Set

A television set or television receiver, more commonly called the television, TV, TV set, tube, telly, or tele, is a device that combines a tuner, display, and loudspeakers, for the purpose of viewing and hearing television broadcasts, or using it as a computer monitor.

The addition of color to broadcast television after 1953 further increased the popularity of television sets in the 1960s, and an outdoor antenna became a common feature of suburban homes.

The ubiquitous television set became the display device for the first recorded media in the 1970s, such as Betamax, VHS and later DVD. It has been used as a display device since the first generation of home computers and dedicated video game consoles in the 1980s.

Television usage in the western world skyrocketed after World War II with the lifting of the manufacturing freeze, war-related technological advances, the drop in television prices caused by mass production, increased leisure time, and additional disposable income.

The first fully transistorized, portable solid-state television set was the 8-inch Sony TV8-301, developed in 1959 and released in 1960.

In 1936, for a tube capable of being mounted horizontally in the television cabinet, nine inches would have been regarded as the largest convenient size that could be made owing to its required length, due to the low deflection angles of CRTs produced in the era, which meant that CRTs with large front sizes would have also needed to be very deep, which caused such CRTs to be installed at an angle to reduce the cabinet depth of the TV set.

Due to recent changes in electronic waste legislation, economical and environmentally friendly television disposal has been made increasingly more available in the form of television recycling.

Post Idea #13: Samsung Electronics

Related Articles – Summarized

Home Electronics

Buy one, save 20%. Buy two, save 25%. Buy three, save 30%. For a limited time.

Shop for one Buy more, save more Buy now and get up to $100 instant Samsung Credit plus, get 30% off Samsung Care+.

From $899.99.⋈. Learn more Buy now Pre-order the new all-in-one Samsung M8 Smart Monitor with Streaming TV now, to receive $100 instant Samsung Credit.

Meet Galaxy S22 Buy now Place works of art anywhere The Frame with Art Mode lets you showcase classic paintings and photos.

Save up to $4,500 on select Samsung Neo QLED 8K TVs, featuring Neural Quantum Processor 8K. Enjoy entertainment from every seat Save up to $2,000 on select Neo 4K QLED TVs with wide viewing angles.

Fresh style with Bespoke Air Purifier Get clean air and a crisp look, with the Bespoke Cube Air Purifier.

Through our products, we’ve saved over 300 million metric tons of CO2 emissions-the equivalent of taking over 65 million cars off the road for a year.

Samsung Electronics

In the process, Samsung used technologies imported from Micron Technology of the U.S for the development of DRAM and Sharp Corporation of Japan for its SRAM and ROM. In 1988, Samsung Electric Industries merged with Samsung Semiconductor & Communications to form Samsung Electronics, as before that, they had not been one company and had not been a leading corporation together, but they were not rivals, as they had been in talks for a time until they finally merged.

On 17 April 2014, Samsung announced it was discontinuing its ebook store effective 1 July 2014 and had partnered with Amazon to introduce the Kindle for Samsung app, that will permit Galaxy device users using Android 4.0 and up to buy and read content from Amazon’s catalog of periodicals and ebooks, and free book service, Samsung Book Deals, that will allow users of the co-branded app to choose one free ebook monthly from a selection provided by Amazon.

In May 2019, for the first time in Europe, 8K demonstration content was received via satellite without the need for a separate external receiver or decoder using a Samsung TV. At the 2019 SES Industry Days conference at Betzdorf, Luxembourg broadcast quality 8K content was encoded using a Spin Digital HEVC encoder, uplinked to a single 33 MHz transponder on SES’ Astra 28.2°E satellites and the downlink received and displayed on a Samsung 82in Q950RB production model TV. Samsung proposed a $17 billion plan to build a chip-making factory in either Arizona, Texas, or New York in 2021.

As of 2018, Samsung sold its printing business to HP. Samsung Electronics produces LCD and LED panels, mobile phones, memory chips, NAND flash, solid-state drives, televisions, digital cinemas screen, and laptops.

Samsung is a major supplier for Apple – first providing memory for the early iPod devices in 2005, and Apple is a key customer for Samsung – in 2012 its component sales were thought to be worth in the region of $8 billion revenue to Samsung – to the point where Apple CEO Tim Cook originally opposed litigation against Samsung wary of the company’s critical component supply chain for Apple.

Unlike the Samsung Experience Shop, the Samsung Entertainment Experience will be run by Samsung trained Best Buy associates.

The suit alleged that, at one point, Samsung and Pelé came close to entering into a licensing agreement for Pelé to appear in a Samsung advertising campaign; Samsung abruptly pulled out of the negotiations.

History & Facts

Samsung, South Korean company that is one of the world’s largest producers of electronic devices.

Samsung specializes in the production of a wide variety of consumer and industry electronics, including appliances, digital media devices, semiconductors, memory chips, and integrated systems.

Samsung in the 1960s acquired more insurance companies as well as an oil refinery, a nylon company, and a department store.

New subsidiaries such as Samsung Heavy Industries, Samsung Shipbuilding, and Samsung Precision Company were established.

Electronics Samsung first entered the electronics industry in 1969 with several electronics-focused divisions.

The late 1970s and early ’80s witnessed the rapid expansion of Samsung’s technology businesses.

Samsung Data Systems was established in 1985 to serve businesses’ growing need for systems development.

Samsung Group engages in the manufacturing and selling of electronics and computer peripherals.

The company operates through following business divisions: Consumer Electronics, Information Technology & Mobile Communications and Device Solutions.

The Consumer Electronics business division provides cable television, monitor, printer, air-conditioners, refrigerators, washing machines and medical devices.

The Information Technology & Mobile Communications business division offers handheld products, communication systems,.

The Device Solutions business division comprises of memory, system large scale integrated circuit and light emitting diode.

The company was founded on January 13, 1969 and is headquartered in Suwon, South Korea.

Post Idea #14: BNP Paribas

Related Articles – Summarized

Ma Banque En Ligne

Vous pouvez exprimer votre solidarité en faisant un don : son montant sera doublé par BNP Paribas et permettra de financer concrètement les actions de nos partenaires actifs sur le terrain.

Offre valable jusqu’au 29/05/2022inclus, pour toute demande en ligne d’un prêt personnel Travaux*.

Recevez 80€* sur votre cagnotte pour chaque parrainage validé.

Et pour votrefilleul : 80€ offerts pour toute ouverture de compte de dépôt en ligne + 1an d’Esprit Libre offert !.

Fonctionnalités et services pour améliorer votre utilisation de la banque au quotidien.

Je découvre Chez BNP Paribas, nos services 100% connectés vous permettent d’ouvrir un compte en ligne en quelques clics et de le gérer distance depuis votre ordinateur, votre tablette ou votre smartphone.

Vous avez le choix de la gestion de votre compte : depuis l’agence la plus proche de chez vous ou en ligne.

BNP Paribas

BNP Paribas S.A. is a French international banking group, born in 2000 from the merger between Banque Nationale de Paris and Paribas.

In May 2000, BNP and Paribas merged to form BNP Paribas, which is thus descended from four founding banking institutions.

The remaining Fortis Bank Netherlands was in the hands of the Dutch Government which merged it with other ABN AMRO holdings it already owned under the name ABN AMRO. In May 2009, BNP Paribas became the majority shareholder of BGL, the State of Luxembourg retaining 34% making BNP the eurozone’s largest bank by deposits held.

On 21 September, the bank’s registered name was changed to BGL BNP Paribas and in February 2010, BGL BNP Paribas became the 100% owner of BNP Paribas Luxembourg.

In December 2021, BNP Paribas announced to exit US retail banking business by selling its Bank of the West to the Bank of Montreal for $16.3bn. In 2021, total revenues of €46.2 billion represent an increase of 4.4% compared to 2020, BNP Paribas remains at the top of the French banks’ ranking in terms of activity.

Belgium: BNP Paribas created BNP Paribas Fortis when it acquired the retail banking assets of the Belgian lender Fortis in 2009.

BNP Paribas is a member of the Global ATM Alliance, a joint venture of several major international banks that allows customers of the banks to use their ATM card or check card at another bank within the Global ATM Alliance with no ATM surcharges when traveling internationally.

BNP Paribas Bank Polska S.A.

Pobierz bezpłatną aplikację na telefon z AppStore.

Pobierz bezpłatną aplikację na telefon z GooglePlay.

Rzeczywista roczna stopa oprocentowania dla przykładu reprezentatywnego kredytu gotówkowego w bankowości elektronicznej na 01.04.2022 r. wynosi 10,45 %. Całkowita kwota kredytu 13 700 zł, całkowita kwota do zapłaty 16 675,29 zł, oprocentowanie stałe 9,99 % w skali roku, całkowity koszt kredytu 2975,29 zł 48 miesięcznych rat.

Wyliczenia dokonane za pomocą kalkulatora mają charakter orientacyjny i dotyczą kredytu gotówkowego w kwocie i o okresie kredytowania wybranych przez Klienta.

Dostępność produktu zależy od analizy zdolności kredytowej Klienta dokonanej przez Bank.

BNP Paribas Bank Polska S.A. z siedzibą w Warszawie przy ul.

Kasprzaka 2, 01-211 Warszawa, zarejestrowany w rejestrze przedsiębiorców Krajowego Rejestru Sądowego przez Sąd Rejonowy dla m.st.

M&G Rating Lowered To Underperform At Exane BNP Paribas

Exane BNP Paribas cut shares of M&G from an outperform rating to an underperform rating in a report published on Tuesday morning, The Fly reports.

They currently have GBX 230 price target on the stock.

A number of other equities analysts have also commented on MGPUF. JPMorgan Chase & Co. raised shares of M&G from an underweight rating to a neutral rating and increased their price target for the stock from GBX 215 to GBX 250 in a report on Thursday, March 31st. Royal Bank of Canada restated a buy rating and issued a $250.00 price objective on shares of M&G in a report on Friday, April 1st. UBS Group increased their price target on shares of M&G from GBX 260 to GBX 275 in a research note on Monday, March 28th. Barclays restated a sell rating and set a GBX 226 price objective.

M&G plc, through its subsidiaries, engages in savings and investment businesses in the United Kingdom and internationally.

The company operates through two segments, Savings & Asset Management and Heritage.

It offers retirement, savings, and investment management solutions to its retail and institutional customers.

BGL BNP Paribas Posts 2% Rise In Net Income To €1.6bn

Excluding the base effect relating to a capital gain on property in 2020, net banking income rose 4%. This increase is the result of strong commercial momentum in the bank’s various business areas, thanks to the teams’ firm commitment to their clients.

To facilitate communication between clients and the bank, regardless of their preferred channel, BGL BNP Paribas continues to expand the range of features it offers.

The bank has also introduced instant payments, making it possible to make instant transfers between BGL BNP Paribas accounts, as well as transfers to or from external institutions.

The BNP Paribas Group has joined the Net Zero Banking Alliance, launched in April 2021 by the UN Environment Programme Finance Initiative, and remains committed to combating climate change.

From 7 to 11 June 2021, BGL BNP Paribas and BNP Paribas Asset Management invited all of the group’s entities in Luxembourg to attend the “Green Week”, organised by employees for employees, to discuss various aspects of sustainable development and raise awareness on how to take action on a daily basis.

BGL BNP Paribas has therefore prepared an ambitious development plan, in keeping with the 2022-25 Strategic Plan that the BNP Paribas Group presented in early 2022, and which focuses on three key priorities: growth, technology and sustainability.

Béatrice Belorgey, Chair of the Executive Committee of BGL BNP Paribas and Country Head of the BNP Paribas Group in Luxembourg, commented: “In a rapidly evolving environment, thanks to the commitment of our teams in supporting our clients, BGL BNP Paribas posted strong performance in 2021. I wish to thank our employees for their engagement, and our clients for their continued trust. The objective of our 2022-2025 strategic plan is to make our bank even more efficient and agile, so as to act in the best interests of our clients, employees and the Luxembourg economy as a trusted, long-term partner”.

Chair Of Housing With Care Taskforce Joins BNP Paribas Real Estate

BNP Paribas Real Estate has appointed Andrew Fyfe as associate director within its healthcare and senior living team.

He has joined from senior living consultancy and research firm Sovereign Property Partnership, which he co-founded and where he served as a lead researcher for two years.

Fyfe is founder and chair of the Scottish housing with care taskforce, which was established by retirement community operators, legal professionals, investors, property executives and local authorities to lobby for housing with care provision for older people.

He is the latest hire recruited into BNPPRE’s healthcare and senior living team following Samantha Rowland as head of healthcare and Colin Rees-Smith as senior director.

They all will look to further BNPPRE’s healthcare and senior living consultancy and transactional services in the UK. ‘Andrew has been at the forefront of lobbying the government and local authorities to increase their housing with care allocation against the backdrop of an ageing population for many years,’ said Rowland.

Fyfe, who will be in based in Edinburgh, added: ‘The private and public sector have an important role to play where housing with care is concerned as supply needs to meet the rising demand.

His role follows appointments across the region including Tara Cowley, head of planning, and Allan Matthews, director of agency and occupier Solutions.

BGL BNP Paribas To Pay Out €197m To Shareholders

Laurent Jansen, CFO, Béatrice Belorgey, Chairwoman of the Executive Committee of BGL BNP Paribas and Country Head of the BNP Paribas Group in Luxembourg, and Étienne Reuter, Chairman of the Board of Directors, on Thursday 7 April presented the bank’s annual results.

As a preamble, they recalled the context of post-pandemic recovery, inflation and low or even negative interest rates, which have affected all banks for several years.

Excluding the capital gain, the net result rose by 7%. It is up by 14% compared to 2019, which the bank considers, for each aggregate, “As the last reference year, in a context of normal activity”.

50% of the consolidated net result will be returned to shareholders in the form of dividends which amounts to a total of €197.15m.Loans, private banking and leasing in the leadThis slight drop is offset by a net banking income that has grown to €1,621.1m which excluding property gains is up by 4% compared to 2020 and 7% compared to 2019.

The bank’s growth affects all types of business lines: retail and corporate banking, and all types of products: real estate loans and investment loans.

Of particular note is a 9% increase in assets under management in the private banking branch, driven by an increase in client portfolios and favourable market conditions in 2021.

The bank has launched a new “Green mobility” loan for individuals who wish to buy an electric vehicle.

Post Idea #15: Ford F-150

Related Articles – Summarized

2023 Ford F-150 Review, Pricing, And Specs

Overview When you think “Pickup truck” the one that probably comes to mind is the Ford F-150.

What’s New for 2023?Ford has added the off-road oriented Rattler trim to the F-150 lineup for 2023.

The Rattler’s positioning in the F-150 lineup provides a more affordable option for buyers who want additional off-road capability but don’t want to shell out for the more expensive Tremor or Raptormodels.

Pricing and Which One to Buy The F-150 is available with multiple body styles and bed lengths.

Engine, Transmission, and Performance The 2023 F-150 is available with several engines-a 290-hp 3.3-liter V-6; a 400-hp 5.0-liter V-8; a 325-hp twin-turbocharged 2.7-liter V-6; a 400-hp twin-turbocharged 3.5-liter V-6; and a 250-hp 3.0-liter diesel V-6.

Buyers will be able to choose between rear- and four-wheel drive with any of the F-150’s available powertrains.

More features will be available as buyers walk up through the F-150’s trim levels, including a rear-facing camera for monitoring a trailer while on the go.

Post Idea #16: Moab Easter Jeep Safari

Related Articles – Summarized

2021 Easter Jeep Safari

The Jeep Safari is an annual event hosted by the Red Rock 4-Wheelers off-road club, where 4-wheelers come to challenge the rough terrain of the backcountry in the Moab area.

One of the busiest weeks of the year in Moab is during the Easter Jeep Safari.

Come prepared for traffic, crowded trails, and difficulty finding campsites.

Have a backup plan if trailhead parking is unavailable.

2022 Easter Jeep Safari Concepts Are Meaner And Greener Than Ever

Jeep’s concept-4×4 blitz that reliably accompanies Moab, Utah’s Easter Jeep Safari off-road festival, has become one of the year’s more entertaining doses of hardcore SUV fun.

Stellantis goes all out for the Easter Jeep Safari in Moab, Utah every year.

The next-most-ambitious rethink in this year’s Easter Jeep Safari concept roundup is likely this unique Bob Concept.

On the less radical side of things, Jeep has taken a Wrangler 4xe plug-in hybrid and given it the armed-services treatment, an homage to the Willys MB that kicked off the brand’s legend in World War II. The Jeep ’41 Concept is an olive-drab 4×4 wearing a relatively modest 2.0-inch Jeep Performance Parts lift, 35-inch off-road tires, half doors and a Warn winch mounted on a steel bumper.

Jeep Jeep D-Coder Concept by JPP. This Jeep D-Coder Concept is essentially a rolling JPP and Mopar catalog on wheels.

Jeep Jeep Birdcage Concept by JPP. The Jeep Birdcage concept is another concept Wrangler that takes pains to bring the outdoors inside for the ultimate al fresco off-roading experience.

The annual Easter Jeep Safari isn’t actually a Stellantis-run event, it’s a yearly gathering for the fans, by the fans.

Jeep Reveals 5 Concepts For Moab Easter Jeep Safari

The Jeep Wrangler Magneto 2.0 Concept is an all-electric terrain dominating off-roader.

The Jeep Grand Cherokee Trailhawk 4xe concept sees Jeep head into the world of hybrid vehicles.

The SUV maker’s vehicles proudly bear the since 1941 badge and the ’41 concept pays tribute to the most famous utility vehicle of them all – the Willys Jeep.

The 20th Anniversary concept is based on the quickest and most powerful Wrangler to date – the Jeep Wrangler Rubicon 392.

Moab Easter Jeep Safari has always been a platform for the American SUV manufacturer to show off its off-roading prowess while peeking into its future.

This year Jeep has bought 5 all-new concepts to Moab three of which show us the brand’s electrified future.

If these concepts are anything to go by then Jeep’s future is something we shouldn’t really be worrying about.

Fast And Futuristic Jeep Magneto Leads Easter Safari Into Moab

Ford may have the F-150 Lightning, but the Jeep Wrangler Magneto 2.0 is lightning-quick.

The all-electric SUV concept is making its debut at the Easter Jeep Safari off-road festival in Moab, Utah, on April 9 along with six other custom vehicles meant to showcase Jeep parts and possibilities for future models.

JEEP RUBICON 20TH ANNIVERSARY CONCEPT. The Rubicon 20th Annversary concept celebrates the extreme off-road trim’s milestone birthday and is likely a thinly-veiled glimpse at a production truck that will be on sale for the 2023 model year.

JEEP ’41 CONCEPT. The Jeep ’41 concept salutes the brand’s past and future.

JEEP D-CODER CONCEPT. The Jeep D-Coder is like a catalog on wheels.

JEEP BOB CONCEPT. The Jeep Bob’s name isn’t a reference to some CJ-driving guy named Robert, but to the “Bobbed” cargo bed of Gladiator pickup, which is a foot shorter than stock for improved off-roading.

JEEP BIRDCAGE CONCEPT. The Jeep Birdcage is a permanently open-air version of the Wrangler Rubicon 4xe that’s had its windshield and windshield wipers removed, and a cowl installed to close the gaps left by them.

Moab During Easter Jeep Safari 2022: Everything You Need To Know

The event known as EJS in beautiful Moab, Utah is a bucket-list must-attend off-road experience! This year’s Easter Jeep Safari 2022 is scheduled to take place from April 9 to April 17.

You can expect thousands enjoying the scenery, joining in with Red Rock 4-Wheelers scheduled trail runs, checking out all the activities at the Moab 4×4 Expo, and hitting the trails.

The nine-day-long event features many organized trail runs that showcase Moab but also require individuals to.

In the immediate Moab area according to RR4W. Each Trail is rated from 1 to 10., with 1 being a county-maintained dirt road, and 10 being an extremely difficult trail only recommended for purpose-built off-road rigs.

During the Safari, RR4W organized trail runs have a designated meeting spot and a designated departure time.

With two off-road expos in Moab during Easter Jeep Safari, it equals twice the fun for families and off-roaders! This additional Moab 4×4 Expo opens to the public after trail rides, 3:00 Pm – 7:00 PM, April 13 through April 15.

Off Road Xtreme is excited to announce we will be onsite at Easter Jeep Safari 2022.

For Jeep, Moab’S Easter Jeep Safari Is A Test Lab For Electric…

Every year in recent history, Jeep shows up to Moab, Utah’s Easter Jeep Safari in style, bringing an assortment of one-off concepts with new hardware, future accessories, and often custom sheetmetal inspired by the brand’s history.

While Jeep is in the name, it’s a grassroots event, hosted by local 4×4 club Red Rock 4-Wheelers Inc. The Jeep brand participates, but does not run it, a casual arrangement that’s mutually beneficial to Jeep loyalists and the company’s engineers alike.

According to Mark Allen, head of Jeep exterior design, “The response last year was awesome.” For 2022, the updated Magneto 2.0 is the most interesting of the seven concepts going to Moab, a lineup that’s lighter on nostalgia than previous outings.

Allen says the Magneto project is “An open laboratory door to what we’re thinking behind the scenes.” Nothing on this Wrangler is intended for production, and there will probably be at least one more iteration of the test mule before Jeep starts teasing any fully-electric production models.

What the Magneto does display is what Jeep is thinking when it comes to electric propulsion off road. Jeep brand boss Jim Morrison says “It will climb up a wall” and the equipment suggests he’s not exaggerating by much.

That’s what Jeep plans to explore with the Magneto 2.0 as they refine the vision for an electrified Jeep.

As for the rest of this year’s Easter Jeep Safari lineup, check out the gallery at the top of the page for a closer look.

Red Rock 4-Wheelers, Inc. –

Unless indicated otherwise – all trails depart at 9AM. Easter Jeep Safari consists of trail rides, mostly day long trips, departing from Moab Utah throughout the 9 day long event.

Permits for filming and the use of drones on Easter Safari trails must be procured through the local BLM office by individuals wanting to participate in such activities during the event.

All participants must check in with the organizers at the Old Spanish Trail Arena during the event to receive the event package which will include a trail pennant, a raffle ticket, a dash plaque, and any required additional information.

Days of event registration, packet pickup is available at the Spanish Trail Arena in the upper level rooms from 7am to 10am the first Saturday through Friday.

Refunds will not be made until after Safari and our treasurer has handled the more pressing Jeep Safari business – please allow up to 4 weeks for processing.

Who are the Trail Leaders? They are Red Rock 4-Wheeler members who do this for the fun of it without payment for their services.

The trail leaders are experienced four wheelers who have been guiding the runs for many years and come to Moab each year from 24 states, 3 Canada and 2 European countries.

Post Idea #17: Renal replacement therapy

Related Articles – Summarized

Renal Replacement Therapy: Options and Choices Marc L. Weber, M.D. Nephrologist University of Minnesota Minneapolis, MN That disclosure slide I have no financial or other disclosures and will not discuss off label use of any medication.

Learning Objectives Identity renal replacement therapy options for patients with end stage renal disease.

Renal replacement therapy should be considered if the patient is experiencing: o o o o A. Hyperkalemia B. Metabolic acidosis C. Fluid overload D. All of the above 2.

73 m2 Education about renal replacement therapy: o Kidney Transplantion Refer to transplant center o o when eGFR < 20 ml/min/1.

Anonymous For people >80yo, which disease has the highest mortality? A. ESKD on dialysis B. Cancer C. CHF D. AMI Adjusted all-cause mortality in 2012 Age 80+ USRDS 2014 ADR Where do dialysis patients die? USRDS 2014 ADR Where do dialysis patients want to die? A. Hospital B. ICU C. Dialysis unit D. Home In the last month of life 80% of dialysis patients hospitalized o o o 50% are in the ICU 30% received aggressive/invasive procedures 20% referred to hospice < half the national average 75% of dialysis patients do not want to die in the hospital Wong.

2012 Take Home Points Planning ahead is key to improve outcomes for dialysis patients Education allows patients to get the care that’s right for them Hemodialysis catheters associated with mortality Hospice referral is underutilized Multidisciplinary team approach to care is required for improved outcomes Self Assessment Questions 1.

Renal replacement therapy should be considered if the patient is experiencing: o o o o A. Hyperkalemia B. Metabolic acidosis C. Fluid overload D. *All of the above* Rationale: Dialysis can help regulate potassium, acid/base balance and fluid.

Continuous Renal Replacement Therapy

Continuous renal replacement therapy is commonly used to provide renal support for critically ill patients with acute kidney injury, particularly patients who are hemodynamically unstable.

6 The present article provides an overview of key issues in the management of RRT in the critically ill patient, focused primarily on the use of continuous renal replacement therapy.

Schefold J.C., von Haehling S., Pschowski R. The effect of continuous versus intermittent renal replacement therapy on the outcome of critically ill patients with acute renal failure: a prospective randomized controlled trial.

Bagshaw S.M., Berthiaume L.R., Delaney A., Bellomo R. Continuous versus intermittent renal replacement therapy for critically ill patients with acute kidney injury: a meta-analysis.

Pannu N., Klarenbach S., Wiebe N., Manns B., Tonelli M. Alberta Kidney Disease N. Renal replacement therapy in patients with acute renal failure: a systematic review.

Pea F., Viale P., Pavan F., Furlanut M. Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy.

Okon T.R., Vats H.S., Dart R.A. Palliative medicine referral in patients undergoing continuous renal replacement therapy for acute kidney injury.

Renal Replacement Therapy: A Practical Update

Acute kidney injury is defined as an abrupt decrease in kidney function, with the most severe form requiring some method of renal replacement therapy.

The use of RRT is required in 5-10% of critically ill patients who develop severe AKI. Renal replacement therapy can be provided as either intermittent hemodialysis or one of the various modes of continuous renal replacement therapy, with CRRT potentially conferring an advantage with respect to renal recovery and dialysis independence.

Continuous renal replacement therapy may be run in different modes of increasing complexity depending on a given patient’s clinical needs.

Regional citrate anticoagulation is recommended as the therapy of choice for the majority of critically ill patients requiring CRRT. RéSUMé: L’insuffisance rénale aiguë se définit par une réduction subite de la fonction rénale, et sa forme la plus grave nécessite un type de traitement substitutif.

Le traitement substitutif de l’insuffisance rénale peut prendre la forme d’une hémodialyse intermittente ou de l’un des divers modes de traitement substitutif de l’insuffisance rénale en continu, ce second type de traitement conférant potentiellement un avantage en matière de récupération de la fonction rénale et d’indépendance de la dialyse.

Le traitement substitutif de l’insuffisance rénale en continu peut être réalisé selon différents modes de complexité croissante en fonction des besoins cliniques d’un patient donné.

Une anticoagulation régionale au citrate est recommandée comme traitement de choix pour la majorité des patients critiques nécessitant un traitement substitutif de l’insuffisance rénale en continu.

Renal Replacement Therapy » Division Of Nephrology, Hypertension & Renal Transplantation » College Of Medicine » University Of Florida

Renal replacement therapy is a term used to encompass life-supporting treatments for renal failure.

Renal replacement therapy replaces nonendocrine kidney function in patients with renal failure.

Techniques include intermittent hemodialysis, continuous hemofiltration and hemodialysis, and peritoneal dialysis.

All modalities exchange solute and remove fluid from the blood, using dialysis and filtration across permeable membranes.

Dialysis and filtration can be done intermittently or continuously.

Continuous therapy is used exclusively for acute renal failure; benefits over intermittent therapy are improved tolerability as a result of slower removal of solute and water.

Renal Replacement Therapy

From: Critical Care Nephrology, 2019.Prevention and Management of Acute Kidney Injury Indications for and Timing of Initiation of Renal Replacement TherapyIn clinical practice, there are wide variations in the timing of initiation of RRT for patients with AKI.574 Widely accepted indications for initiation of RRT include volume overload unresponsive to diuretic therapy, severe metabolic acidosis or hyperkalemia, despite appropriate medical therapy, and overt uremic manifestations, including encephalopathy, pericarditis, and uremic bleeding diathesis.

More recently, two clinical trials have compared differing strategies of early and delayed initiation of RRT in patients with AKI. The Effect of Early vs. Delayed Initiation of Renal Replacement Therapy.

Home dialysis therapies such as PD should be considered as first choice for KRT, especially when patients have significant residual renal function or have an impending living donor transplant.

This modality cannot be used in patients who have had recent intraabdominal surgery, so in general, its role is quite limited in the perioperative setting, with the exceptionof patients who are maintained on this therapy for end-stage renal disease preoperatively.

Is a general term encompassing a range of different treatment modalities for patients with what was formally termed acute renal failure and end-stage kidney disease, which are now called acute kidney injury stage 332 and chronic kidney disease stage 5,20 respectively.

In a minority of cases specific management strategies may be appropriate to halt progression, such as immunosuppression for patients with renal vasculitis or lupus nephritis.

The most frequently applied RRTs in patients with acute renal failure are intermittent hemodialysis, continuous venovenous hemofiltration, and continuous venovenous hemodiafiltration.

Renal Replacement Therapy

Dr. Takashi Shigematsu is currently the emeritus professor of the department of nephrology at the Wakayama Medical University School of Medicine, Japan.

He is now actively working as Director of Division of Nephrology and Clinical Research Center in Rinku General Medical Center.

He is also a member of the International Society of Nephrology and the American Society of Nephrology.

His research interests focus on Mineral and Bone Disorder associated with chronic kidney disease including vascular calcification, Senescence.

He has been investigating and working in the fields of hemodialysis and vascular access, peritoneal dialysis, blood purification medicine in acute kidney injury, and kidney transplantation.

His professional interests include Nephrology and Renal Replacement Therapy.

Renal Replacement Therapy

Renal replacement therapy is therapy that replaces the normal blood-filtering function of the kidneys.

It is used when the kidneys are not working well, which is called kidney failure and includes acute kidney injury and chronic kidney disease.

Renal replacement therapy also includes kidney transplantation, which is the ultimate form of replacement in that the old kidney is replaced by a donor kidney.

In the context of chronic kidney disease, they are more accurately viewed as life-extending treatments, although if chronic kidney disease is managed well with dialysis and a compatible graft is found early and is successfully transplanted, the clinical course can be quite favorable, with life expectancy of many years.

In certain acute illnesses or trauma resulting in acute kidney injury, a person could very well survive for many years, with relatively good kidney function, before needing intervention again, as long as they had good response to dialysis, they got a kidney transplant fairly quickly if needed, their body did not reject the transplanted kidney, and they had no other significant health problems.

Continuous renal replacement therapy – continuous renal replacement therapy is a form of dialysis therapy used in critical care settings.

Continuous venovenous hemodiafiltration… intermittent renal replacement therapy intermittent hemodialysis intermittent venovenous hemodialysis.

Post Idea #18: Kidney disease

Related Articles – Summarized

Chronic Kidney Disease

Learn more from kidney doctor Andrew Bentall, M.D. I’m Dr. Andrew Bentall, a kidney doctor at Mayo Clinic.

I look after patients with kidney disease, either in the early stages, or with more advanced kidney disease considering dialysis and transplantation as treatment options.

Chronic kidney disease is a disease characterized by progressive damage and loss of function in the kidneys.

There are quite a few things that can cause or put you at higher risk for chronic kidney disease.

Even before any symptoms appear, routine blood work can indicate that you might be in the early stages of chronic kidney disease.

Urine tests can reveal abnormalities and give clues to the underlying cause of the chronic kidney disease.

Learning you have chronic kidney disease and learning how to live with it can be a challenge.

Kidney Disease

Your kidneys filter extra water and wastes out of your blood and make urine.

Kidney disease means your kidneys are damaged and can’t filter blood the way they should.

You are at greater risk for kidney disease if you have diabetes or high blood pressure.

If you experience kidney failure, treatments include kidney transplant or dialysis.

Other kidney problems include acute kidney injury, kidney cysts, kidney stones, and kidney infections.

Chronic Kidney Disease Initiative

Kidneys that function properly are critical for maintaining good health more than one in seven American adults are estimated to have chronic kidney disease.

CKD can progress to kidney failure and early cardiovascular disease.

Kidney failure treated with dialysis or kidney transplant is called end-stage renal disease.

Learn more about ESRD. Not all patients with kidney disease progress to kidney failure.

To help prevent CKD and lower the risk for kidney failure, control risk factors for CKD, get tested yearly, make lifestyle changes, take medicine as needed, and see your health care team regularly.

40% of people with severely reduced kidney function are not aware of having CKD. Every 24 hours, 360 people begin dialysis treatment for kidney failure.

In the United States, diabetes and high blood pressure are the leading causes of kidney failure, accounting for 3 out of 4 new cases.

Causes, Risk Factors, Stages

Kidney disease can affect your body’s ability to clean your blood, filter extra water out of your blood, and help control your blood pressure.

Acute kidney disease causes: If your kidneys suddenly stop working, doctors call it acute kidney injury or acute renal failure.

Chronic kidney disease causes: When your kidneys don’t work well for longer than 3 months, doctors call it chronic kidney disease.

High blood pressure creates wear and tear on your blood vessels, including those that go to your kidneys.

Polycystic kidney disease, a genetic condition where fluid-filled sacs form in your kidneys.

A kidney biopsy, where tissue from your kidney is sent to a lab for testing to try and figure out the cause of your kidney issues.

Once your kidneys can’t keep up with waste on their own, you’ll have treatment for end-stage kidney disease.

Stages Of Kidney Disease

Learn what the stages of chronic kidney disease refer to and how stages are based on the eGFR test.

The stages are based on the eGFR test result and how well your kidneys work to filter waste and extra fluid out of your blood.

As the stages go up, kidney disease gets worse and your kidneys work less well.

What do the stages of chronic kidney disease refer to?

The task force has been seeking the input of kidney disease experts to come up with the best way to make the eGFR test as accurate as possible.

The American Kidney Fund advised the task force to remove race from the eGFR so there is no bias in testing kidney function.

Being diagnosed with chronic kidney disease can be an overwhelming experience.

Stages Of Chronic Kidney Disease

WHY YOU NEED A KIDNEY DOCTOR. A nephrologist, also known as a kidney doctor, is the most qualified doctor to help you manage kidney disease.

Ask your doctor for a referral to a nephrologist when your eGFR is between 30-44.

Kidney Disease

Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney.

Kidney disease usually causes a loss of kidney function to some degree and can result in kidney failure, the complete loss of kidney function.

Kidney failure is known as the end-stage of kidney disease, where dialysis or a kidney transplant is the only treatment option.

Chronic kidney disease is defined as prolonged kidney abnormalities that last for more than three months.

Acute kidney disease is now termed acute kidney injury and is marked by the sudden reduction in kidney function over seven days.

Polycystic Kidney Disease is a genetic disease caused by mutations in the PKD1, PKD2, and PKHD1 genes.

The most common form of kidney disease in cancer patients is Acute Kidney Injury which can usually be due to volume depletion from vomiting and diarrhea that occur following chemotherapy or occasionally due to kidney toxicities of chemotherapeutic agents.

Post Idea #19: Calcium gluconate

Related Articles – Summarized

Calcium Gluconate: Benefits, Side Effects, Dosage, And Interactions

Calcium is used medically in many forms, including calcium chloride, calcium formate, calcium citrate, or calcium gluconate.

Oral calcium gluconate can also be used as a calcium supplement but is probably not be the best option for use as a long-term solution.

Calcium Channel Blocker Overdose Blood pressure medications that are known as calcium channel blockers lower blood pressure by slowing down the ability of the calcium to react across muscle cell membranes.

Experts recommend intravenous calcium via either calcium gluconate or calcium chloride for overdoses of calcium channel blockers.

Many of the side effects of calcium gluconate are similar to signs of elevated levels of calcium in the bloodstream.

Intravenous Calcium Gluconate Most emergency doses of calcium gluconate are given intravenously, either as a bolus or as a drip infusion given over time.

Your healthcare provider may prescribe calcium gluconate to help control calcium levels depending on your condition.

Calcium Gluconate

Calcium gluconate is a medication used to manage hypocalcemia, cardiac arrest, and cardiotoxicity due to hyperkalemia or hypermagnesemia.

This activity outlines the indications, action, and contraindications for calcium gluconate as a valuable agent in managing hypocalcemia, cardiac arrest, cardiotoxicity due to hyperkalemia or hypermagnesemia, and other disorders as applicable.

This activity will highlight the mechanism of action, adverse events, and other key factors.

The activity is pertinent for members of the healthcare team who are engaged in the management of hypocalcemia, cardiac arrest, cardiotoxicity due to hyperkalemia or hypermagnesemia, and related conditions.

Calcium Gluconate: Uses, Dosage, Side Effects, Interactions, Warning

Calcium Gluconate is an over-the-counter and a prescription medicine used to treat the symptoms of Hypocalcemia and as a Calcium Supplement.

Calcium Gluconate belongs to a class of drugs called Antidotes, Other; Calcium Salts.

These are not all the possible side effects of Calcium Gluconate.

DESCRIPTION. Calcium Gluconate is the calcium salt of gluconic acid, an oxidation product of glucose, and contains 9.3% calcium, which is about one-third of the calcium in strength of calcium chloride USP. Since it is soluble to the extent of only one part in 30 parts of cold water, the 10% solution is supersaturated and is stabilized by the addition of calcium saccharate tetrahydrate 0.46% w/v.

Each mL contains 98 mg of calcium gluconatemonohydrate, 4.6 mg of calcium saccharate tetrahydrate, and Water for Injection USP, q.s. Each mL provides 9.3 mg of calcium.

View Coupon INDICATIONS. Calcium gluconate is used to treat conditions arising from calcium deficiencies such as hypocalcemic tetany, hypocalcemia related to hypoparathyrodism and hypocalcemia due to rapid growth or pregnancy.

When injected intravenously, calcium gluconate should be injected through a small needle into a large vein in order to avoid too rapid increase in serum calcium and extravasation of calcium solution into the surrounding tissue with resultant necrosis.

Calcium Gluconate

Calcium gluconate is made by mixing gluconic acid with calcium carbonate or calcium hydroxide.

10% calcium gluconate solution is the form of calcium most widely used in the treatment of low blood calcium.

This form of calcium is not as well absorbed as calcium lactate, and it only contains 0.93% calcium ion.

Calcium gluconate is used as a cardioprotective agent in people with high blood potassium levels, with one alternative being the use of calcium chloride.

The calcium gluconate reacts with hydrofluoric acid to form insoluble, non-toxic calcium fluoride.

In addition to a 2.5% calcium gluconate gel being applied directly to the chemical burn, the person may also receive calcium gluconate supplements because the fluoride ion precipitates serum calcium, causing hypocalcemia.

Cases of cardiac arrest in which it is still recommended include high blood potassium, low blood calcium such as may occur following blood transfusions, and calcium channel blocker overdose.


DOSAGE AND ADMINISTRATION. Contains 100 mg of calcium gluconate per mL which contains 9.3 mg of elemental calcium Administer intravenously via a secure intravenous line See Full Prescribing Information for dilution instructions, administration rates, and appropriate monitoring Individualize the dose within the recommended range in adults and pediatric patients depending on the severity of symptoms of hypocalcemia, the serum calcium level, and the acuity of onset of hypocalcemia.

Calcium Gluconate Injection contains 100 mg of calcium gluconate per mL which contains 9.3 mg of elemental calcium.

Table 1 provides dosing recommendations for Calcium Gluconate Injection in mg of calcium gluconate for neonates, pediatric and adult patients.

Measure serum calcium every 4 to 6 hours during intermittent infusions with Calcium Gluconate Injection and measure serum calcium every 1 to 4 hours during continuous infusion.

Single dose vial: 1,000 mg per 10 mL Single dose vial: 5,000 mg per 50 mL Pharmacy bulk package: 10,000 mg per 100 mL. Each mL of Calcium Gluconate Injection contains 9.3 mg of elemental calcium.

Avoid administration of Calcium Gluconate Injection in patients receiving cardiac glycosides; if considered necessary, administer Calcium Gluconate Injection slowly in small amounts and monitor ECG closely during administration.

Solubility in water: 3.5 g/100 mL at 25°C. Calcium Gluconate Injection is available as 1,000 mg per 10 mL or 5,000 mg per 50 mL in a single-dose vial, or 10,000 mg per 100 mL in a pharmacy bulk package.

What Is Calcium Gluconate?

Calcium gluconate is calcium combined with glucose, or blood sugar.

Calcium occurs naturally in foods like yogurt, milk, and cheese, and it is most readily absorbed when taken in conjunction with vitamin D. There are several different ways that calcium gluconate can be administered.

As with any drug, there are certain side effects associated with calcium gluconate.

Only a physician can determine whether the side effects experienced while taking calcium gluconate are cause for discontinuing treatment.

Calcium lactate gluconate, commonly called calcium gluconolactate, is calcium gluconate mixed with calcium lactate.

The combination of these two calcium salts is high in calcium.

Calcium lactate gluconate is commonly used as a food additive in foods that are enriched with calcium.

Calcium Gluconate Dosage Guide + Max Dose, Adjustments

Applies to the following strengths: 500 mg; 100 mg/mL; 650 mg; 1000 mg; 1 g/50 mL-NaCl 0.9%; 1 g/100 mL-NaCl 0.9%; 2 g/100 mL-NaCl 0.9%; 1 g/50 mL-D5%; 20 mg/mL-NaCl 0.67%; 1 g/100 mL-NaCl 0.8%; 2 g/50 mL-NaCl 0.9%; 1 g/25 mL-NaCl 0.9%; 1 g/100 mL-D5%; 2 g/100 mL-D5%; 20 g/1000 mL-NaCl 0.9%. Usual Adult Dose for: Usual Geriatric Dose for: Usual Pediatric Dose for: Additional dosage information: Usual Adult Dose for Hypocalcemia.

Comments:-Adjust dose based on symptom severity, serum calcium level, and acuity of hypocalcemia onset.

The injectable product contains 100 mg calcium gluconate per mL, equal to 9.3 mg elemental calcium.

Recommended Dietary Allowance for elemental calcium:18 to 50 to years: 1000 mg.51 to 70 years, male: 1000 mg.51 to 70 years, female: 1200 mg.

Recommended Dietary Allowance for elemental calcium:0 to 6 months: 200 mg.7 to 12 months: 260 mg.1 to 3 years: 700 mg.4 to 8 years: 1000 mg.9 to 18 years: 1300 mg.

Initiate at the lowest recommended dose for the age; measure serum calcium every 4 hours during intravenous administration.

Bolus IV administration: Dilute dose to a 10 to 50 mg/mL concentration; administer slowly; monitor patient, vitals, and electrocardiograph during administration:-Continuous IV infusion: Dilute dose to a 5.8 to 10 mg/mL concentration; administer at correct rate for age; monitor patient, vitals, and ECG during administration.

Post Idea #20: Google Shopping

Related Articles – Summarized

Google Shopping

Google Shopping, formerly Google Product Search, Google Products and Froogle, is a Google service created by Craig Nevill-Manning which allows users to search for products on online shopping websites and compare prices between different vendors.

Google announced at its Marketing Live event in May 2019 that the new Google Shopping will integrate the existing Google Express marketplace into a revamped shopping experience.

In the US, Google Shopping is accessible from the web and mobile apps, available on Android and iOS. Google Shopping is also available in France, accessible from the web only.

On the web, shoppers can either go to the Google Search homepage to enter a search query and then select the Shopping tab under the navigation bar, or go directly to the Google Shopping site to search for specific items, browse departments, and see trending items and promotional offers.

Alongside the announcement of an immediate re-brand to Google Shopping on May 31, 2012, Google also announced that in late 2012, it would change the service to use a “Pay-to-play” model, where merchants would have to pay Google to list their products on the service, with results influenced by both relevance and the bid amounts they pay.

Microsoft’s Bing also attacked the move in an advertising campaign known as “Scroogled,” which called Google out for using “Deceptive advertising practices” and suggesting that users use its competing Bing Shopping service instead. Google also revealed plans to integrate Google Catalogs with Google Shopping, to give users “More ways to find ideas and inspiration as you shop and engage with your favorite brand.”

In March 2018, Google introduced Shopping Actions, a commission based model, where customers can shop “On the Google Assistant and Search with a universal cart, whether they’re on mobile, desktop, or even a Google Home device”.

Post Idea #21: Wireless local loop

Related Articles – Summarized

Local loop is a circuit line from a subscriber’s phone to the local central office.

The implementation of local loop of wires is risky for the operators, especially in rural and remote areas due to less number of users and increased cost of installation.

The solution for it is the usage of wireless local loop which uses wireless links rather than copper wires to connect subscribers to the local central office.

PSTN:It is Public Switched Telephone Network which is a circuit switched network.

Switch Function:Switch Function switches the PSTN among various WANUs.

WLL Controller: It controls the wireless local loop component with WASU.AM: It is short for Access Manager.

Much more secure due to digital encryption techniques used in wireless communication.

Wireless Local Loop

Wireless local loop, is the use of a wireless communications link as the “Last mile / first mile” connection for delivering plain old telephone service or Internet access to telecommunications customers.

Multichannel Multipoint Distribution Service and Local Multipoint Distribution Service were the first true multi point services for wireless local loop.

These devices all describe the customer premises wireless system as the Subscriber Unit, and the operator transmitter delivering the last mile local loop services as the Access Point.

Originally designed for short range mobile internet and local area network access, IEEE 802.11 has emerged as the de facto standard for unlicensed Wireless Local Loop.

Interference caused the majority of unlicensed wireless services to have much higher error rates and interruptions than equivalent wired or licensed wireless networks, such as the copper telephone network, and the coaxial cable network.

The Wireless Local Loop market is currently an extremely high growth market, offering internet service providers immediate access to customer markets without having to either lay cable through a metropolitan area MTA, or work through the ILECs, reselling the telephone, cable or satellite networks, owned by companies that prefer to largely sell direct.

LMDS. IEEE 802.11, originally designed for short range mobile internet and network access service, it has emerged as the facto standard for Wireless Local Loop.

What Is A Wireless Local Loop?

Wireless Local Loop is a generic word for an access system that connects users to the local telephone company’s switch via wireless links rather than traditional copper cables.

WLL systems enable the rapid deployment of basic phone service in areas where geography or telecommunications development makes traditional wireline service prohibitively expensive.

WLL systems are easy to integrate with a modified public telephone network, and they can usually be installed within a month of acquiring equipment, much faster than traditional wiring, which can take months to set up and years to increase the capacity to meet the growing demand for communication services.

Digital WLL systems can offer higher-speed fax and data services in addition to providing better speech quality than analog systems.

Existing operations support systems and transmission and distribution systems are also compatible with WLL technology.

Benefits of Using WLL. WLL systems are scalable, allowing operators to continue to use their existing infrastructure as the system grows.

WLL customers use a radio unit connected to the PSTN via a local base station to obtain phone service.

Principles Digital Communication System & Computer Networks

A number of remote stations communicate with the base station through radio.

The system consists of a base station and a number of remote stations.

Since the base station can support only two radio channels at a time, only two remote telephones can use the system.

The system consists of a base station and number of remotes.

The number of channels will be 12 with a channel spacing of 2.5MHz. The modulation in both directions can be QPSK. Alternatively, the base station can use FSK for transmission, and remote stations can use QPSK-this scheme has the advantage that the remote station electronics will be less complex because demodulation of FSK is much easier than demodulation of QPSK. Base station and the remote stations transmit a power of 2 watts.

Figure 12.5: Digital wireless local loop using TDM/TDMA. The remote stations will use the TDMA for accessing the base station.

Digital local loops using the TDM/TDMA technique provide wireless connectivity between a number of remote stations and a central station.

Wireless Local Loop Basics

There are various ways internet can be provided to the users such as fiber optic cable, DSL line and wireless connectivity.

Providing fixed wireless connection for broadband internet is referred as WLL or Wireless Local Loop.

Microwave frequencies are used to provide wireless broadband connection.

The local loop can be referred as “Last mile” of the telecom network which resides between Central office(CO) and user’s location.

Benefits of WLL. Channel between transmitter and receiver is invariant and hence less complex algorithms are needed in WLL network.

Frequencies are 10 times higher than cellular mobile system, and hence higher bandwidth and high gain antennas can be employed.

Milimeter wave frequencies above 10 GHz and upto 300 GHz are used for WLL. In US, FCC has set aside about 15 bands for use in commercial fixed wireless service from 2 GHz to 40 GHz frequency range.

The systems using such technology are known as cellular systems.

System based on Macro Cellular technology such as GSM /CDMA /DAMPS were adapted from cellular mobile system and have cell radii in few kilometers in urban environment, whereas system based on Micro Cellular architecture such as DECT is an extension of Cordless Telephone System and have cell radii of few hundred meters in typical urban environments.

ESSENTIAL REQUIREMENTS OF WLL ] The following are essential requirements of WLL systems which are to be deployed for providing last mile connectivity: 1) Quality Since a WLL system serves as the access line for fixed telephone sets, it must provide the same level of quality as conventional telephone systems with respect to such aspects as speech quality, grade of service, connection delay and speech delay.

4) Interference with other wireless systems A WLL system must not cause any interference with the operation of existing systems, such as microwave communications and broadcasting systems.

Analog Cellular Given its wide availability resulting from serving high-mobility markets, there is significant momentum to use analog cellular for WLL. There are currently three main analog cellular system types operating in the world: advanced mobile phone system, Nordic mobile telephone, and total access communications systems.

Main features of CorDECT WLL systems are given below: i) CorDECT system is Micro Cellular Wireless Access system.

Main features of CDMA WLL systems are given below: i) CDMA systems are based on Macro Cellular technology.

Post Idea #22: Boeing 777

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Boeing 777

In 1978, Boeing unveiled three new models: the twin-engine Boeing 757 to replace its 727, the twin-engine 767 to challenge the Airbus A300, and a trijet 777 concept to compete with the DC-10 and L-1011.

The first generation of Boeing 777 models, the -200, -200ER, and -300 have since been known collectively as Boeing 777 Classics.

In January 2016, Boeing confirmed plans to reduce the production rate of the 777 family from 8.3 per month to 7 per month in 2017 to help close the production gap between the 777 and 777X created by a lack of new orders.

Unlike smaller airliners like the Boeing 737, no current 777 wings have winglets; instead, the exceptionally long raked wings of the 777 serve the same drag-reducing function.

In 2011, Flight International reported that Boeing is considering replacing the Signature Interior on the 777 with a new interior similar to that on the 787, as part of a move towards a “Common cabin experience” across all Boeing platforms.

In the 2000s, Boeing began studying the conversion of 777-200ER and -200 passenger airliners into freighters, under the name 777 BCF. The company has been in discussion with several airline customers, including FedEx Express, UPS Airlines, and GE Capital Aviation Services, to provide launch orders for a 777 BCF program.

777 Business Jet – the Boeing Business Jet version of the 777 that is sold to corporate customers.

United Airlines Is Delaying The Return Of Boeing 777 Planes After Dozens Were Grounded Last Year Due To An Engine Failure

United grounded its fleet of Boeing 777s carrying Pratt & Whitney engines following an incident last year.

AP. United Airlines is delaying the return of Boeing 777 planes that contain the same engines as one that failed and shed debris over Denver last year.

Dozens of planes containing Pratt & Whitney 4000 engines have been grounded since the incident in February last year.

The Boeing 777 jet had been headed for Honolulu, Hawaii, but was forced to return to the airport when its right engine failed.

“Due to the delay in the return of our PW777 aircraft to active service, the May flight schedule is being reconfigured to account for the lack of these aircraft,” United told pilots in a note circulated on Friday and seen by CNBC. CNBC reported that 52 United planes carried the Pratt & Whitney 4000 engines.

“We continue to work conscientiously with Boeing, Pratt & Whitney and the FAA to safely return these aircraft to service soon, and our current plan will allow them to return in the second half of May,” United told Insider in a statement.

In March, China grounded its entire fleet of Boeing 737-800 passenger jets after a China East airliner with 132 people crashed in the southern Chinese region of Guangxi.

Boeing: 777

The Boeing 777’s unique combination of superior range, outstanding fuel efficiency and passenger-preferred comfort has created long-range success for carriers around the world.

The 777-300ER now gives operators a perfect opportunity to extend that success.

Recent upgrades further reduce costs and boost revenue, and the 777’s flying experience is still number one with passengers.

A more profitable fleet and more satisfied passengers.

SeatGuru Seat Map American Airlines

All seats feature a 15.4-inch HD-capable touchscreen monitor with a selection of up to 75 movies, more than 150 TV programs, More than 350 audio selections, and up to 15 games.

Every Main Cabin Extra and Economy class seatback has an 8.9-inch HD-capable touchscreen monitor with a variety of movies, TV programs, games, and audio selections available.

Boeing 777’S Landing Scare Prompts French Probe

French air-safety officials launched an investigation into the cause of an Air France flight-control incident that led pilots of a Boeing 777 to abort a landing at Paris-Charles de Gaulle airport.

Air France Flight AF011 from New York landed safely on its second attempt Tuesday morning after pilots told air traffic-controllers the aircraft was unresponsive as it approached the runway the first time.

Bureau d’Enquêtes et d’Analyses, France’s air-crash authority, termed the incident “Serious” and said on Twitter Wednesday that it is analyzing the flight data.

The BEA cited “Instability of flight controls” in the final stages of the flight, as well as “Hard controls” and “Flight-path oscillations.”

A few moments later, a pilot said: “The airplane is pretty much going nuts.” The air traffic controller responded: “I’ve seen on the radar, it swayed to the left.”

“Air France understands and regrets the discomfort felt by customers,” the company said.

The go-round procedure is used by all airlines “To guarantee the safety of flights and passengers, which is an absolute necessity for Air France.”

Post Idea #23: VF Corporation

Related Articles – Summarized

VF Corporation

VF Corporation is an American global apparel and footwear company founded in 1899 and headquartered in Denver, Colorado.

In 1969, the H.D. Lee Company was acquired, accompanied by Vanity Fair Mills changing to VF Corporation.

Eric C. Wiseman became President, CEO, and Chairman in 2008, the same year that VF would acquire Mo Industries Holdings, parent company of sportswear brands Splendid and Ella Moss.

In 2021, VF announced a definitive agreement to sell a portion of its occupational Work segment to a subsidiary of Redwood Capital Investments, LLC. On June 28, 2021, the sale was finalized, and the 11 divested brands became part of a new standalone company, Workwear Outfitters.

In September 2021, it was announced that the former president of emerging brands of VF Corporation Travis Campbell will acquire the Eagle Creek brand.

The outlet mall, located in Vanity Fair’s old manufacturing mills, was dubbed the official “Outlet Capital of the World.” The corporate name was changed from VF Outlet Village to VF Outlet Center in 2008.

The VF Outlet business moved to Kontoor Brands Inc, established as a separate company in May 2019.

Salaries At VF Corporation

Benefits information is taken from job posted on Indeed.

Common questions about salaries at VF CorporationHow much does VF Corporation in the United States pay?The average VF Corporation salary ranges from approximately $24,583 per year for Supply Chain Specialist to $186,011 per year for Director of Marketing.

Average VF Corporation hourly pay ranges from approximately $9.63 per hour for Retail Sales Associate to $34.32 per hour for Sales Associate.

Salary information comes from 499 data points collected directly from employees, users, and past and present job advertisements on Indeed in the past 36 months.

Please note that all salary figures are approximations based upon third party submissions to Indeed.

These figures are given to the Indeed users for the purpose of generalized comparison only.

Minimum wage may differ by jurisdiction and you should consult the employer for actual salary figures.

Learn more about their journey in :Technical workwear takes a trip outside to explore.

Discover the new Survivalist range from Dickies in :Environmentally friendly and made to last-‘s Renewed Program makes it possible through their circular model.

The tech industry is uniquely poised to attract new individuals from other spaces during The Great Resignation, and customers will benefit, too.

Learn more about her, and her inspiring experience in the program: bit.

With the support of , a brand new skate park will open this fall in Fort Worth featuring a skate plaza, green spaces, skateable pathways, and a dog park:Insider’s Amir Ismael says, “If you’re looking for winter boots that will last a lifetime, you’ve just found them.” Check out their full review of ‘s re-released Super Boots:The future of fashion gives makers of all kinds a way to bring their designs to life.

Jean-Pierre Aramouni, one of Foundry’s current Entrepreneurs in Residence, tells us about his journey to entrepreneurship and how the Foundry is helping him on his path in this new interview: bit.

Learn more about their new upcycling program:From our factories to our retail stores, our products make quite the journey to get to consumers.

Post Idea #24: The Lego Group

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The Lego Group

In 2003, The Lego Group won a lawsuit in Norway against the marketing group Biltema for its sale of Coko products, on the grounds that the company used product confusion for marketing purposes.

The Lego Group has attempted to trademark the “Lego Indicia”, the studded appearance of the Lego brick, hoping to stop production of Mega Bloks.

First half-year sales were driven by double-digit growth across all geographical regions and strong product innovation on themes such as Lego Ninjago, Lego Elves and Lego Creator.

Each park features large-scale Lego models of famous landmarks and miniature Lego models of famous cities, along with Lego themed rides.

In July 2005, the Lego Group announced that it had reached a deal with private investment company the Blackstone Group to sell all four parks for €375 million to the Blackstone subsidiary Merlin Entertainments.

The first Lego store in India was opened in Chennai, Tamil Nadu in March 2014 by Funskool, under licence from the Lego Group.

Eventually, The Lego Group opted out of the video game business and Lego Interactive was shut down.

The LEGO Group And The LEGO Foundation

Since 2015, the LEGO Foundation, the LEGO Group and UNICEF have been empowering children to become creative, engaged, lifelong learners through play.

What we’re doing in play Building on existing work in South Africa over the last four years, where we trained teachers on learning through play, the LEGO Foundation and UNICEF aim to fundamentally redefine the meaning of teaching and learning in the period from birth to nine years old.

Together we aim to leverage our combined global presence and brand power in 190 countries, including the 100 million families the LEGO Group reaches in 140 countries, to promote the importance of investing in learning through play to equip children with the 21st-century skills they need to thrive.

The LEGO Foundation and UNICEF have also increased understanding of how adults can engage in more playful interactions with children and increase their capacity to stimulate learning through play.

Together, the LEGO Foundation, the LEGO Group and UNICEF introduced play as a means to provide psycho-social support to conflict-affected children.

Since 2015, the LEGO Group and the LEGO Foundation has donated LEGO® PLAY Boxes and helped to train practitioners and staff reaching around 500,000 vulnerable and conflict-affected children in Egypt, Iraq, Jordan and Ukraine.

The LEGO Foundation is dedicated to building a future where learning through play empowers children to become creative, engaged, lifelong learners.


The development of these products and activities is guided by the company’s vision of “Idea, Exuberance, and Values” and the shared belief that children are of vital concern to LEGO. The company’s goal is for the LEGO logo and name to be known among families with children as the strongest brand in the world.

LEGO figures are introduced and are the biggest selling product to date; LEGO enters the U.S. market.

Part of LEGO’s goal in doing so was to raise membership by 50 percent by the end of 1997.CURRENT TRENDS. LEGO is accelerating the rate at which it introduces new products.

For many years it has collaborated with the Media Lab at the Massachusetts Institute of Technology to lay the foundation for such products as LEGO Mindstorms, a child-friendly programming language, digital LEGO bricks, and CD-ROM titles, among other new products.

In early 1998 LEGO announced an agreement with Lucas Licensing Ltd. under which LEGO will have exclusive rights to manufacture, market, and distribute Star Wars construction toys.

With a new Star Wars movie scheduled for release in the United States in May 1999, LEGO planned to introduce its first assortment of LEGO building sets based on the original Star Wars trilogy in early 1999.

At the Learning Center, children can create their own robots and vehicles using programmable LEGO elements and LEGO’s specially developed software.

The LEGO Group Mission, Benefits, And Work Culture

We work with a broad definition of diversity, from gender, ethnicity, background and experience to other dimensions such as lifestyle and family responsibilities.

Inclusion starts with creating a safe space and helping everyone be seen, heard, valued and respected.

Our leadership model emphasises the importance of inclusion.

We work with a Diversity & Inclusion Council which represents employees across our diverse organisation and many locations.

We want our employees to play an active part in shaping the diversity and inclusion agenda.

That’s why we work to ensure that our creative content reflects society and the children who play with LEGO bricks.

In the survey, we set specific questions related to belonging, inclusion and psychological safety which we monitor and work with as part of our inclusion index.

Post Idea #25: Carbon monoxide detector

Related Articles – Summarized

Where Should I Place A Carbon Monoxide Detector?

Because carbon monoxide is slightly lighter than air and also because it may be found with warm, rising air, detectors should be placed on a wall about 5 feet above the floor.

Do not place the detector right next to or over a fireplace or flame-producing appliance.

If you are getting a single carbon monoxide detector, place it near the sleeping area and make certain the alarm is loud enough to wake you up.

Do CO alarms operate differently than smoke alarms?

To help protect your family from both hazards, it’s important to install both UL Listed CO alarms and smoke detectors.

Like smoke detectors, CO alarms need to be tested regularly and cleaned as indicated in the manufacturer’s use and care booklet.

If the unit operates off a battery, test the detector weekly and replace the battery at least once a year.

6 Best Carbon Monoxide Detectors For Aviation

To be proactive, and to be notified if carbon monoxide is present in the cabin of your aircraft, a carbon monoxide detector is recommended in all aircraft cabins.

There are many carbon monoxide detectors to choose from, and none are the wrong choice, but here are our picks for the best carbon monoxide detectors to keep in your cockpit.

The Sporty’s Pilot Shop Carbon Monoxide Detector is a low-cost, non-digital carbon monoxide detector.

Once installed, the carbon monoxide detector also acts as a clock, temperature gauge, cabin and density altitude sensor, and a carbon monoxide detector.

A carbon monoxide detector is a sensor that can detect the colorless, tasteless, and odorless gas known as carbon monoxide.

In some instances, carbon monoxide detectors can be recalibrated, but in most cases, the carbon monoxide detector will need to be replaced once it expires to ensure the accuracy of the sensor.

FAQ Do Airplanes Have Carbon Monoxide Detectors? Most aircraft owners do opt to have a carbon monoxide detector in the cockpit, but it is not required.

Carbon Monoxide Detector

Smoke alarms are powered by battery or by your home’s electrical system.

If the smoke alarm is powered by battery, it runs on either a disposable 9-volt battery or a non-replaceable 10-year sealed lithium battery.

There are many special features that can help protect you and your home, or make your safety products easier to maintain and operate.

Many of these features are not well known by their name, so to learn more about specific features of a model, select it and view its detail page.

‘Best’ models include many safety and convenience features.

‘Better’ models include a few safety and convenience features.

‘Good’ models include basic safety features.

Carbon Monoxide Detector

A carbon monoxide detector or CO detector is a device that detects the presence of the carbon monoxide gas to prevent carbon monoxide poisoning.

In the late 1990s Underwriters Laboratories changed the definition of a single station CO detector with a sound device to carbon monoxide alarm.

According to the 2005 edition of the carbon monoxide guidelines, NFPA 720, published by the National Fire Protection Association, sections and, all CO detectors “Shall be centrally located outside of each separate sleeping area in the immediate vicinity of the bedrooms,” and each detector “Shall be located on the wall, ceiling or other location as specified in the installation instructions that accompany the unit.”

Early designs used a chemical detector consisting of a white pad that faded to a brownish or blackish color in the presence of carbon monoxide.

New York State contractors have to install a carbon monoxide detector when replacing a fuel burning water heater or furnace if the home is without an alarm.

Alaska House Bill 351[when?] requires a carbon monoxide detector be installed in dwelling units that contain or are serviced by a carbon based fuel appliance or other device that produces by products of combustion.

In Maine all rental units must have carbon monoxide detectors and non rental homes are recommended but not required to have carbon monoxide detectors.

Post Idea #26: Garlock Sealing Technologies

Related Articles – Summarized

Leaders In Sealing Integrity

Garlock is proud to offer technical training from our engineering experts throughout the year.

From our multi-session Garlock Fluid Sealing Academy series to our Garlock Technical Insight sessions, we make sure you have the knowledge you need to select, install, and troubleshoot your Garlock products.

Garlock Sealing Technologies

ISC Companies and Adams-ISC can supply the Garlock Sealing products listed on this page and others found on garlock.com.

Garlock is acknowledged as the global leader in high-performance fluid sealing and pipeline protection products for specialty industries including chemical, refining, pulp and paper, water and wastewater treatment and drainage, power generation, primary metals, food and pharmaceuticals, infrastructure, mining, and more.

Garlock compression packing is tested to ensure effective sealing in valves, pumps, agitators, and other rotary equipment.

Garlock develops and manufactures both the technical yarn that is braided into the packing and the proprietary coatings, which are essential in sealing performance.

Garlock hydraulic components include heavy-duty packing and seals to meet the demanding requirements of reciprocating equipment.

Garlock KLOZURE mechanical seals for pumps, agitators, mixers, and other rotating shaft applications come in both lip and face seal designs and are available in four primary styles with a wide range of sizes.

Garlock KLOZURE oil seals are available in more than 50 different styles in sizes from in.

Garlock Sealing Technologies, LLC

Garlock has been named in hundreds of thousands of lawsuits alleging that the company’s sealing products exposed workers to asbestos and caused them to develop mesothelioma and other asbestos-related diseases.

Although Garlock began to phase out asbestos products in the 1970s, the use of its asbestos products in preceding decades set the stage for asbestos lawsuits.

A 2010 company press release revealed that Garlock Sealing Technologies had processed more than 900,000 asbestos claims and paid more than $1.4 billion in settlements and judgments.

Garlock sold two popular types of asbestos gaskets: sheet gasket material out of which gaskets were cut to size and pre-cut gaskets that were ordered to size.

Garlock asbestos gaskets combined asbestos fibers with fillers, elastomers, and curing agents.

Garlock asbestos packing was made from asbestos yarn coated with materials like Teflon or graphite.

Workers used a special tool that looked like a corkscrew to remove Garlock asbestos packing, and asbestos dust was created as the material was pulled out.

Garlock Sealing Technologies

Garlock Sealing Technologies, an Enpro Company that, produces sealing products.

The invention led to the creation of Garlock Sealing Technologies.

For a detailed history of Garlock from its founding in 1887 until the takeover by Colt Industries in 1976 see Garlock – The First Eighty-Eight Years 1887-1975 written by Robert M. Waples and son.

Garlock provides fluid sealing solutions for the following industries: petrochemical, chemical processing, and refining, pulp and paper, power generation, electronics, steel mills, food and pharmaceutical, mining and original equipment manufacturers.

Nippon Valqua – A strategic alliance, with Garlock enjoying exclusive sales rights for Nippon Valqua products in the Americas and Nippon Valqua having exclusive sales rights for Garlock products in Japan, South Korea and Taiwan.

Reynolds and his wife filed this personal injury action against 20 defendants, including Garlock Sealing Technologies LLC and Niagara Insulations, Inc., alleging that his disease was the result of workplace exposure to asbestos.

In a landmark January 2014 decision in the case In re Garlock Sealing Technologies, LLC, a U.S. bankruptcy judge set Garlock’s liability for all present and future claims at $125 million, a fraction of the $1.4 billion plaintiff lawyers sought.

Garlock Sealing Technologies, LLC V. Nak Sealing Technologies Corp., 148 Cal.App.4th 937

After Garlock settled the lawsuit with Rockwell, Garlock filed this action against its suppliers of the oil seals, NAK Sealing Technologies Corporation, formerly Mao Shun Oil Seal Industrial Company, Ltd., and Sunrise Trading Company, LLC. Mao Shun and Sunrise Trading each filed cross-complaints against each other.

Mao Shun appeals the trial court’s judgment awarding Garlock damages for Mao Shun’s breach of the implied warranty of merchantability and ordering Mao Shun to indemnify Sunrise Trading for its costs of defending the Garlock action.

Contrary to Mao Shun’s claim that Garlock specified Mao Shun’s standard brown viton “With full knowledge of the problems that Rockwell was experiencing,” the evidence, which Mao Shun does not fully or adequately summarize, shows the leakages reported to Garlock in the second quarter of 1998, for the very small number of brown viton seals that were in use at that time, were not chronic or widespread. There is no evidence Garlock or anyone else had knowledge that such leakages related to the iron oxide pigment used by Mao Shun in its standard brown viton.

Mao Shun attacks the trial court’s award to Garlock of consequential damages and contends Garlock obtained the standard remedy for breach of a warranty when prior to any litigation Mao Shun provided replacement seals at no charge.

Mao Shun complains Garlock had knowledge of leakage problems as early as 1997 and that it was not reasonably foreseeable Garlock would fail to disclose this information to Sunrise Trading or Mao Shun and would continue to sell brown viton oil seals to Rockwell when it knew they were failing.

Based solely on the abrasiveness of the brown viton oil seal Mao Shun manufactured which Garlock supplied to Rockwell, Garlock breached the implied warranty of merchantability it gave to Rockwell and no resort to any further or additional warranties would have been necessary for Garlock to have been liable to Rockwell in the federal lawsuit for the damages caused by its breach.

Based on these conclusions, we affirm the trial court’s judgment awarding Garlock damages for Mao Shun’s breach of the implied warranty of merchantability and ordering Mao Shun to indemnify Sunrise Trading for its costs of defending the Garlock action.

Garlock Sealing Technologies

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Post Idea #27: Chimeric antigen receptor

Related Articles – Summarized

Chimeric Antigen Receptor Therapy

Chimeric antigen receptor T cells were recently approved by the Food and Drug Administration and are poised to enter the practice of medicine for the treatment of leukemia and lymphoma.

Chimeric antigen receptor T cells for sustained remissions in leukemia.

Chimeric antigen receptor T cells in refractory B-cell lymphomas.

T cells expressing an anti-B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma.

Brudno JN, Kochenderfer JN. Toxicities of chimeric antigen receptor T cells: recognition and management.

Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.

Integrating proteomics and transcriptomics for systematic combinatorial chimeric antigen receptor therapy of AML. Cancer Cell.

Chimeric Antigen Receptor T-Cell Therapy

The T cells are sent to a laboratory or a drug manufacturing facility where they are genetically engineered, by introducing DNA into them, to produce chimeric antigen receptors on the surface of the cells.

The T cells are known as “Chimeric antigen receptor T cells.” CARs are proteins that allow the T cells to recognize an antigen on targeted tumor cells.

Deaths have been reported in CAR-T cell therapy trials.

An important factor in the safe and successful use of CAR T cells is choosing the proper tumor-associated antigen to target.

Damage to such noncancerous normal tissue by CAR T cells may pose life-threatening risks, especially when cells in essential tissues such as the heart, lung or liver express the target antigen.

CAR T-cell therapy targeting antigens found on the surface of B cells not only destroys cancerous B cells but also normal B cells.

Relapses may be due to the tumor cells losing the expression of the cluster of differentiation antigen, the limited persistence of CAR T cells, or inhibition of CAR T-cell activity.

Chimeric Antigen Receptor

Clustering of CARs induced by antigen binding on the surface of tumor cells initiates signal transduction that leads to T cell activation and killing of tumor cells.

58,59 Unlike TCRs, CARs engage molecular structures independent of antigen processing by the target cell and independent of MHC; recognition features that are desirable as an approach to overcome resistance mechanisms found in tumors and chronic infection.

Varying the affinity can increase the therapeutic index of CAR T cells, by increasing the discrimination of normal tissue expression from levels of surrogate antigen expressed on tumors.

Swapping CD4 transmembrane domain with CD28 in CD4 CARs designed to target HIV gp120 envelope protein demonstrated increased activation, cytolysis of infected cells, and enhanced cytokine production possibly through inducing homodimerization of chimeric molecules.

In addition to the CD3ζ signaling cassette, two costimulation cassettes are included [37-40]. T cells engineered with third-generation CARs have superior function, proliferative capacity, and survival in vivo compared to T cells engineered with second-generation CARs [37-40].Another consideration in CAR design is the relative affinity of the scFV. In general, Fab fragments have higher affinity for antigen than TCRs have for peptide MHC complexes.

CARs are introduced into normal T cells via gene transfer techniques, which redirect the cells towards a specific antigen in a manner that is independent of the major histocompatibility complexes.

Adoptive transfer of CAR nTregs with TNP-specific chimeric receptor expression in a transgenic mouse model of colitis was associated with antigen-specific, dose-dependent amelioration of the disease.

Chimeric Antigen Receptor T Cell

Chimeric antigen receptor T cells are T cells that have been genetically engineered to produce an artificial T cell receptor for use in immunotherapy.

The receptors are chimeric because they combine both antigen-binding and T cell activating functions into a single receptor.

The first chimeric receptors containing portions of an antibody and the T cell receptor was described in 1987 by Yoshihisa Kuwana et al.

A first generation CAR containing a CD4 extracellular domain and a CD3ζ intracellular domain was used in the first clinical trial of chimeric antigen receptor T cells by the biotechnology company Cell Genesys in the mid 1990s, allowing adoptively transferred T cells to target HIV infected cells, although it failed to show any clinical improvement.

These unique bispecific adaptors are constructed with a FITC molecule and a tumor-homing molecule to precisely bridge the universal CAR T cell with the cancer cells, which causes localized T cell activation.

The major control techniques trigger T cell death or limit T cell activation, and often regulate the T cells via a separate drug that can be introduced or withheld as needed.

Multifunctional alginate scaffolds for T cell engineering and release: Multifunctional alginate scaffolds for T cell engineering and release is a technique for in situ engineering, replication and release of genetically engineered T cells.

What Is Chimeric Antigen Receptor-T Cell Therapy?

Survival rates have improved as advances develop in treatment, such as chimeric antigen receptor-T cell therapy.

CAR-T cell therapy is a personalized treatment giving hope to patients diagnosed with various lymphomas.

For those who do not respond to two or more lines of such treatments, CAR-T cell therapy may be an option.

“Prior to the advent of CAR-T cell therapy, patients who had failed two lines of chemotherapy had a very poor survival of around six months,” Iqbal said.

Receiving CAR-T cell therapy can take a few weeks as a patient’s T cells, which normally help fight off infections, are collected and genetically engineered to target lymphoma.

The modified cells are infused back into the patient.

These cells can then attack and destroy the lymphoma.

Considerations For The Development Of Chimeric Antigen Receptor T Cell Products

Chimeric antigen receptor T cell products are human gene therapy products in which the T cell specificity is genetically modified to enable recognition of a desired target antigen for therapeutic purposes.

This guidance is intended to assist sponsors, including industry and academic sponsors, developing CAR T cell products.

In this guidance, we, FDA, provide CAR T cell specific recommendations regarding chemistry, manufacturing, and control, pharmacology and toxicology, and clinical study design.

Recommendations specific to autologous or allogeneic CAR T cell products are noted in this guidance.

This guidance also provides recommendations for analytical comparability studies for CAR T cell products.

While this guidance specifically focuses on CAR T cell products, much of the information and recommendations provided will also be applicable to other genetically modified lymphocyte products, such as CAR Natural Killer cells or T cell receptor modified T cells.

These related product types can be highly specialized, and in many cases, considerations beyond those recommended in this guidance would depend on the specific product and manufacturing process.

Chimeric Antigen Receptors That Trigger Phagocytosis

Chimeric antigen receptors are synthetic receptors that reprogram T cells to kill cancer.

The success of CAR-T cell therapies highlights the promise of programmed immunity and suggests that applying CAR strategies to other immune cell lineages may be beneficial.

Here, we engineered a family of Chimeric Antigen Receptors for Phagocytosis that direct macrophages to engulf specific targets, including cancer cells.

CAR-Ps consist of an extracellular antibody fragment, which can be modified to direct CAR-P activity towards specific antigens.

By screening a panel of engulfment receptor intracellular domains, we found that the cytosolic domains from Megf10 and FcRɣ robustly triggered engulfment independently of their native extracellular domain.

Addition of a tandem PI3K recruitment domain increased cancer cell engulfment.

Finally, we show that CAR-P expressing murine macrophages reduce cancer cell number in co-culture by over 40%. Keywords: Chimeric Antigen Receptor; Fc Receptor; cancer biology; cell biology; human; macrophages; mouse; phagocytosis; receptors; signal transduction.

Post Idea #28: Hodgkin’s lymphoma

Related Articles – Summarized

Hodgkin’S Lymphoma

Hodgkin’s lymphoma is a type of cancer that affects the lymphatic system, which is part of the body’s germ-fighting immune system.

Hodgkin’s lymphoma, which used to be called Hodgkin’s disease, is one of two general categories of lymphoma.

The extra cells crowd into the lymph nodes and cause swelling and other Hodgkin’s lymphoma signs and symptoms.

This much rarer type of Hodgkin’s lymphoma involves lymphoma cells that are sometimes called popcorn cells because of their appearance.

Nodular lymphocyte-predominant Hodgkin’s lymphoma is usually diagnosed at an early stage and may require less intensive treatments compared to the classical type of the disease.

Having a blood relative with Hodgkin’s lymphoma increases your risk of developing Hodgkin’s lymphoma.

People who have had illnesses caused by the Epstein-Barr virus, such as infectious mononucleosis, are more likely to develop Hodgkin’s lymphoma than are people who haven’t had Epstein-Barr infections.

What Is Hodgkin Lymphoma?

To understand what Hodgkin lymphoma is, it helps to know about the lymph system.

The lymph system is made up mainly of cells called lymphocytes, a type of white blood cell.

Lymph tissue is in many parts of your body, so Hodgkin lymphoma can start almost anywhere.

Although Hodgkin lymphoma can start almost anywhere, most often it starts in lymph nodes in the upper part of the body.

Hodgkin lymphoma most often spreads through the lymph vessels from lymph node to lymph node.

Enlarged lymph nodes in people with cHL usually have a small number of Reed-Sternberg cells with a lot of normal immune cells around them.

The cancer cells in NLPHL are large cells called popcorn cells, which are variants of Reed-Sternberg cells.

Find Out About This Cancer

Hodgkin Lymphoma Is a cancer that affects the lymphatic system, which is part of the body’s immune system.

Is named for Dr. Thomas Hodgkin who, in 1832, described several cases of people with symptoms of a cancer involving the lymph nodes.

What You Should Know Hodgkin lymphoma results from a change to the DNA of a lymphocyte, a type of white blood cell.

Hematologists and oncologists are specialists who treat people who have Hodgkin lymphoma or other types of blood cancer.

Be sure you know your Hodgkin lymphoma subtype because different subtypes have different treatments.

Hodgkin lymphoma starts when an abnormal change to the DNA of a white blood cell causes it to become a lymphoma cell that, if untreated, results in the uncontrolled growth of cancerous lymphocytes.

Hodgkin lymphoma is distinguished from other types of lymphoma by the presence of Reed-Sternberg cells.

MD Anderson Cancer Center

Between 8,000 and 9,000 people are diagnosed with Hodgkin lymphoma in the United States each year and the disease is most frequently diagnosed among people between the ages of 20-34, according to data from the National Cancer Institute.

Almost all Hodgkin lymphoma cases contain Reed-Sternberg cells, a specific type of large cancer cell that is not found in non-Hodgkin lymphomas.

Hodgkin lymphoma is divided into two major types according to how the lymph cells look under a microscope and whether Reed-Sternberg cells are present.

Nodular Sclerosing Hodgkin Lymphoma: The affected lymph nodes have mixed areas of normal cells, Reed-Sternberg cells and prominent scar tissue.

Mixed Cellularity Hodgkin Lymphoma: The affected lymph nodes contain many Reed-Sternberg cells in addition to several other cell types.

Lymphocyte-Rich Hodgkin Lymphoma: This recently created subtype in the past was sometimes confused with lymphocyte-predominant lymphoma.

Lymphocyte Depletion Hodgkin Lymphoma: Large numbers of Reed-Sternberg cells, but very few other cell types, are found in the lymph nodes.

Hodgkin’S Lymphoma: Treatment, Outlook

Hodgkin’s lymphoma makes up about 10 percent of lymphoma cases.

Hodgkin’s lymphoma is further divided into classic Hodgkin’s lymphoma and nodular lymphocytic predominant Hodgkin’s lymphoma.

The lymph nodes of people with classic Hodgkin’s lymphoma generally contain a small number of Reed-Sternberg cells surrounded by normal-looking immune cells.

If you don’t have any of the above symptoms, your stage is given the letter A. Treatment for Hodgkin’s lymphoma typically depends on the stage of the disease.

Brentuximab vedotin is a new drug that’s used to treat a specific type of Hodgkin’s lymphoma called CD30-positive Hodgkin’s lymphoma.

Advances in the treatment of Hodgkin’s lymphoma over the past few decades have greatly increased the survival rate.

If caught early, Hodgkin’s lymphoma tends to have a good outlook.

Causes, Symptoms & Treatments

Hodgkin lymphoma symptomsCauses of Hodgkin lymphoma.

Treatment for Hodgkin lymphoma will depend on how advanced the disease is as well as your age, symptoms and overall health.

In advanced Hodgkin lymphoma, chemotherapy is the principal treatment.

As well as slowing the spread of Hodgkin lymphoma, palliative treatment can relieve pain and help manage other symptoms.

Treatment TeamDepending on your treatment, your treatment team may consist of a number of different health professionals, such as:GP- looks after your general health and works with your specialists to coordinate treatment.

Cancer nurses- assist with treatment and provide information and support throughout your treatment.

There are no proven measures to prevent lymphoma people with an HIV infection or Epstein-Barr virus have an increased risk of contracting lymphoma.

Hodgkin Lymphoma

Hodgkin lymphoma is an uncommon cancer that develops in the lymphatic system, which is a network of vessels and glands spread throughout your body.

The most common symptom of Hodgkin lymphoma is a painless swelling in a lymph node, usually in the neck, armpit or groin.

Hodgkin lymphoma can develop at any age, but it mostly affects people between 20 and 40 years of age and those over 75.

Around 2,100 people are diagnosed with Hodgkin lymphoma in the UK each year.

The only way to confirm a diagnosis of Hodgkin lymphoma is by carrying out a biopsy.

Hodgkin lymphoma is a relatively aggressive cancer and can quickly spread through the body.

Overall, around 8 out of 10 people with Hodgkin lymphoma live at least 5 years and most of these will be cured.

Post Idea #29: Hellenic Statistical Authority

Related Articles – Summarized

Οικονομικός Ταχυδρόμος

The Industrial Turnover Index for the month of September 2021, compared to the corresponding index of September 2020, showed an increase of 39.6%, compared to a decrease of 10.3%, recorded during the corresponding comparison of the year 2020 with 2019, according to the provisional data announced by the Hellenic Statistical Authority.

The Industrial Turnover Index for the month of September 2021, compared to the corresponding index of August 2021, showed an increase of 25.3%. The average General Index, during the period of October 2020 to September 2021, compared to the corresponding index, during the period of October 2019 to September 2020, showed an increase of 14.5%, compared to a decrease of 10.8%, during its previous twelve months.

The changes in the indices of the double-digit sectors mainly contributed to this increase: coke production and oil refining products, manufacturing of electrical equipment, production of basic metals, manufacturing of metal products.

This increase was due to changes in the indicators of the double-digit sectors: mining, other mines and quarries.

Hellenic Statistical Authority

The Hellenic Statistical Authority, known by its acronym ELSTAT, is the national statistical service of Greece.

Law 2392/1996 provided for the arrangement of issues concerning the access of the General Secretariat of the National Statistical Service of Greece to administrative sources and files, as well as statistical confidentiality issues.

The Hellenic Statistical Authority collects data pertaining to the population, health and social security, employment and unemployment, education, etc.

He assumed the responsibilities of the President of the Hellenic Statistical Authority in February 2016, by virtue of a decision issued by the Minister of Finance.

It establishes and implements the annual statistical programme, produces and disseminates as the “National Statistical Institute”, in compliance to paragraph 1 of article 5 of Regulation No 223/2009, the official, national and European Statistics of the country, and conducts any kind of regular or ad hoc statistical surveys, censuses and studies.

It cooperates with the European Statistical Office – Eurostat and the other services of the European Commission, the National Statistical Institutes of the other Member States and the national authorities defined in the next paragraph, and with other international agencies and organisations on statistical issues and participates in the relevant statistical committees of the European Union and of other international organisations as the “National Statistical Institute”.

It cooperates with public and private agencies in Greece or abroad, such as educational institutions, research centers and non-profit organisations for the promotion of scientific research for statistical issues, the harmonization of methodology and the implementation of the statistical principles of the Hellenic and European Statistical Systems.

Post Idea #30: Crayola LLC

Related Articles – Summarized


Crayola, LLC claims the Crayola brand has 99% name recognition in U.S. consumer households, and says its products are marketed and sold in over 80 countries.

In 1949, Crayola introduced the “Crayola No. 48” containing 48 color crayons in a non-hangable floor box.

Crayola markers were introduced in 1978 to coincide with the 75th anniversary of Crayola crayons.

In August 1997, Crayola collaborated with Alliance Atlantis and the entertainment arm of Hallmark Cards to release three direct-to-video adaptations of famous children’s novels under the name Crayola Kids Adventures.

In 2000, Crayola held the “Crayola Color Census 2000” promotion in which Americans were asked to vote for their favorite Crayola crayon color.

Open to the public, the Crayola Experience is a roomy, crayon-centric warehouse including events, a cafe, a store, attractions, some familiarizing guests, and Crayola’s history with products.

Crayola LLC produces a broad range of products other than their famous crayons under the Crayola brand name.

Crayola LLC

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Happy National Crayon Day! Thank you so much for the crayon hand sanitizers! Our groups loved them! 🖍#nationalcrayonday #crayola 🖍I just love crayons because my Grade 4s do! Crayola crayons help bring out the imagination of kids in my classroom! #HappyNationalCrayonDayCelebrate #NationalCrayonDay-or any day of the year-with this fun crayon activity.

Whether you have a box of 8, 24, or 64, join as he scratches to reveal this colorful art technique! Watch here:Educators, you are missing out if you haven’t used dry erase markers! These are the BEST and my number 1 go to for dry erase markers! 😍❤️Today is National Crayon Day.

Don’t be GREEN with envy, there is still time to celebrate! Happy National Crayon Day from my kindergarten classroom Happy #NationalCrayonDay! Last week our #ATLairportART program installed six large-scale sculptures, entitled Ripple, by artist.

Happy #NationalCrayonDay! The first box of crayons was produced in 1903.

Crayola #CrayonDay2022Happy #NationalCrayonDay🌈 Fun fact: 3 billion crayons a year, about 12 million each day, is produced right here in the Lehigh Valley-proud home of the factory!Happy National Crayon Day! Reply with your favorite color name.

Did you know Mister Rodgers helped pour ‘s 100 billionth crayon? The crayon was poured in 1996 and was a limited-edition color Blue Ribbon.

Happy #NationalCrayonDay ! We are teaming up with to bring the Crayola Experience back to Maimonides park on July 10th!My colorful world! happy Principal Life! Happy National Crayon Day!🌸 Kicked off #NationalCrayonDay with a special conversation with the author of the Crayon Man! Thanks to Natascha Biebow for speaking with the students and teaching them about the creation of !Thank you to our friends from for generously donating items for our patients to enjoy in honor of #NationalCrayonDay.

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